Average Percentage Research Articles

Genetic Diversity of Ramie (Boehmeria Nivea L. Gaudich.) Originating from Wonosobo and Malang Based on Simple Sequence Repeat (SSR) Molecular Markers

Ramie has been widely used as a fiber crop for over 4000 years. The fibers are durable, white in color, and smooth in texture. Information on genetic diversity is important for selecting good breeding materials to produce superior offspring. This study aimed at determining the genetic diversity of Boehmeria nivea (L.) Gaudich. from Wonosobo and Malang using SSR as molecular markers. Nineteen accessions of ramie were analyzed for genetic diversity using 9 SSRs located adjacent to the gene associated with fiber yield traits. This study included the DNA extraction, amplification, and visualization of amplification. Data analysis included the allele number, frequency, PIC value, heterozygosity, Shannon information index, and AMOVA analysis. The results showed 229 alleles, with an average polymorphic percentage of 68.67%, the average allele frequency ranging from 0.07 to 0.11, an average PIC value of 0.84, and Jaccard's similarity score of 0-0.18. The He and Ho values in both populations were 0.719 and 0.278, respectively. AMOVA analysis revealed that 88% of the observed molecular variance was due to genetic differences within the population, whereas 12% of genetic variation was partitioned between populations. The present study showed high genetic diversity between Wonosobo and Malang ramie. This finding might support further programs for the fiber and biomaterial industry.

Development of ICARE-Based Physics Teaching Materials to Improve Students' Critical Thinking Ability

Research on the development of ICARE-based teaching materials aims to: 1) analyze the results of the content validity of ICARE-based physics teaching materials which meet valid criteria, 2) analyze practitioners' assessments of ICARE-based physics teaching materials, 3) analyze the effectiveness of ICARE-based teaching materials. The test subjects of this research were 28 students of class XI Science at Sma Muhammadiyah 1 Unismuh. Research method with 4D models. The instruments used in this research were validation sheets, practitioner assessment questionnaires, and test instruments for students' critical thinking abilities. Practicality criteria are seen from practitioners' assessments of teaching materials, and effectiveness criteria are seen from the average percentage of students' critical thinking ability improvement scores. Based on the results of the analysis, the following conclusions were obtained: (1) ICARE-based teaching materials which were developed based on expert assessment using Aiken's V index analysis were declared valid and suitable for use with slight revisions; (2) ICARE-based physics teaching materials in terms of teacher responses were in the category Very good; (3) the effectiveness of ICARE-based physics teaching materials analyzed using N-gain obtained an average value of 0.50, which is included in the medium category, meaning there is an increase in students' critical thinking abilities so it can be said that the ICARE-based physics teaching materials developed are effective and can improve abilities. students' critical thinking.

The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus.

People with HIV-1 (PWH) on antiretroviral therapy (ART) can maintain undetectable virus levels, but a small pool of infected cells persists. This pool is largely comprised of defective proviruses that may produce HIV-1 proteins but are incapable of making infectious virus, with only a fraction (~10%) of these cells harboring intact viral genomes, some of which produce infectious virus following ex vivo stimulation (i.e. inducible intact proviruses). A majority of the inducible proviruses that persist on ART are formed near the time of therapy initiation. Here we compared proviral DNA (assessed here as 3' half genomes amplified from total cellular DNA) and inducible replication competent viruses in the pool of infected cells that persists during ART to determine if the original infection of these cells occurred at comparable times prior to therapy initiation. Overall, the average percent of proviruses that formed late (i.e. around the time of ART initiation, 60%) did not differ from the average percent of replication competent inducible viruses that formed late (69%), and this was also true for proviral DNA that was hypermutated (57%). Further, there was no evidence that entry into the long-lived infected cell pool was impeded by the ability to use the CXCR4 coreceptor, nor was the formation of long-lived infected cells enhanced during primary infection, when viral loads are exceptionally high. We observed that infection of cells that transitioned to be long-lived was enhanced among people with a lower nadir CD4+ T cell count. Together these data suggest that the timing of infection of cells that become long-lived is impacted more by biological processes associated with immunodeficiency before ART than the replication competency and/or cellular tropism of the infecting virus or the intactness of the provirus. Further research is needed to determine the mechanistic link between immunodeficiency and the timing of infected cells transitioning to the long-lived pool, particularly whether this is due to differences in infected cell clearance, turnover rates and/or homeostatic proliferation before and after ART.

