Average Increase In Body Weight Research Articles

Operative revascularization of visceral arteries in chronic mesenteric ischemia

Chronic mesenteric ischemia (CMI) is mostly the result of atherosclerotic occlusive processes of unpaired mesenteric arteries. Operative procedures are preferred in cases of occlusion of along vessel segments and/or highly calcified stenoses near the ostium. Frequently, bypasses are constucted from the aorta to visceral arteries and autologous veins should be preferred. Due to atherosclerotic alterations aortic bypass anastomoses are difficult and prone to complications. Based on case descriptions a surgical technique is presented that simplifies the aortovisceral artery bypass procedure. In all 6 patients the bypasses were open after 27months and the average increase in body weight was 13 kg within the first postoperative 6months.

Bioavailability of corn gluten meal hydrolysates and their effects on the immune system

The bioavailability of food is central to human nutrition, health and wellbeing. Here, we tested the bioavailability of hydrolysed corn gluten meal using a protein efficiency ratio method, and then analysed differences in bodyweight, weight of organs, routine blood tests and histological sections. The results indicate that the average protein intake of the hydrolysed corn gluten meal (HCGM) group was higher than that of the crude corn gluten meal (CCGM) group, and was associated with an increase in average bodyweight. The corrected protein efficiency ratios (PERs) of the HCGM and CCGM groups were 0.374 and 0.217, respectively; the corrected PER of the HCGM group was 1.72 times higher than that of the CCGM group. These results show that hydrolysis increased the bioavailability of corn gluten meal. Furthermore, there was a significant difference in organ weights (salivary gland P < 0.01; thymus gland P < 0.05; spleen P < 0.01) between the HCGM and CCGM groups. Finally, no inf lammatory cell infiltrates nor cell necrosis could be found in any of the histological sections. We speculate that hydrolysed protein preparations can improve immunity.

Productivity and slaughter index of young gees feeding of soybean lecithin and sunflower

The results of the impact of soy lecithin and sunflower on productivity and quality slaughter calves geese. Experimental studies were conducted with 200 geese breed «Danish lehart» which formed 5 groups. Since days old, I (control) group of geese received during the research period, complete feed is made in terms of private enterprise «Orbita», II, III, IV and V (experimental) group received a complete feed with the addition of its composition of different doses of lecithin sunflower instead of a similar amount of soybean meal. Experimental young geese fed complete ration that was balanced in essential nutrients. Over the entire period of growing the highest average increase in body weight observed in geese II experimental group, which was 95.2 g, which is 9.7% higher compared with the control. Advantage geese III, IV and V of experimental groups fed 0.3%, 0.4% and 0.5% soy lecithin, this indicator was 0.3%, 4.8% and 7.4% compared to analog control group. A similar trend was observed in terms of the absolute increase in body weight, where the highest increase was observed in the experimental group of geese II – 5711 g, which is 9.6% higher compared with the control. Feeding soy lecithin III, IV and V of the experimental group also tended to increase in absolute growth, namely 0.3%, 4.8% and 6.4% relative and 0.5% – 0.8%. To assess meat quality of young geese for the use of sunflower lecithin and soybean aged 60 days was held control slaughter to determine slaughtered parameters. In terms of pulp output young geese II experimental group exceeded by 16.3% (P < 0.01), analogues control group, the experimental group III geese by 4.4%, geese IV experimental group 6.4% (P < 0.05) and the experimental group geese V 8.5% respectively. By weight of skin with subcutaneous fat geese dominated research groups geese control group 12.3%, 7.1%, 5.2% and 9.9% respectively. Calculation of meat and osteal index showed that in II experimental group the figure was 1.86 and was 7.5% higher than the control at 3.5%, III research group – on 2.7%, IV group – to 1.6% and 0.5% V group respectively. Analyzing the findings can assert about the appropriateness of sunflower lecithin in the composition of complete feed young geese in an amount of 0.4%. Prospects of further research is to study the effects of different amounts and sources of sunflower lecithin in feeding breeder geese breed «Danish lehart».

