Chongqing University Research Articles

Sorafenib plus partial splenic embolism for treatment of hepatocellular carcinoma Barcelona stage C combined with hypersplenism: a case series.

BackgroundSorafenib is mainly used to treat patients with hepatocellular carcinoma (HCC) Barcelona Clinic Liver Cancer (BCLC) stage C, many of whom also have severe cirrhosis. However, hypersplenism and digestive tract hemorrhage are common complications of cirrhosis, which increase the risk and difficulty of treatment.MethodsNineteen patients with HCC BCLC stage C with hypersplenism were treated with sorafenib plus partial splenic embolism at Chongqing University Cancer Hospital, Chongqing, China, between January 2015 and June 2018. We analyzed the therapeutic effect and clinical safety of this treatment in these patients.ResultHypersplenism was rectified in all patients. The incidence rates of hemorrhage and myelosuppression were 0%, and the mean survival time was 11.2 months.ConclusionSorafenib plus partial splenic embolism could relieve hypersplenism and prolong survival in patients with BCLC stage C HCC.

Circulating Tumor DNA Methylation Markers for Differential Diagnosis of Hepatocellular Carcinoma

Background: An effective blood-based method for hepatocellular carcinoma (HCC) early detection has not yet been developed. Aberrant DNA methylation may offer opportunities in revolutionizing cancer screening and diagnosis. We sought to identified a non-invasive DNA methylation-based diagnostic approach using cell-free DNA for HCC early detection in high risk population. Methods: Differentially methylated DNA methylation blocks were determined by comparing methylation profiles of biopsy-proven HCC, cirrhotic and healthy liver tissues using targeted bisulfite sequencing. A multi-layer HCC screening model was subsequently constructed based on tissue-derived differentially methylated makers using plasma samples from 120 HCC patients, 92 cirrhotic patients and 290 healthy individuals. This model was independently validated in a cohort consisting of 67 HCC patients, 115 cirrhotic patients and 242 healthy individuals. The clinical parameters of misclassified samples were also investigated. Findings: Based on methylation profiling of tissue samples, a total of 2,321 DNA methylation markers were derived, which were subsequently used to construct a cfDNA-based HCC screening model, achieving a sensitivity of 86% and specificity of 97% in the training cohort and a sensitivity of 82% and specificity of 96% in the independent validation cohort. The HCC screening model can effectively discriminate HCC patients from non-HCC patients, including patients with cirrhosis, HBV infection and healthy individuals, achieving an AUC of 0.956; whereas serum alpha-fetoprotein (AFP) achieved an AUC of 0.803. Interpretation: We have developed and validated an HCC screening model which can effectively distinguish early stage HCC patients from cirrhotic patients and symptomatic HBsAg-seropositive individuals. Funding: Key Research and Development Program of Hunan Province, Natural Science Foundation of Hunan Province, China. Declaration of Interest: None to declare. Ethical Approval: The study was approved by the ethic committee of The Second Xiangya Hospital of Central South University (KYLL2018072) and Chongqing University Cancer Hospital (2019167). All collection and usage of human sample and clinical data were in accordance with the principles of the Declaration of Helsinki. Written informed content was obtained from every participant for the use of their tissue or plasma samples.

Psychological Capital Mediates the Relationship Between Problematic Smartphone Use and Learning Burnout in Chinese Medical Undergraduates and Postgraduates: A Cross-Sectional Study.

Learning burnout is a pressing issue among Chinese medical undergraduates and Postgraduates and has drawn continuous attention worldwide. Studies have found that problematic smartphone use could affect learning burnout, but more research is needed in this direction. Furthermore, few studies focused on the mediating effect of psychological capital on the relationship between problematic smartphone use and learning burnout. The present study was a cross-sectional survey that recruited 1,800 participants from a medical university in Chongqing, China. A questionnaire based on the Mobile Phone Addiction Tendency Scale, Psychological Capital Questionnaire, Learning Burnout Scale, and demographic variables were administered to these students, and 1,475 provided valid responses (81.94%). 771 were undergraduates (52.3%) and 704 were postgraduates (47.7%). Hierarchical regression and the bootstrap method were used to examine the mediating effect of psychological capital. After controlling for demographic variables, problematic smartphone use positively predicted learning burnout in undergraduates (β = 0.328, p < 0.01) and in postgraduates (β = 0.342, p < 0.01). The partial mediating effect of psychological capital was 0.068 in undergraduates and 0.074 in postgraduates, accounting for 20.67 and 21.64%, respectively, of the total effect of problematic smartphone use on learning burnout. All the 95% confidence intervals (CI) did not contain 0. Problematic smartphone use can directly predict learning burnout and their relationship was mediated by psychological capital in Chinese medical undergraduates and postgraduates. Strategies to alleviating problematic smartphone use and enhance psychological capital in medical undergraduates and postgraduates may provide useful suggestions for future interventions on dealing with learning burnout in Chinese medical undergraduates and postgraduates.