Safety, efficacy, and clinical utility of the 5.1-mm debridement catheter for treatment of walled-off pancreatic necrosis (with video)

Background and AimsDirect endoscopic necrosectomy (DEN) is a recommended strategy for treatment of walled-off-necrosis (WON). DEN uses a variety of devices including the EndoRotor (Interscope, Inc.) debridement catheter. Recently, a 5.1 mm EndoRotor with increased chamber size and rate of tissue removal was introduced. The aim of this study was to assess the efficacy and safety of this device. MethodsA multi-center cohort study was conducted at eight institutions including patients who underwent DEN with the 5.1 mm EndoRotor. The primary outcome was the number of DEN sessions needed for WON resolution. Secondary outcomes included the average percent reduction in solid WON debris and decrease in WON area per session, total time spent performing EndoRotor therapy for WON resolution, and adverse events. Results64 procedures in 41 patients were included. For patients in which the 5.1 mm EndoRotor catheter was the sole therapeutic modality, an average of 1.6 DEN sessions resulted in WON resolution with an average cumulative time of 85.5 minutes. Of the 21 procedures with data regarding percent of solid debris, the average reduction was 85% +/- 23% per session. Of the 19 procedures with data regarding WON area, the mean area significantly decreased from 97.6 +/- 72.0 cm2 to 27.1 +/- 35.5 cm2 (p<0.001) per session. Adverse events included two intra-procedural LAMS dislodgements managed endoscopically and three perforations none of which were related to EndoRotor. Bleeding was reported in seven cases, none required embolic or surgical therapy and two required blood transfusions. ConclusionsThis is the first multi-center retrospective study to investigate the efficacy and safety of the 5.1 mm EndoRotor catheter for WON. Results from this study showed an average of 1.6 DEN sessions were needed to achieve WON resolution with an 85% single session reduction in solid debris and a 70% single session decrease in WON area with minimal adverse events.

The Disproportionate Rise in Pancreatic Cancer in Younger Women Is Due to a Rise in Adenocarcinoma and Not Neuroendocrine Tumors: A Nationwide Time-Trend Analysis Using 2001-2018 United States Cancer Statistics Databases.

In previous studies, a significant increase in the incidence of pancreatic cancer among younger women compared to men in the United States was noted. However, the specific histopathologic characteristics were not delineated. This population-based study aimed to assess whether this disproportionate rise in pancreatic cancer in younger women was contributed by pancreatic ductal adenocarcinoma (PDAC) or pancreatic neuroendocrine tumors (PanNET). The United States Cancer Statistics (USCS) database was used to identify patients with pancreatic cancer between 2001 and 2018. The results showed that, in younger adults, the incidence of PDAC has increased in women [average annual percentage change (AAPC) = 0.62%], while it has remained stable in men (AAPC = -0.09%). The PDAC incidence rate among women increased at a greater rate compared to men with a statistically significant difference in AAPC (p < 0.001), with neither identical nor parallel trends. In contrast, cases of PanNET did not demonstrate a statistically significant sex-specific AAPC difference. In conclusion, this study demonstrated that the dramatic increase in the incidence rate of PDAC explains the disproportionate rise in pancreatic cancer incidence in younger women. This prompts further prospective studies to investigate the underlying reasons for these sex-specific disparities in PDAC.

Determination of ITS1 haplotypes of Fritillariae Cirrhosae Bulbus by amplicon sequencing

BackgroundFritillariae Cirrhosae Bulbus is an antitussive and expectorant Chinese medicinal material derived from the dried bulbs of six Fritillaria species. In the 2015 edition of the Chinese Pharmacopoeia, the polymerase chain reaction-restriction fragment length polymorphism (PCR–RFLP) is the officially listed method for their authenfication. Specifically, the ~ 300-bp ITS1 amplicon of only Fritillariae Cirrhosae Bulbus but not other Fritillaria species can be cleaved into two smaller fragments with restriction enzyme SmaI. Considering repeated reported cases of incomplete digestion of ITS1 amplicon, this study aims to investigate the possibility of heterogeneous ITS1 sequences contained in the Fritillariae Cirrhosae Bulbus.MethodsIn this study, ITS1 amplicons of Fritillaria Cirrhosae Bulbus and four other Fritillaria species were sequenced on Illumina platform. We utilised high-throughout amplicon sequencing to determine ITS1 haplotypes and their frequencies in Fritillaria genomes.ResultsOur results showed that all six botanical sources of Fritillariae Cirrhosae Bulbus indeed possess ITS1 haplotypes with no SmaI restriction site, and the average percentages of ITS1 reads containing SmaI restriction site ranged from 63.60% to 91.81%.ConclusionOur findings suggest that the incomplete digestion in PCR–RFLP analysis of Fritillariae Cirrhosae Bulbus is caused by the presence of ITS1 haplotypes without SmaI restriction site due to intragenomic heterogeneity.