Antitumor Potential of Ethyl Acetate Extract of Kirganelia reticulata Against Ehrlich Ascites Carcinoma Tumor

Kirganelia reticulata (Poir) Baill (Poir) (Euphorbiaceae) contains octacosonal, texerol acetate, berulin, sitosterol, flavonoid, tannins, glycosides, and alkaloids. It has been used as folk medicine for cancer, arthritis etc. Antitumor screening of ethyl acetate extract of Kirganelia reticulata stem (KREE) was carried out against Ehrlich ascites carcinoma tumor in Swiss albino mice at the dose of 200, 300 and 500 mg/kg, body weight. The extract was administered orally for 14 consecutive days to tumor bearing mice. The antitumor potential of KREE was assessed by evaluating increase in life span, average increase in body weight, changes in food intake, reduction in tumor volume, reduction in tumor weight, viable cell count, non-viable cell count, packed cell volume, total cell count and haematological and biochemical parameters were studied. The phytochemical analysis of extracts of K. reticulata confirmed the presence of alkaloids, flavonoid, tannins and phenolic compounds. Flavonoid content in KREE was found 3.07 ± 0.42 mg/g. The KREE inhibits the tumor growth (MIC-200 mg/kg). The viability of tumor cells decreased up to 3.9 x 107 cells in KREE treated cells (200 mg/ml). The decrease in tumor cell volume in tumor bearing mice treated with KREE doses 200, 300 and 500 mg/kg and 5- FU (20 mg/kg) was found to be 4.2 ± 0.8, 3.6 ± 1, 2.5 ± 1 and 2.4 ± 1 g respectively. The KREE increases the life span of EAC treated mice and restored the hematological parameters in a dose dependent manner.

Dietary patterns and weight change: 15-year longitudinal study in Australian adults.

Dietary intake is one of the most modifiable risk factors associated with obesity. However, data on the relationship between dietary patterns and long-term weight change are limited. We therefore investigated the association between dietary patterns and 15-year weight change in a sample of 1186 Australian adults (1992-2007). We measured body weight and collected data on socio-demographic and lifestyle characteristics in 1992 and 2007. Applying principal component analysis to 38 food groups from a food frequency questionnaire collected at baseline, we identified two dietary patterns: 'meat-and-fat' and 'fruit-and-vegetable.' Using generalized estimating equations, multivariable regression models, stratified by sex, were adjusted for concurrent changes in socio-demographic and lifestyle variables. The average increase in body weight of men in the highest tertile of the meat-and-fat pattern was more than twice that of men in the lowest tertile; mean weight change (95% CI): 4.8 (-0.1, 9.7) kg versus 2.3 (-2.6, 7.1) kg, P-for-trend=0.02. In contrast, average weight gain of men in the highest tertile of the fruit-and-vegetable pattern was only about half that of men in the lowest tertile; mean weight change (95% CI): 2.9 (-2.0, 7.8) kg versus 5.4 (-1.5, 10.4) kg, P-for-trend=0.02. Among women, dietary patterns were not related to weight change. These dietary patterns predict change in body weight in men, but not in women. In this cohort, a dietary pattern high in fruit and vegetables was related to less weight gain in men than a dietary pattern high in meat and fat.

Increased food energy supply as a major driver of the obesity epidemic: a global analysis.

ObjectiveWe investigated associations between changes in national food energy supply and in average population body weight.MethodsWe collected data from 24 high-, 27 middle- and 18 low-income countries on the average measured body weight from global databases, national health and nutrition survey reports and peer-reviewed papers. Changes in average body weight were derived from study pairs that were at least four years apart (various years, 1971–2010). Selected study pairs were considered to be representative of an adolescent or adult population, at national or subnational scale. Food energy supply data were retrieved from the Food and Agriculture Organization of the United Nations food balance sheets. We estimated the population energy requirements at survey time points using Institute of Medicine equations. Finally, we estimated the change in energy intake that could theoretically account for the observed change in average body weight using an experimentally-validated model.FindingsIn 56 countries, an increase in food energy supply was associated with an increase in average body weight. In 45 countries, the increase in food energy supply was higher than the model-predicted increase in energy intake. The association between change in food energy supply and change in body weight was statistically significant overall and for high-income countries (P < 0.001).ConclusionThe findings suggest that increases in food energy supply are sufficient to explain increases in average population body weight, especially in high-income countries. Policy efforts are needed to improve the healthiness of food systems and environments to reduce global obesity.

