New experiments in highly turbulent, steady, subcritical and uniform water open-channel flows have been carried out to measure the mean turbulent kinetic energy (TKE) budget of sediment-laden boundary layer flows with two sizes (dp = 3 mm and 1 mm) of Plexiglas particles $({\rm relative\ density}\ = 1.192)$ . The experiments covered energetic sediment transport conditions (Shields number of $0.35 < \theta < 1.2$ ) ranging from non-capacity to full-capacity flows in bedload-to-suspension-dominated transport modes (suspension number of $0.5 < {w_s}/{u_\ast } < 1.3$ where ${w_s}$ is the settling velocity and $u_*$ is the friction velocity) and for weakly to highly inertial, finite size turbulence-particle conditions (Stokes number of 0.1 < St < 3.5 and dp/η > 10 where $\eta$ is the Kolmogorov length scale). It was shown that the effects of sediments on the TKE budget are very pronounced in all large particle experiments for which a bedload layer of several grain diameter thickness is developed above the channel bed. When compared with the corresponding reference clear-water flows, the TKE shear-production rate for the 3 mm particle flows is strongly reduced in the wall region corresponding to the bedload layer. This turbulence damping is seen to increase with sediment load until full capacity for flows with constant Shields value, as well as with Shields number value. Inside this damped TKE shear-production zone, a distinct peak of maximal turbulence production appears to coincide with the upper edge of the bedload layer delimited by a sharp gradient in mean sediment concentration. This vertically upshifted peak of TKE production is accompanied by an enhanced net downward oriented TKE flux when compared with the reference clear-water flows. The downward diffused TKE is found to act in the bedload layer as a local energy source in reasonable balance with the sediment transport term. The mechanism behind this downward TKE transport was further analysed on the basis of coherent flow structure dynamics controlled by ejection- and sweep-type events. The agreement between the height of downward directed mean TKE flux and the height below which sweep-type events dominate the Reynolds shear-stress contribution over ejections, revealed the leading role played by sweeps in mean TKE transport. This agreement holds for all reference clear-water flows supporting the well-known wall-roughness-induced dominance of the sweep contribution in turbulent, rough clear-water boundary layer flows. Furthermore, for all 3 mm particle flows, the two referred to transition levels were significantly and similarly upshifted to the upper edge of the bedload layer. Only for these sediment-laden flows, the bedload layer thickness is seen to exceed the wall-roughness sublayer of the reference clear-water flows. This supports a strong analogy between wall-roughness effects in clear-water flows and bedload layer effects in sediment-laden flows, on the mean TKE budget induced by a similarly modified coherent flow structure dynamics. The bedload layer-controlled wall roughness is finally confirmed by the good prediction of the wall-roughness parameter ks of the logarithmic velocity distribution. An empirical formulation fitting the presented measurements is presented, valid over the range of Shields number values covered herein.