Preface

This proceeding includes original and peer-reviewed research papers from 5th International Symposium on Resource Exploration and Environmental Science (REES 2021). Due to the current COVID-19 pandemic, REES 2021 was held ONLINE via Tencent Meeting/VooV Meeting on April 24-25, 2021. REES 2021 is organized by Wuhan University of Technology, co-organized by Wuhan University, Huazhong University of Science and Technology, Northeast Petroleum University, Research Center of Engineering and Science, sponsored by China Nonferrous Metals Group, Camel Battery Co., Ltd., Daye Nonferrous Metals, Chishun Chemical Co., Ltd.The REES conference is an annual conference, any delay will mean the interruption of academic exchanges. Therefore, the conference organizing committee requested that the conference be held as scheduled. The members of the conference organizing committee arranged the details of the conference at the Thai Jin Jiang International Hotel in Ordos.Due to the time difference, the number of overseas participants in this REES conference had decreased compared with previous conferences. The peak number of online participants in this conference was 330. With the collaboration of the members of the organizing committee, the software maintainers, and the conference participants, this 5th REES was successfully held, and the conference organizing committee gained valuable experience in holding online meeting. More importantly, the overall technical quality of the conference was reduced by the way of virtual conference. And many scholars of geology and geography had joined our conference enthusiastically. REES conference series had gained respect in the scientific community.The organizing committees are very grateful indeed to the presence of Prof. S. Jiang who from China University of Geosciences, Prof. Y. Xiong from Wuhan University, and Prof. J. Xu from Northeast Petroleum University. We also wish to thank the plenary and invited speakers: Prof. Liu from East China University of Technology, Dr. Xu from Chongqing University, Dr. Song from Beijing Institute of Astronautical Systems Engineering, Dr. Ma from Peking University, etc. Hopefully, the next REES conference could exchange new ideas and application experiences face to face.List of Committees are available in this Pdf.

Mobile Phone Addiction Mediates the Relationship Between Alexithymia and Learning Burnout in Chinese Medical Students: A Structural Equation Model Analysis.

BackgroundLearning burnout is a passive mental state among students. It is a common phenomenon that can cause many bad outcomes in Chinese medical students, such as mental disorders and suicide, and its causes are complex.PurposeTo analyze the relationship between alexithymia and learning burnout, as well as the mediating effect of mobile phone addiction, and provide clues for future interventions to deal with learning burnout among Chinese medical students.MethodsIn this cross-sectional study, convenience cluster sampling was used to produce a sample of 1200 medical universities in Chongqing, China. The Toronto Alexithymia Scale (TAS-20), Mobile Phone Addiction Tendency Scale (MPATS), and Learning Burnout Questionnaire (LBQ) were used to examine participants. Hierarchical regression was used to analyze the effect of alexithymia and mobile phone addiction on learning burnout. A structural equation model (SEM) with maximum likelihood was used to evaluate the mediating effect of mobile phone addiction on the relationship between alexithymia and learning burnout. The bootstrap method was used to confirm the significance of this mediating effect.ResultsThe final sample size was 1062, with a valid response rate of 88.5%. The prevalence of learning burnout among Chinese medical students was 39.6%. Results of hierarchical regression revealed that alexithymia (ΔR2=0.198, P<0.01) and mobile phone addiction (ΔR2=0.021, P<0.01) were independent factors of learning burnout; the SEM revealed that the mediating effect of mobile phone addiction between alexithymia and learning burnout accounted for 25.16% of the total effect of alexithymia on learning burnout; the bootstrap method revealed that the bounds of the CI did not contain 0, confirming the significance of this mediating effect.ConclusionOf the medical students, 39.6% had learning burnout. Alexithymia can positively predict learning burnout, and this relationship is partially mediated by mobile phone addiction.

Editorial: Solid-state electrolytes and solid-state batteries for next-generation energy storage

Functional Materials LettersVol. 14, No. 03, 2102001 (2021) No AccessEditorial: Solid-state electrolytes and solid-state batteries for next-generation energy storageHiroki Nagai and Shufeng SongHiroki NagaiSchool of Advanced Engineering, Kogakuin University, Tokyo 1920015, Japan and Shufeng SongCollege of Aerospace Engineering, Chongqing University, Chongqing 400044, P. R. Chinahttps://doi.org/10.1142/S179360472102001XCited by:1 Next This article is part of the issue: Topical Issue: Solid-State Electrolytes and Solid-State Batteries for Next-Generation Energy StorageGuest Editors: Hiroki Nagai and Shufeng Song AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail

Green manufacturing literature during three decades: A scientometric approach

The research aimed to map the global green manufacturing academic literature indexed by Scopus by using a scientometric approach and analysis was done by using the analysis search results service from Scopus and the VOSviewer application. The research data consisted of 1,386 academic literature published from 1993 to 2019 were obtained from the Scopus database. The results show that the most productive countries, research institutions, and individual researchers in green manufacturing literature were China; Chongqing University; and Liu, F. The most intensive subject areas and sources of publications in green manufacturing literature are engineering and the Applied Mechanics and Materials. There are six collaborative researchers’ group patterns. The research proposes a convergence axis classification consisting of green manufacturing literature to characterize the body of knowledge generated from three decades of publications: machining, environment, sustainable development, energy, manufacture, computer science, and tools.