Quality Assessment and Evaluation of Amino Acid Profile of Black Wheat Supplemented Noodles

Background: Functional foods are a topic of ongoing industrial use and research. Currently, coloured grain is being prioritized more in research since it is a source of neutraceutical chemicals. Black colored wheat is known for its anthocyanin content. Black wheat therefore has the potential to offer extra health advantages over those that standard wheat cultivars typically offer. Noodles are most popular products widely consumed throughout the world and represents second in global consumption to bread. The present study was undertaken to evaluate effect of processing on loss of amino acids content in black wheat supplemented noodles and control white noodles. Methods: In the present study, High performance liquid chromatography was used for the quantification of amino acids in Black and Netravati white colored wheat flour and prepared black wheat supplemented noodles and control white noodles samples prepared by extrusion. Result: Black wheat flour and Black wheat supplemented noodles samples had higher total amino acid content, Essential amino acid content and per cent essential amino acid score in comparison Netravati white flour and control noodles samples prepared from whole Netravati white wheat flour, while content of lysine was more in Netravati white wheat flour and control noodles samples. The noodles samples prepared exhibited average percent reduction in amino acid content in black and Netravati white wheat were 1.06 and 2.63%, respectively. Black wheat flour and black wheat supplemented noodles were rich in anthocyanins also rich in amino acids in comparison to Netravati white wheat flour. Minimum losses in amino acid content were observed in Black wheat supplemented noodles, while maximum losses were observed in Netravati white wheat control noodles samples.

Web-Based Window Shopping: A Learning Model in High School's Mathematics Curriculum

The post-pandemic adaptation demands technological innovations in sustainable learning to support mathematics curriculums. This research aims to develop the Web-based Window Shopping (WBWS) in high school mathematics curriculum with ADDIE procedure. The data were collected through interviews, questionnaires, and tests. The stages of research comprised analysis, design, development, implementation, and evaluation. The experts' validation test results showed that the aspects of materials and medium achieved an average score of 82,75%. Meanwhile, the trial test results showed that the developed WBWS is worth implementing, with the average percentage of effectiveness reaching 83,33%. The results suggest that the creation of WBWS as a web-based learning model for mathematics curriculum is not only feasible but also meets the educational needs of high school students. Teachers and students can use this web-based learning model as an alternative for implementing the independent curriculum on mathematics learning.

Global and regional trends in the incidence and prevalence of uterine fibroids and attributable risk factors at the national level from 2010 to 2019: A worldwide database study.

Uterine fibroids (UFs), the most common tumors in women worldwide, may reduce quality of life and daily activities and even lead to adverse fertility and general health events in patients, causing significant societal health and financial burdens. The objective was to evaluate the global burden through epidemiological trends and examine the potential risk factors for UFs at the national level. Data on the incidence, prevalence, disability-adjusted life years (DALYs), age-standardized incidence rates (ASIRs), age-standardized prevalence rates (ASPRs), and age-standardized DALY rates for UFs were collected, and the associations with the Human Development Index (HDI) and fertility were evaluated. The age trends in the average annual percent change (AAPC) of the incidence and prevalence rates of UFs were evaluated by joinpoint regression analysis. The associations between lifestyle, metabolic, and socioeconomic factors and the ASIRs of UFs were examined using multivariable linear regression analysis. The worldwide incidence and prevalence of UFs have been increasing in the past decade, with AAPCs of 0.27% in the incidence rate and 0.078% in the prevalence rate. During 2010-2019, significant increasing trends in UF ASIR were observed in 52 of 88 countries. The age-specific incidence and prevalence of UFs in most age groups showed increasing trends except for 45-54-year-old women which showed no significant trend. Ecological analysis demonstrated no relationship between the incidence of UFs and the HDI but an inverse association with fertility. The incidence of UFs was positively correlated with alcohol intake, hypertension, overweight, and obesity and negatively correlated with smoking. With the increasing incidence and prevalence worldwide, effective targeted prevention and control of relevant risk factors at the national level should be encouraged to reduce the disease burden of UFs.

