Bacterial infections are the most eminent public health challenge of the 21st century. The primary step leading to infection is bacterial adhesion to the surface of host cells or medical devices, which is mediated by a multitude of molecular interact... Read More
Biophysical Research Articles
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1082 Articles
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The biophysics of bacterial infections: Adhesion events in the light of force spectroscopy.
- Cell surface (Amsterdam, Netherlands)
- VOL. 7
on Dec 1, 2021
- Force Spectroscopy
- Events
- Interface
- Interactions
- AFM
- Surface Of Host Cells
- More +
Design and Analysis of Mechanical Microswimmers
- Journal of Bioscience & Biomedical Engineering
on Nov 4, 2021
- Elliptical Head
- Spherical Head
- Medical World
- Low Reynolds Number
- ANSYS FLUENT
- Biomedical Applications
- More +
The fascinating field in present civilization scenario at the edge of science is micro-swimmers, which is a combination of bio physics with self-propulsion mechanisms involving swimming strategies at low Reynolds number. These micro swimming robots o... Read More
Therapeutic lithium alters polar head-group region of lipid bilayer and prevents lipid peroxidation in forebrain cortex of sleep-deprived rats.
- Biochimica et biophysica acta. Molecular and cell biology of lipids
- VOL. 1866
on Sep 1, 2021
- Hydrophobic Lipid Core
- Cortex
- Peroxidative Damage Of Membrane Lipids
- Sleep Deprivation
- Laurdan
- Plasma
- More +
Lithium is regarded as a unique therapeutic agent for the management of bipolar disorder (BD). In efforts to explain the favourable effects of lithium in BD, a wide range of mechanisms was suggested. Among those, the effect of clinically relevant con... Read More
The long chain base unsaturation has a stronger impact on 1-deoxy(methyl)-sphingolipids biophysical properties than the structure of its C1 functional group.
- Biochimica et Biophysica Acta
- VOL. 1863
on Aug 1, 2021
- Biophysical
- Hereditary Sensory And Autonomic Neuropathy
- Sphingoid Base
- Double
- 1-deoxy-sphingolipids
- Autonomic Neuropathy Type
- More +
Abstract 1-deoxy-sphingolipids, also known as atypical sphingolipids, are directly implicated in the development and progression of hereditary sensory and autonomic neuropathy type 1 and diabetes type 2. The mechanisms underlying their patho-physiolo... Read More
Hyperthermia Selectively Destabilizes Oncogenic Fusion Proteins.
- Cancer Discovery
- VOL. 2
on Jul 1, 2021
- APL
- Refractory APL
- SIAH2
- Resistance
- APL Cases
- Hyperthermia
- More +
The PML/RARα fusion protein is the oncogenic driver in acute promyelocytic leukemia (APL). Although most APL cases are cured by PML/RARα-targeting therapy, relapse and resistance can occur due to drug-resistant mutations. Here we report that thermal ... Read More
Commentary: Revamping graduate biophysics education
- Physics Today
- VOL. 2021
on Jun 23, 2021
- Biophysics
FVIIIa-mimetic bispecific antibody (Mim8) ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
- Blood
on Jun 2, 2021
- FX
- HA
- Emicizumab
- Plasma
- Bispecific Antibody
- Hemophilia
- More +
Hemophilia A (HA) is a bleeding disorder resulting from deficient Factor VIII (FVIII), which normally functions as a cofactor to activated Factor IX (FIXa) that facilitates activation of Factor X (FX). To mimic this property in a bispecific antibody ... Read More
Understanding connectivity of pearl oyster populations within Tuamotu atoll semi-closed lagoons: Cumulative insight from genetics and biophysical modelling approaches.
- Marine Pollution Bulletin
- VOL. 167
on Jun 1, 2021
- Biophysical
- Connectivity
- Biophysical Modelling
- Black Lipped Pearl Oyster Pinctada
- Pearl Oyster
- Biophysical Modelling Approaches
- More +
Abstract Connectivity affects species demography, (meta)population dynamics, evolution, phylogeny and biogeography. Various methodological approaches are applied to measure connectivity. Biophysical modelling can explore systematically the influence ... Read More
Investigation of shielding properties of impregnated activated carbon for gamma-rays.
- Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
- VOL. 172
on Jun 1, 2021
- Effective Atomic Number
- Gamma
- Use Of Radioactive Sources
- TVL
- Gamma Shielding Properties
- Shielding Materials
- More +
Carbon related structures are extraordinarily attractive materials for researchers and especially for organic chemistry, besides being the most important basic materials of daily life. The richness of various optical and electronic behaviors has made... Read More
Normalized chlorophyll fluorescence imaging: A method to determine irradiance and photosynthetically active radiation in phytoplankton cultures
- Algal Research-Biomass Biofuels and Bioproducts
- VOL. 56
on Jun 1, 2021
- Photosynthetically Active
- Fluorescence Imaging Method
- Chlorophyll
- Photobioreactors
- Fluorescence Imaging
- Phytoplankton Cultures
- More +
Abstract In order to expand microalgae's use as a mainstream biotechnological resource, the efficiency of light capturing in culture vessels must be optimised. As a response to the complex nature of microalgal culture vessel modelling, it is importan... Read More
Role of pulmonary surfactant protein Sp-C dimerization on membrane fragmentation: An emergent mechanism involved in lung defense and homeostasis.