Self-assembly 2D plasmonic nanorice film for surface-enhanced Raman spectroscopy* *Project supported by the National Natural Science Foundation of China (Grant No. 11974067), Natural Science Foundation Project of CQ CSTC (Grant Nos. cstc2019jcyj-msxmX0145, cstc2019jcyj-bshX0042, and cstc2019jcyj-msxmX0828), and Sharing Fund of Chongqing University & Large-scale Equipment.

As an ultrasensitive sensing technology, the application of surface enhanced Raman spectroscopy (SERS) is one interesting topic of nano-optics, which has huge application prospectives in plenty of research fields. In recent years, the bottleneck in SERS application could be the fabrication of SERS substrate with excellent enhancement. In this work, a two-dimensional (2D) Ag nanorice film is fabricated by self-assembly method as a SERS substrate. The collected SERS spectra of various molecules on this 2D plasmonic film demonstrate quantitative detection could be performed on this SERS substrate. The experiment data also demonstrate this 2D plasmonic film consisted of anisotropic nanostructures has no obvious SERS polarization dependence. The simulated electric field distribution points out the SERS enhancement comes from the surface plasmon coupling between nanorices. And the SERS signals is dominated by molecules adsorbed at different regions of nanorice surface at various wavelengths, which could be a good near IR SERS substrate for bioanalysis. Our work not only enlarges the surface plasmon properties of metal nanostructure, but also exhibits the good applicationprospect in SERS related fields.

Preface

The 2021 International Online Conference on Mechanical Engineering, Intelligent Manufacturing and Automation Technology (MEMAT 2021-Online) was planned to be held on January 15-17, 2021in Guilin, China. Taking into account the COVID-19 pandemic, the MEMAT 2021-Online conferencewas held virtually as agencies around the world are now issuing restrictions on travel, gatherings, and meetings in an effort to limit and slow the spread of this pandemic. The health and safety of our participants and members of our research community is of top priority to the Organizing Committee. Therefore, the MEMAT 2021-Online conference was held online through Zoom software.MEMAT 2021-Online is to bring together innovative academics and industrial experts in the field of Mechanical Engineering, Intelligent Manufacturing and Automation Technology to a common forum. The primary goal of the conference is to promote research and developmental activities in engineering materials, manufacturing technology and another goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be held every year to make it an ideal platform for people to share views and experiences in Mechanical Engineering, Intelligent Manufacturing, Automation Technologyand related areas.More than 130 participants attended the online conference, they were from China, France,Singapore and more. We were greatly honor to have invited Prof.Ziad Moumni, Shanghai JiaotongUniversity, France to as our Conference Chair.During the conference, the conference model was divided into four sessions, including oralpresentations, academician reports, keynote speeches, and online Q&A discussion. In the first part, some scholars, whose submissions were selected as the excellent papers, were given about 5-10 minutes to perform their oral presentations one by one. Then in the second and third part, keynote speakers were each allocated 30-45 minutes to hold their speeches. In the academician reports part, we were greatly honor to have invited Huanbing Liu, Foreign academician of Russian Academy of Engineering, from South China University of Technology to presented his insightful report. Another academician reporter, C. L. Philip Chen, being a Program Evaluator of the Accreditation Board of Engineering and Technology Education (ABET) in the U.S, from South China University of Technology also presented a wonderful report. In the third part, we invited six professors as our keynote speakers. They were Prof.Shiji Song, from Tsinghua University; Prof.David BASSIR, from University of Bourgogne Franche-Comté (UTBM) & Researcher at ENS-CMLA; Prof.Qixin Cao, from Shanghai Jiao Tong University; Prof.Liang Yan, from Beihang University; Prof.Deping Yu, from Sichuan University; Prof.Huajun Cao, from Chongqing University. Their insightful speeches had triggered heated discussion in the fourth session of the conference. Every participant praised this conference for disseminating useful and insightful knowledge.The proceedings are a compilation of the accepted papers and represent an interesting outcome of the conference. Topics include but are not limited to the following areas: Mechanical Engineering, Intelligent Manufacturing, Automation and Other related topics. All the papers have been through rigorous review and process to meet the requirements of International publication standard.This year, we have all worked and lived with the daily threat of COVID19, the need for social distancing and relative isolation has impacted upon the familiar and fundamental nature of conferences. Regardless, such interactions are the lifeblood of our respective communities, and so we made the decision to proceed with the Workshop, bring participants together from around the world through a digital platform. We would like to acknowledge all of those who supported MEMAT 2021-Online. The help and contribution of each individual and institution was instrumental in the success of the conference. In particular, we would like to thank the organizing committee for its valuable inputs in shaping the conference program and reviewing the submitted papers.Committee of MEMAT 2021-OnlineList of Committee members are available in this pdf.