EVALUASI KOMPETENSI PENGAJAR MATRIKULASI UNIVERSITAS TRIBUANA KALABAHI TAHUN 2023

This evaluation research aims to evaluate the competence of matriculation teachers at Tribuana Kalabahi University which is based on student assessments to assess the competence of matriculation teachers in carrying out the learning process in the classroom which includes pedagogical competence, professional competence, personality competence and social competence. This evaluation activity is a routine activity carried out by LPM with the aim of ensuring that learning activities carried out by matriculation teachers have been carried out in accordance with the plans, objectives and standards or targets that have been set. This study uses a type of evaluation research with a quantitative approach using a survey method. The population in this study is 502 new students who took part in matriculation activities spread across 11 study programs at Tribuana Kalabahi University with data collection techniques using an online questionnaire. The data analysis technique uses descriptive statistics with percentage calculation techniques. The evaluation results show that in general the competency of matriculation lecturers can be concluded that the overall perception of respondents towards the 28 matriculation lecturers received a positive response with an average percentage score of 82.29% or in the High category. Pedagogical competence 81.14%, professional competence 82.55%, personality competence 83.80% and social competence 83.65%.

An exploratory study of history-based test case prioritization techniques on different datasets

In regression testing, Test case prioritization (TCP) is a technique to arrange all the available test cases. TCP techniques can improve fault detection performance which is measured by the average percentage of fault detection (APFD). History-based TCP is one of the TCP techniques that consider the history of past data to prioritize test cases. The issue of equal priority allocation to test cases is a common problem for most TCP techniques. However, this problem has not been explored in history-based TCP techniques. To solve this problem in regression testing, most of the researchers resort to random sorting of test cases. This study aims to investigate equal priority in history-based TCP techniques. The first objective is to implement different history-based TCP techniques. The second objective is to explore the problem of equal priority in history-based TCP techniques. The third objective is to explore random sorting as a solution to the problem of equal priority in history-based TCP techniques. Datasets of historical records of test cases from conventional and modern sources were collected. History-based TCP techniques were applied to different datasets. The History-based TCP techniques were checked for the problem of equal priority. Then random sorting was used as a solution to the problem of equal priority. Finally, the results were elaborated in terms of APFD and execution time. The results indicate that history-based techniques also suffer from the problem of equal priority like other types of TCP techniques. Secondly, random sorting does not produce optimal results while trying to solve the problem of equal priority in history-based TCP. Furthermore, random sorting deteriorates the results of history-based TCP techniques when employed to solve the problem of equal priority. One should resort to random sorting if no other solution exists. The decision to choose the best solution requires a cost-benefit analysis keeping in view the context and solution under consideration.

Pengembangan E-Book Interaktif Berbasis Kearifan Lokal untuk Pembelajaran Keterampilan Membaca Teks Berita SMPN 34 Padang

The background to this research is that technological developments are increasingly rapid in human life in various fields, one of which is education. This type of research uses Research and Development (R&amp;D). The development model used in this research is a 4-D model consisting of four stages, namely: 1) define, 2) design, 3) develop, and 4) disseminate. This research used a questionnaire instrument data collection technique which was distributed to class VIII students of SMP Negeri 34 Padang. Based on the results of the student needs questionnaire analysis, the results showed that 83% of students needed digital learning media. There are 3 aspects in the research questionnaire, namely student needs in the learning process aspect which obtained a percentage of 84%, student needs in the learning media aspect 84%, and student needs in the teaching material content aspect 80%. The average percentage result for all aspects is 83%, so it falls into the "very feasible" category. From the results of the analysis of the student needs questionnaire, it was concluded that researchers needed to develop learning media in the form of interactive e-books based on local wisdom.

Serum prolactin levels were positively related to metabolic indexes and disorders in male obese patients.