- Biochimica et Biophysica Acta
- VOL. 1863
on Jun 1, 2021
- SP-C
- Pulmonary Surfactant System
- Bimolecular Fluorescence Complementation
- Lung Defense
- Eve Nt
- Protein C
- More +
Abstract Surfactant protein C (SP-C) is a protein present in the pulmonary surfactant system that is involved in the biophysical properties of this lipoprotein complex, but it also has a role in lung defense and homeostasis. In this article, we propo... Read More
Auxiliary subunits of the AMPA: The Shisa family of proteins.
- Current Opinion in Pharmacology
- VOL. 58
on Jun 1, 2021
- Biophysical
- AMPA
- Auxiliary Proteins
- Interaction
- Proteins
- Auxiliary Subunits
- More +
Abstract AMPA receptors mediate fast synaptic transmission in the CNS and can assemble with several types of auxiliary proteins in a spatio-temporal manner, from newly synthesized AMPA receptor tetramers to mature AMPA receptors in the cell membrane.... Read More
Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry.
- Antioxidants (Basel, Switzerland)
- VOL. 10
on Jun 1, 2021
- ETD
- Oxidation Of Methionine Residues
- Top-Down Mass Spectrometry
- PTM
- Native Mass Spectrometry
- Oxidation Of Methionine
- More +
The formation of multiple proteoforms by post-translational modifications (PTMs) enables a single protein to acquire distinct functional roles in its biological context. Oxidation of methionine residues (Met) is a common PTM, involved in physiologica... Read More
All the questions about biophysics
- Journal Club for Condensed Matter Physics
on May 31, 2021
- Biophysics
Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling
- Innovation-the European Journal of Social Science Research
- VOL. 2
on May 28, 2021
- MD2
- TLR4
- Nicotinic
- Cotinine
- Cellular Thermal Shift Assay
- LPS-induced Production Of Nitric Oxide
- More +
Nicotine is the principal alkaloid of tobacco often manufactured into cigarettes and belongs to a highly addictive class of drugs. Nicotine attenuates the neuroinflammation induced by microglial activation. However, the molecular target(s) underlying... Read More
Fe(II) metallohelices stabilize DNA G-quadruplexes and down-regulate expression of G-quadruplex regulated oncogenes.
- Chemistry: A European Journal
on May 28, 2021
- Promoter
- Human Embryonic Kidney
- Development Of New Drugs
- Promoter Regions Of c-MYC
- Elongation
- DNA G4s
- More +
DNA G-quadruplexes (G4s) were identified within the promoter regions of many proto-oncogenes. Thus, G4s represent attractive targets for cancer therapy and the design and development of new drugs as G4 binders is a very active field of medicinal chem... Read More
Convection-Enhanced Delivery and Principles of Extracellular Transport in the Brain: Extracellular Transport in the Brain.
- World Neurosurgery
on May 24, 2021
- Biophysical
- Convection-enhanced Delivery
- Stereotactic
- Applications In Radiosurgery
- Areas
- Extracellular Space
- More +
Abstract Stereotactic neurosurgery involves a targeted intervention based on congruence of image-guidance to a reference fiducial system. This discipline now has widespread applications in radiosurgery, tumor therapy, drug delivery, functional lesion... Read More
Biomaterials for intestinal organoid technology and personalized disease modelling.
- Acta Biomaterialia
on May 20, 2021
- Biophysical
- Organoid
- Intestinal Organoid
- Organoid Systems
- Intestinal Cells
- Hydrogels
- More +
Abstract Recent advances in intestinal organoid technologies have paved the way for in vitro recapitulation of the homeostatic renewal of adult tissues, tissue or organ morphogenesis during development, and pathogenesis of many disorders. In vitro mo... Read More
3 QUESTIONS ON... How to Prove Alternative, Cost-Effective Treatments Are Just As Good: With Ian Tannock, MD, PHD, Emeritus Professor of Medicine and Medical Biophysics at Princess Margaret Cancer Centre
- Oncology Times UK
- VOL. 43
on May 20, 2021
- Biophysics
- Centre
- Princess Margaret Cancer Centre
- Medical Biophysics
- Cost-effective Treatments
- Medicine
- More +
The decreasing a negative impact of climate change on Indonesian food security
- Agrivita : Journal of Agricultural Science
- VOL. 43
on May 19, 2021
- Negative Impact Of Climate Change
- High Yielding Varieties
- Maintain Soil Organic Matter
- Victim Of Climate Change
- Indonesia's Food Security
- SOM
- More +
The negative Impact of climate change and food security are crucial issues for Indonesia with a large population. Agricultural sector as a contributor about 5-7 percent to CO 2 emissions, is a victim of climate change as this sector is very sensitive... Read More