Peer review declaration

All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the Editors. Reviews were conducted by expert referees to the professional and scientific standards expected of a proceedings journal published by IOP Publishing.• Type of peer review: Double-blind • Conference submission management system: AI Scholar Submission System • Number of submissions received: 356 • Number of submissions sent for review: 331 • Number of submissions accepted: 230 • Acceptance Rate (Number of Submissions Accepted/Number of Submissions Received X 100): 64.6% • Average number of reviews per paper: 2 • Total number of reviewers involved: 150 • Any additional info on review process: • Step 1. Each of the selected papers should be reviewed by two or three experts who are professional in the related area. A report of the reviewing result will come out by each expert. • Step 2. After collecting the reviewing reports from the experts, one of the editors will review the reports and decide whether the reports are approved. • Step 3. After that, the editors inform the authors of the reviewing results along with the three reviewing reports. • Step 4. Authors are required to revise their paper according to the requirements, then hand in the revised version to the editors. The editors send the revised version to reviewers and will decide whether the paper is approved to be published according to the reviewers’ final reports. And at last the editors inform the decision with every details of the publication requirements if the paper is accepted. • Contact person for queries: • Yongkang Xing • Chongqing University • ykxing@cqu.edu.cn

Wire fracture in postoperative Nuss procedure: a problem that cannot be ignored.

BackgroundSurgical stainless wire has been widely used to stabilize pectus bar and ribs in Nuss procedure for pectus excavatum correction. However, wire fracture and its secondary complications are problems easily to be ignored but very important. The purpose of this article was to describe a series of cases with wire breakage, hoping to arouse the attention of worldwide thoracic surgeons to this potential threat, and to share our modifications on the fixation patterns and materials in Nuss procedure.MethodsFrom September 2011 to January 2020, 44 patients underwent Nuss procedure at Chongqing University Three Gorges Hospital. In the initial 25 patients (Group A), each bar was secured by stainless wires, and the latter 19 patients (Group B) received stainless wires and polyblend polyethylene sutures (PDS) in the bar fixation. Patient demographics, Haller index (HI), wire fracture rate, characteristics of the broken wires, and operation time were recorded.ResultsThe mean operation age was 8.1±4.3 years in group A and 10.4±2.9 years in group B. There was no statistical difference in HIs between the two groups (P>0.05). The wire fracture occurred in 88.0% of the patients in Group A, while the wires in Group B were all intact. There was no bar displacement or other serious complication requiring surgical intervention in the two groups. The mean operation time of bar removal when encountering wire fracture was 104.6±42.8 minutes, which was significantly higher than that in Group B (P≤0.001).ConclusionsThe wire fracture in the bar fixation could pose potential hazards to patients deserving special attention from thoracic surgeons. Cancel the wire fixation in the non-stabilizer side while simultaneously using wires and PDS in the pectus bar fixation may achieve the pectus bar stability while overcoming the problem of wire fracture.