The role of prolactin (PRL) in glucolipid metabolism was inconsistent, and there were few studies on the metabolic role of PRL in obese patients. The study aims to explore association between PRL level and metabolic disorders in male obese patients. A retrospective study was conducted. Eighty-nine male patients with obesity were included, and their clinical data were recorded. A total of 89 male obese patients were included in this study. Their average age was 24.5 ± 9.0 years and BMI was 42.8 ± 9.1 kg/m2. The average waist circumference and body fat percentage was 129.6 ± 19.6 cm and 42.9 ± 8.0%, respectively. The median prolactin levels were 10.0 ng/ml (range: 3.93-30.1 ng/ml). 79.0% (49/62) of these patients presented with NAFLD and 77.3% (68/88) of them was dyslipidemia. Further, serum prolactin level was positively correlated with BMI (r = 0.225, P = 0.034), body fat percentage (r = 0.326, P = 0.017), ALT (r = 0.273, P = 0.011) and AST (r = 0.245, P = 0.029). Compared with low PRL group (<10 ng/ml), the incidence of morbid obesity and NAFLD was higher in high PRL group (morbid obesity: 71.1% vs 45.5%, P = 0.018 and NAFLD: 91.2% vs 64.3%, P = 0.013). In addition, the risk of NAFLD and morbid obesity in high PRL group (>10 ng/ml) was higher than low PRL group (OR:5.187, 95%CI 1.194-22.544, P = 0.028 and OR: 4.375, 95% CI 1.595-11.994, P = 0.004). The increased risk of NAFLD and morbid obesity in the high PRL group still existed after adjusting for age and Testosterone. Serum prolactin levels were positively associated with deterioration of metabolic indexes in male obese patients, as well as NAFLD and morbid obesity.

Thermal performance analysis of a novel Conical-Cylindrical-Conical cavity receiver for a Scheffler concentrated solar system

The thermal efficiency of a receiver is a critical component of the point focusing concentrated solar system, significantly impacting the overall system efficiency. A thermal performance analysis of the developed novel Conical-Cylindrical-Conical cavity receiver is carried out for the enhancement of its efficiency. The analysis involves varying aspect ratios (0.8, 1, and 1.2) of the receiver utilizing Computational Fluid Dynamics with ANSYS (Fluent 2023R1) and the discrete ordinates modeling technique. The simulation results reveal a peak thermal efficiency of 80.9 % for the receiver at mass flow rate of 0.035 kg/s. The experimental validation is performed using a 16 m2 concentrator solar Scheffler dish under real outdoor conditions in a hilly terrain of India. The average percentage error between the experimental results and the Computational Fluid Dynamics model simulation, is found to be 0.52 %.The results of study highlights the significant impact of design and aspect ratio on the thermal efficiency of the cavity receiver. This study is the first investigation into the aspect ratio of the novel Conical-Cylindrical-Conical cavity receiver for point focusing concentrated solar system, providing valuable insights for further research and industrial applications worldwide.

Development of Reciprocal Teaching-Based Interactive Multimedia to Enhance Students' Learning Outcomes of Database Fundamentals

Database subjects are one of the basic compulsory subjects for the Computer Engineering and Informatics program. For Software Engineering students, topics such as Data Definition Language (DDL) and Data Manipulation Language (DML) are crucial for understanding advanced lessons. However, learning outcomes have been low due to factors such as suboptimal media, methods, models, and teaching processes. This research aims to design reciprocal teaching-based interactive multimedia to enhance student learning outcomes in DDL and DML materials. The research method used is adapted from the Comprehensive Life Cycle model, with a sample of students from class X-RPL-1 at Bina Wisata Lembang Vocational High School.The results of this study are as follows: 1) An average percentage of 80% was obtained from media experts and 80% from subject matter experts, both categorized as “Very Good”. 2) The use of multimedia improved student learning outcomes, demonstrated by an average score increase from 34 to 73. Furthermore, based on the pretest and posttest results, an average normalized gain (n-gain) of 0.59 was obtained with a criteria of 'Moderate' effectiveness. 3) Students responses to the created multimedia resulted in an average percentage score of 86.41%, categorized as “Very Good”.

Statistical analysis of disability-adjusted life years for stomach and colorectal cancers in Changning District of Shanghai

Objectives: To analyze the status and temporal changes of disability-adjusted life year (DALY) for stomach and colorectal cancers among registered permanent residents in Changning District of Shanghai Municipality, and provide scientific basis for the prevention and treatment of stomach and colorectal cancers in this district. Methods: Using the cancer registration data of stomach and colorectal cancers from 2002 to 2019, we estimated the indices such as the DALYs, the DALY crude rates, the age-standardized DALY rates, etc. Then we used the Joinpoint regression model to calculate the average annual percent change (AAPC) and annual percent change (APC) to explore the temporal variations in different periods. Results: The DALYs of stomach and colorectal cancers in Changning District from 2002 to 2019 were 55 931 person years and 65 252 person years, respectively. The crude rates of DALY were 512.16/105 and 597.51/105, respectively. We observed a higher disease burden in men than in women, and the peak rate of DALY in stomach cancer was in the 75-79 years age group, while in colorectal cancer the rate was in the 85-years-or-older age group. Joinpoint regression analysis showed that from 2002 to 2019, the age-standardized DALY rate of stomach cancer showed a downward trend (AAPC=-3.86%, P＜0.05), while the trend of colorectal cancer was not statistically significant(AAPC=-0.08%, P＞0.05). However, the trends in the age-standardized DALY rates of colorectal cancer were different between males and females, with males showing an upward trend (AAPC=1.24%, P＜0.05) and females showing a downward trend (AAPC=-1.67%, P＜0.05). Conclusions: The DALY of stomach and colorectal cancers in Changning District of Shanghai showed a decreasing trend. Males and the middle-aged and elderly populations are still the key targets for disease prevention and control in this district.

Cognitive ability to know colour concepts through method simple science experiments in early children

Ability to know colour is one aspect of ability. It is an essential cognitive function for brain development in children at an early age. Improving the ability to know colour must supported with adequate methods and facilities, but based on conditions in the field, fewer children still understand draft colour with good Research objectives This is to increase the ability of cognitive children to know draft colour through method simple science experiment. The research used is Classroom Action Research in nature collaborative. Amount of samples from the study: This totalled 11 people. The data collection method used is sheet observation (checklist). Data analysis techniques were carried out quantitatively. Research results show that cognitive knowledge of draft colour can increase with method simple science experiments. This matter is proven by Mark's ability cognitive child with an average value of 38 with the predicate is very lacking. As for the implementation process activity method experiment For increasing cognitive child seen from teacher activities and activities, children in cycle I and Cycle II experienced enhancement that is average percentage of implementation Teacher activity in cycle I reached 67.85% with predicate sufficient, and the average percentage of implementation activity children in cycle II reached 79.85% with predicate Good. after applied activity simple science experiments, abilities know color in group B experienced enhancement from cycle I was 42.20 to cycle II amounted to 71.39 pages This prove that activity simple science experiment can improve ability cognitive child.

Novel battery power capability assessment for improved eVTOL aircraft landing

A key aspect in the deployment of electric vertical take-off and landing (eVTOL) aircraft is the safety and performance capabilities of the batteries used. A component of the safety requirements is the need for reserve energy, which would only be utilised in case of emergencies. In the literature, it has been observed that the lower bound of the reserve region of battery energy should be limited to avoid the area where a precipitous drop in voltage would occur. Here, a method for defining the lower bound is proposed. This seeks to extend the amount of time the aircraft can cruise before landing can no longer be completed. A novel power capability testing procedure is used to measure the lowest state-of-charge (SoC) at which a constant power pulse can be completed. This differs from existing power capability tests that perform pulses at predetermined SoC points. The goal of the proposed method is to replicate the conditions of landing to understand the power capability performance at low SoC. The test is performed for a variety of environmental conditions and use cases, which includes temperature and power pulses, as well as two sets of differently aged cells. For the defined test conditions, the lowest SoC values for the calendar aged cells ranges from 6% to 14% SoC, whereas the range for cycle aged cells is 8% to 27% SoC. The outcome of this test is a characteristic map which correlates temperature, pulse power and pulse duration to the lowest SoC the pulse can be completed. The characteristic map indicates the lowest SoC value allowed for the battery before landing needs to be performed. The accuracy of the characteristic map is compared to a battery equivalent circuit model, parametrised from the test data. The defined approaches are experimentally validated based on a set of previously unmeasured experimental conditions. Overall, the characteristic map provides good accuracy compared to measured values, with both map and model methods having an average maximum absolute percentage error of at most 7.5%. Additionally, the test results show that if the worst case landing scenario is used as the lower bound of the reserve region, the useable SoC range for nominal flight would be greatly affected if cell degradation is not considered.