Preface

It is our great pleasure to welcome you to the 2021 5th International Workshop on Advanced Algorithms and Control Engineering (IWAACE 2021) on February 26-28, 2021, which is planned to held in Zhuhai, China. However, due to the spread of COVID-19, many countries have strict restrictions to travel aboard. Meanwhile, the safety of the participants is always the priority. We made a hard decision to hold the conference online.IWAACE 2021 is to bring together innovative academics and industrial experts in the field of Advanced Algorithms and Control Engineering to a common forum. The primary goal of the conference is to promote research and developmental activities in Advanced Algorithms and Control Engineering and another goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be held every year to make it an ideal platform for people to share views and experiences in Algorithms and Control Engineering and related areas.This scientific event brings together more than 120 national and international researchers. During the conference, the conference model was divided into three sessions, including oral presentations, keynote speeches, and online Q&A discussion. In the first part, some scholars, whose submissions were selected as the excellent papers, were given about 5-10 minutes to perform their oral presentations one by one. Then in the second part, keynote speakers were each allocated 30-45 minutes to hold their speeches.In the second part, we invited four professors as our keynote speakers. Prof. Xinguo Yu, the dean and Professor of CCNU Wollongong Joint Institute and Professor of National Engineering Research Center for E-Learning Adjunct professor of University of Wollongong, Australia, performed a speech: Automatic Problem Solving for Basic Education. And then we had Assoc. Prof. Xiang Zhou from School of Data Science, City University of Hong Kong, China. He presented a talk: Machine Learning and Control Theory. He introduced the recent ongoing joint work with Alain Bensoussan and Phillip Yam about a new numerical method for computing the gradient of the value function. Dr. Deepak Kumar Jain, School of Automation, Chongqing University of Posts and Telecomunications, Chongqing, China as our third keynote speakers. Our finale keynote speakers, Dr. Badrul Hisham bin Ahmad, Universiti Teknikal Malaysia Melaka / Faculty of Electronics and Computer Engineering, Malaysia was invited to present his talk Design and Development of VHF FRONT-END for lightning interferometer system. Their insightful speeches had triggered heated discussion in the third session of the conference. Every participant praised this conference for disseminating useful and insightful knowledge.The proceedings are a compilation of the accepted papers and represent an interesting outcome of the conference. Topics include but are not limited to the following areas: Communication Technology and Applications, Computer Engineering, Network Engineering and Application Technology, Intelligent System, Electronics and Electrical Engineering and more related topics. All the papers have been through rigorous review and process to meet the requirements of International publication standard.We would like to acknowledge all of those who supported IWAACE 2021. The help and contribution of each individual and institution was instrumental in the success of the conference. In particular, we would like to thank the organizing committee for its valuable inputs in shaping the conference program and reviewing the submitted papers.The Committee of IWAACE 2021List of Committee member is available in this pdf.

Preface

This is certainly a great way to end the year after organizing another remarkable conference in the year 2020. Unlike previous years, due to on-going pandemic, the 4th series of NCWE was held through the long distance mode (on-line). The decision to hold the virtual conference was made after a mutual consent was received from all the collaborators. As the future of the vaccine development and the progress was undecided the organizing committee was not ready to postpone the already planned event for the benefit of everyone involved. However, no compromise was made with the strict standard operating procedure (SOP) outlined by the government and also paying heed to the closure of international borders by many countries including Malaysia. These proactive measures were taken to minimize the physical contact among participants and to curb the spreading of COVID-19. Yet, NCWE did not fail to draw a lot of participants across the region including India, Pakistan, China, Bangladesh, Vietnam, Thailand and Japan. We from the organizing team were overwhelmed and felt privileged when we were given the opportunity to organise the 4th National Conference on Wind and Earthquake Engineering (NCWE) 2020 which was held virtually from the Chancellery Hall of Universiti Malaysia Pahang (UMP) on the 16th and 17th October 2020.This virtual conference was organized with the support from Universiti Sains Malaysia, Chongqing University (China), Beijing Jiaotong University (China) and the Universitas Syiah Kuala (Indonesia). The conference tentatives were divided into three parallel sections for each day. Each presenters were given options to either perform a 10 minutes virtual presentation using a live ZOOM application or otherwise a pre-recorded slide was shown followed by a Q & A slot which lasted 5 to 10 minutes. Also an hour was dedicated to each keynote presenters at the beginning of each parallel session. As expected, the papers submitted were more than 100 and fellow reviewers have put their heart and soul in making sure only the best quality research and technical papers were selected for virtual presentation and publication. In line with the theme of the conference “Get Ahead”, NCWE 2020 have seen much success in providing a common platform to discuss issues, challenges, opportunities and technologies relating with the wind and earthquakes engineering. This proved that no pandemic can stop the academic proliferation; in fact, we could not agree more when NCWE 2020 had reached a larger audience and a higher number of paper submissions were received indeed.This volume of conference proceedings not only has a good selection of refereed papers but there are more to it. You will find a compilation of 5 keynote lectures given by; Professor Dr. Yukio Tamura, a prominent professor at Chongqing University, China, Professor Dr. Shuyang Cao from Tongji University, China, Professor Ir. Dr. Taksiah A. Majid from Universiti Sains Malaysia, Dr. Ichwana Ramli, from Universitas Syiah Kuala, Indonesia and finally Associate Professor Dr. Guoqing Jing from the Beijing Jiaotong University. The most awaited presentation from Professor Tamura with his topic on ”Characteristics of pedestrian- level winds around tall and super-tall buildings: Effects of configurations, height, width, size, aspect ratio, and flow conditions’ gained full credits from the participants when many questions and comments were discussed before the next turn. The same acknowledgement was made for the topic “Physical and numerical modelling of Boundary-layer-wind-induced load on structures” presented by Professor Shuyang Cao. Many of the keynote topics discussed here were highly relevant with our daily life issues and triggered healthy discussions and sharing of knowledge among participants. Organizing committee also has made some effort to record all the keynote presentations and posted the videos on YouTube for the benefit of everyone.The National Conference on Wind and Earthquake Engineering (NCWE) of 2020 also served as a new platform to researchers and scholars from different disciplines that have interest in sustainable construction, agricultural technology and environmental sciences to share and discuss their research findings. There were some 100 participants including students, engineers, researchers and academicians who took part virtually and had many fruitful discussions and exchanges which again contributed to the success of this conference. Finally on behalf of the organizing committee of NCWE 2020, I would like to thank all the presenters and participants for their great support. Last but not least, let us join our hands together in supporting out front liners battling COVID-19 pandemic.Chairman, NCWE 2020 DR. MOHAMAD IDRIS ALI

Preface

It was a great pleasure to welcome all the participants from different countries to the 2020 3rd International Symposium on Power Electronics and Control Engineering (ISPECE 2020) was be held on November 26-28, 2020 in Chongqing, China. ISPECE 2020 is to bring together innovative academics and industrial experts in the field of Power Electronics and Control Engineering to a common forum. The primary goal of the conference is to promote research and developmental activities in Power Electronics and Control Engineering and another goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be held every year to make it an ideal platform for people to share views and experiences in Power Electronics and Control Engineering and related areas.The conference model was divided into two sessions, including oral presentations and keynote speeches. In the first part, some scholars, whose submissions were selected as the excellent papers, were given 15 minutes to perform their oral presentations one by one. Then in the second part, keynote speakers were each allocated 30-45 minutes to hold their speeches. In this conference, we were greatly honor to invited Prof. Yuanchang Zhong from Chongqing University, China to serve as our Conference Chairman. There were over 180 experts and scholars representing different famous universities and institutes around the globe to attend the conference.During the conference, we invited seven industry elites to present their insightful speeches. The first keynote speaker, Prof. Goh Hui Hwang, from Department of Electrical Engineering, Guangxi University, China. His technical interests and expertise include electrical engineering, power systems, renewable and sustainable energy, embedded power generation, wavelet analysis, load shedding, and data mining. Prof. Junhua Xiong, North China University of Water Resources and Electric Power, China, shared a speech: Control method for improving power quality of high-permeability photovoltaics connected to low-voltage distribution network. Her method has been applied to the project of Xuji Group Co., Ltd. in Australia, and the operation results show that the method has good effect on power quality improvement. The third keynote speakers, Assoc. Prof. GHAMGEEN IZAT RASHED, from Wuhan University-School of Electrical Engineering and Automation, China. His special research of interest in AI and its application to the power system, FACTS devices specially TCSC and its control. Prof. Long Li, School of Electronic Engineering, IEEE Senior Member. His main research directions include electromagnetic metamaterials and metasurfaces, new antennas and microwave circuits, electromagnetic compatibility, wireless power transfer and energy harvesting, and so on. Prof. Ke Jin, from Nanjing University of Aeronautics and Astronautic. His main research includes power electronic topology and control, power electronic system integration, wireless power transmission, etc. Prof. YinQuan Yu, from East China Jiaotong University. His research activities are design and analysis Smart Permanent Magnet Synchronous Motor (PMSM), Machine Health Monitoring and Fault Diagnosis, Mechatronics and Robotics, Shock Absorption and Noise Reduction of High-speed and Highprecision Equipment, Intelligent Manufacturing and Precision Machining. The finale keynote speaker, Prof. Long Xiao, from Electromagnetic Compatibility Laboratory at China Ship Development and Design Center. He was mainly engaged in the research of far-field high-power microwave wireless energy transmission technology.We are glad to share with you that we received lots of submissions from the conference and we selected a bunch of high-quality papers and compiled them into the proceedings after rigorously reviewed them. These papers feature following topics but are not limited to: Power Electronics, Control Engineering, Mechanical Engineering and other related topics. All the papers have been through rigorous review and process to meet the requirements of International publication standard.We are really grateful to the International/National advisory committee, keynote speakers, session chairs, organizing committee members, student volunteers and administrative assistance of the management section of University, including accounts section, digital media and publication house. Also, we are thankful to all the authors for contributing a large number of papers in the conference, because of which the conference became a story of success. It was the quality of their presentations and their passion to communicate with the other participants that really make this conference series a great success.The Organizing Committee of ISPECE 2020List of Committee member, Conference Chair, Organizing Committees Chairman, Organizing Committees are available in this pdf.