Global prevalence and burden of multidrug-resistant tuberculosis from 1990 to 2019.

Tuberculosis(TB) remains a pressing public health challenge, with multidrug-resistant tuberculosis (MDR-TB) emerging as a major threat. And healthcare authorities require reliable epidemiological evidence as a crucial reference to address this issue effectively. The aim was to offer a comprehensive epidemiological assessment of the global prevalence and burden of MDR-TB from 1990 to 2019. Estimates and 95% uncertainty intervals (UIs) for the age-standardized prevalence rate (ASPR), age-standardized incidence rate (ASIR), age-standardized disability-adjusted life years rate (ASR of DALYs), and age-standardized death rate (ASDR) of MDR-TB were obtained from the Global Burden of Disease (GBD) 2019 database. The prevalence and burden of MDR-TB in 2019 were illustrated in the population and regional distribution. Temporal trends were analyzed by using Joinpoint regression analysis to calculate the annual percentage change (APC), average annual percentage change (AAPC) and its 95% confidence interval(CI). The estimates of the number of cases were 687,839(95% UIs: 365,512 to 1223,262), the ASPR were 8.26 per 100,000 (95%UIs: 4.61 to 15.20), the ASR of DALYs were 52.38 per 100,000 (95%UIs: 22.64 to 97.60) and the ASDR were 1.36 per 100,000 (95%UIs: 0.54 to 2.59) of MDR-TB at global in 2019. Substantial burden was observed in Africa and Southeast Asia. Males exhibited higher ASPR, ASR of DALYs, and ASDR than females across most age groups, with the burden of MDR-TB increasing with age. Additionally, significant increases were observed globally in the ASIR (AAPC = 5.8; 95%CI: 5.4 to 6.1; P < 0.001), ASPR (AAPC = 5.9; 95%CI: 5.4 to 6.4; P < 0.001), ASR of DALYs (AAPC = 4.6; 95%CI: 4.2 to 5.0; P < 0.001) and ASDR (AAPC = 4.4; 95%CI: 4.0 to 4.8; P < 0.001) of MDR-TB from 1990 to 2019. This study underscored the persistent threat of drug-resistant tuberculosis to public health. It is imperative that countries and organizations worldwide take immediate and concerted action to implement measures aimed at significantly reducing the burden of TB.

Boarding Service Governance Model in Islamic Boarding Schools in South Sulawesi Indonesia

This study aims to identify and overcome challenges in the governance of boarding services in Islamic boarding schools. The needs analysis reveals problems with dormitory facilities, including capacity, number, proficiency, and the quality of dormitory coaches. This research develops a structured HASANAH boarding service governance model by highlighting three aspects: Boarding Services, Management Principles and Quality Management, and HR/Dormitory Coach Roles. The model's validity, practicality, and effectiveness are evaluated to improve the quality of boarding school services. This research employs the Research and Development (R&amp;D) method with a systems approach consisting of four stages: (1) Preliminary study stage; (2) Model development stage; (3) Product validation and trial phase; and (4) Model production stage. Data is sourced from the results of validation of education experts and management about the content and construct of the model, as well as assessment data from cottage managers, teachers/coaches, and students about the quality of Islamic boarding school services. The instruments used are questionnaires, observation sheets, and interviews. Research data analysis techniques use quantitative and qualitative descriptive analysis. The results provide a detailed picture of development conditions and needs through average values and percentages for each aspect. Testing the validity and practicality of the model shows a high level of acceptance and usability on the part of Islamic boarding schools, supporting the conclusion that this model is valid and practical to be applied as one of the guidelines in the governance of boarding services. The evaluation of the model's effectiveness highlights its positive impact on improving the quality of boarding services. With the positive results of the trial, it can be concluded that this model is able to make a real contribution to improving aspects of boarding services in the Islamic boarding school environment. This research provides an in-depth view and potentially significant solutions to improve the governance of boarding services in South Sulawesi.