Preface

At present, COVID-19 is still having an enormous impact in global areas. International or long-distance travels are still risky. In consideration of the safety of all speakers and participants, 2nd International Conference on International Conference on Artificial Intelligence and Cloud Computing(ICAICC2020), organized by Yaseen academy, Wuhan, China, had been held online via Tencent Meeting at Dec, 19, 2020.There are 3 speakers from Zhengzhou University of Industry Technology, Chongqing University of Posts and Telecommunications and Guizhou University of Traditional Chinese Medicine respectively and 10 participants in total. Every speaker was given about 25-30 minutes including the Q&A time, the detailed information for the speeches can be found via this link: http://www.yaseen.org.cn/NewsDetail.aspx?ID=94This Conference looks for significant contributions to all major fields of Artificial Intelligence and Cloud Computing in theoretical and practical aspects. The aim of the conference is to provide a platform to the researchers and practitioners from both academia as well as industry to meet and share cutting-edge development in the field.All accepted papers included into this collection have undergone careful peer-review by at least two reviewers before being selected for publication. They went through the peer-reviewed process by conference committee members and reviewers to ensure their compliance to meet the required standard for qualified scientific publications.We would like to thank the editors, all staff, the Committee members, all the reviewers and everyone who had worked for and lending a hand in reviewing papers and making valuable suggestions for the improvement of the conference. Special thanks go to IOP Publishing for their sincere help and high efficiency in publishing and indexing for all articles.Jianxin ZhangYaseen AcademyICAICC 2020 Organizing Committee

Floquet bands and photon-induced topological edge states of graphene nanoribbons* *Project supported by the starting foundation of Chongqing University (Grant No. 0233001104429), the National Natural Science Foundation of China (Grant No. 11847301), and the Fundamental Research Funds for the Central Universities, China (Grant No. 2020CQJQY-Z003).

Floquet theorem is widely used in the light-driven systems. But many 2D-materials models under the radiation are investigated with the high-frequency approximation, which may not be suitable for the practical experiment. In this work, we employ the non-perturbative Floquet method to strictly investigate the photo-induced topological phase transitions and edge states properties of graphene nanoribbons under the light irradiation of different frequencies (including both low and high frequencies). By analyzing the Floquet energy bands of ribbon and bulk graphene, we find the cause of the phase transitions and its relation with edge states. Besides, we also find the size effect of the graphene nanoribbon on the band gap and edge states in the presence of the light.

Higher Education Curriculum Evaluation Method Based on Deep Learning Model.

Higher education plays an important role in the improvement of people's quality and the development of our country. Therefore, it is necessary to evaluate the higher education curriculum. This paper analyzes and constructs the deep network learning system and self-encoder and evaluates the Chongqing higher education curriculum based on the deep learning network selected by 50 universities in Chongqing. It is found that the numbers of test objects, indicators, and hidden layers have an impact on the evaluation results. At the same time, a classroom teaching model is designed to improve the quality of higher education and solve the problem of insufficient curriculum quality of higher education.

Preface

It was a great pleasure to welcome all the participants from different countries to the 2020 International Conference on Smart Grid and Energy Engineering in Guilin, China during November 13-15, 2020. This three-day conference was organized by AEIC Academic Exchange Information Centre and co-organized by GUANGZHOU Computer Society. SGEE 2020 is to bring together innovative academics and industrial experts in the field of Smart Grid and Energy Engineering to a common forum. The primary goal of the conference is to promote research and developmental activities in Smart Grid and Energy Engineering and another goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be held every year to make it an ideal platform for people to share views and experiences in Smart Grid and Energy Engineering and related areas.The conference model was divided into two sessions, including oral presentations and keynote speeches. In the first part, some scholars, whose submissions were selected as the excellent papers, were given 15 minutes to perform their oral presentations one by one. Then in the second part, keynote speakers were each allocated 30-45 minutes to hold their speeches.In this conference, we are greatly honored to have invited Prof. Om P. Malik from University of Calgary, Canada to serve as our Conference Chairmen. During the conference, we were pleased to invite six distinguished experts to present their insightful speeches. The first keynote speaker, Prof. Z.Y. Dong, The University of New South Wales, Australia, held a speech on Promoting Renewable Energy with Virtual Power Plants. In this talk, the energy market rules which provides opportunities for VPP development were presented, together with methodologies on smart energy management for VPP applications. Prof. Juan Yu from Chongqing University, China, talked about Data-driven Methods for Operational Reliability Assessment of Power Systems Integrated with High-penetration Renewables. Her speech focusing on the computational efficiency of the operational reliability assessment in power systems that contain high penetration renewables, this presentation lays a theoretical foundation to support practical applications of an online high-accuracy operational reliability assessment. Prof. Alberto Borghetti, University of Bologna, Italy, shared a speech on his specialty related to Scheduling problems in local energy communities. This presentation is aimed to describe some models that could be useful for the operation of energy communities and distribution networks where trading between neighbors becomes significant. A/Prof. Farhad Shahnia, Murdoch University, Australia, made an insightful speech on Recent and Future Research on Microgrid Clusters. This talk briefly introduced the progress of research in this field around the world and Australia, and also discussed some of the technical challenges associated with interconnection of neighbouring microgrids as a key step to improve their survivability in the course of unexpected imbalances between the demand and the available generation from intermittent renewable resources. Prof. Xinyu Chen, Huazhong University of Science and Technology, China, delivered a speech: Towards Higher Penetration of Renewable Challenge and Opportunities. This talk focused on deepen the understanding of how the environmental regulations and low carbon polices influence the operation, planning and markets for power systems in different counties. As the last keynote speaker, Prof. Shouxiang Wang from Tianjin University, China. His research area: microgrid, smart distribution system, uncertainty analysis of power system.We are glad to share with you that we received lots of submissions from the conference and we selected a bunch of high-quality papers and compiled them into the proceedings after rigorously reviewed them. These papers feature following topics but are not limited to: Smart Grid Information Engineering, Electric Drive and Applications, Renewable Energy, Energy Efficiency and other related topics. All the papers have been through rigorous review and process to meet the requirements of International publication standard.We are really grateful to the International/ National advisory committee, keynote speakers, session chairs, organising committee members, student volunteers and administrative assistance of the management section of University, including accounts section, digital media and publication house. Also, we are thankful to all the authors for contributing a large number of papers in the conference, because of which the conference became a story of success. It was the quality of their presentations and their passion to communicate with the other participants that really make this conference series a great success.The Organizing Committee of SGEE 2020List of Committee member are available in this pdf.

Peer review declaration

All papers published in this volume of IOP Conference Series: Earth and Environmental Science have been peer reviewed through processes administered by the Editors. Reviews were conducted by expert referees to the professional and scientific standards expected of a proceedings journal published by IOP Publishing.• Type of peer review: Double-blind • Conference submission management system: AI Scholar Submission System • Number of submissions received: 292 • Number of submissions sent for review: 275 • Number of submissions accepted: 190 • Acceptance Rate (Number of Submissions Accepted / Number of Submissions Received X 100): 65.1% • Average number of reviews per paper: 2 • Total number of reviewers involved: 130 • Any additional info on review process: • Step 1. Each of the selected papers should be reviewed by two or three experts who are professional in the related area. A report of the reviewing result will come out by each expert. • Step 2. After collecting the reviewing reports from the experts, one of the editorswill review the reports and decide whether the reports are approved. • Step 3. After that, the editors inform the authors of the reviewing results along with the three reviewing reports. • Step 4. Authors are required to revise their paper according to the requirements, then hand in the revised version to the editors. The editors send the revised version to reviewers and will decide whether the paper is approved to be published according to the reviewers' final reports. And at last the editors inform the decision with every details of the publication requirements if the paper is accepted. • Contact person for queries: Yongkang Xing, Chongqing University, ykxing@cqu.edu.cn

The Short Isoform TET1s Retards Oscillatory Shear Flow-Induced Atherosclerosis Through CX40-Dependent Endothelial Cell Barrier Enhancement

Background: TET1 has been implicated in regulating inflammation and cardiovascular disease, but a newly discovered short isoform of TET1 (termed TET1s) exhibits higher expression in adult tissues than full-length TET1. However, the precise role of TET1 in cardiovascular disease remains undefined. Methods: To assess the function of TET1s in atherosclerosis development, ApoE-/-TET1-/- mice and ApoE-/-TET1cs/cs mice were generated. Atherosclerotic plaques were evaluated by Oil red staining and endothelial permeability was accessed by Evans blue staining. Oscillatory shear stress (OSS) model generated by carotid artery ligation. Overexpressing TET1s in primary HUVECs was used to access the function of TET1s in vitro. Findings: We found that TET1s deletion in TET1-/- mice resulted in more serious atherosclerotic lesions in the whole aorta than TET1cs/cs in the ApoE-/- background mice. Atherosclerotic lesions were dramatically localized in the aortic arch, abdominal aorta and ligated LCA, where they were exposed to OSS. Furthermore, the OSS-induced depression of TET1s in vitro and in vivo impaired the vascular intimal barrier. TET1s upregulation enhanced vascular endothelial barrier function by increasing CX40 expression through increases histone acetylation levels in the CX40 promoter via its interaction with Sin3a. Interpretation: These data demonstrate TET1s expression to protect OSS-induced atherosclerosis through enhancing vascular endothelial barrier by increasing CX40 expression in ECs Funding: The work is supported by the Natural Science Foundation of China (31971242, 12032007), Chongqing Science and Technology Bureau (cstc2019jcyj-zdxmX0028) and Fundamental Research Funds for Central Universities (2019CDYGZD008, 2019CDYGYB016, 2021CDJCGJ007). Declaration of Interest: All authors declare no conflict of interest Ethical Approval: All animal procedures and patients sample study were reviewed and approved by the Animal Care and Ethic Committee of Chongqing University.