EVALUATION OF PHYTOCHEMICAL AND PHARMACOLOGICAL ACTIVITY OF METHANOLIC EXTRACT OF SOLANUM PUBESCENS

Traditional medicine has a long history of serving people all over the world. In recent years, the use of traditional medicine information in cancer research received considerable interest. Solanum pubescens has been used in traditional and folklore medicine for the treatment of cancer. The aim of the present study was to evaluate the effect of methanol extract of the leaves against intraperitoneally injected Dalton’s Ascitic Lymphoma (DAL) cell line in swiss albino mice. DAL cells were injected intraperitoneally (1 ×10 cells / ml / mouse) to the mice. The MESP at a dose of 100 mg / kg and 200 mg / kg body weight were administered orally for 14 consecutive days to the tumor bearing group of animals. Derived parameters, haematological parameters, serum enzyme and lipid parameters were measured and compared to the cancer control group. 5Flurouracil (20 mg / kg) was used as a standard. Both the dose of MESP decreased average increase in body weight, reduced the packed cell volume, viable tumor cell count and increased the life span of DAL treated mice and brought back the haematological parameters, serum enzyme and lipid profile near to normal values. All the values were found to be statistically significant with cancer control group at P < 0.01. These observations are suggestive of the protective effect of extracts in Dalton’s Ascitic Lymphoma (DAL). All these findings enable to conclude that MESP at 200 mg / kg dose possess a protective effect against DAL.

Clinical Effectiveness of Aripiprazole in Short-term Treatment of Tic Disorder in Children and Adolescents: A Naturalistic Study

The purpose of this study was to evaluate the effectiveness and tolerability of aripiprazole in short-term treatment of children and adolescents with tic disorder (TD). This was a 14-week, prospective, open-label flexible dose trial of aripiprazole. We enrolled patients with TD aged between 4 years and 18 years. They received aripiprazole (dose: 2.5mg/day) initially, which was then adjusted according to clinical response. The severity was assessed by the Yale Global Tic Severity Score (YGTSS) at 0, 2, 6, 10, and 14 weeks. The linear mixed models were used for evaluation of the YGTSSs at each follow-up, which were compared with baseline scores. Eighty-one patients were enrolled in this study. Nine patients withdrew from the study with complaints of adverse side effects. Of the remaining 72 patients, 15 patients discontinued medications prematurely due to being free of symptoms for over 2 weeks. Two patients discontinued medications due to no significant improvement. The mean scores had significantly decreased since the 2nd week (p<0.01). The mean reduction was 51.0% in the motor tic scores, 67.1% in the vocal tic scores, and 70.0% in the total YGTSSs. The common adverse effects were sedation (32.1%) and increased appetite (22.2%). A slight increase in average body weight was noted, from 32.7 to 33.7kg (+1.0kg, p<0.05). Aripiprazole is effective for short-term treatment of TD, especially vocal tics, in children and adolescents with mild adverse effects. However, further double-blind trials against placebo or other medications are needed to verify the efficacy of aripiprazole in the pharmacotherapy of TD.

Efficacité et tolérance de l’association ténofovir-lamivudine-éfavirenz chez les patients VIH-1 à la clinique des maladies infectieuses du CHNU de Fann à Dakar

We conducted a study to evaluate the efficacy and tolerance of the tenofovir (TDF), lamivudine (3TC) and efavirenz (EFV) combination regimen in HIV-1 patients by a descriptive analytical retrospective study of all HIV-1 patients receiving TDF-3TC-EFV combination between 2007 and 2011. Collected data was analysed using EpiInfo™ version 6.04. One hundred patients were included, with an average follow-up duration of 27 months and 19 days (± 21 months and 14 days).We observed an average increase in body weight of about 8 kg per annum, with an average rise in CD4 count of 100/mm3 by the end of the second year. A reduction in viral load with 71% of patients in therapeutic success at 24 month of treatment was noted. Ninety-two patients presented with at least one side effect, mostly being Grade 1 or 2 (96.36%). Neurological (24 patients) and digestive (20 patients) complaints comprised the commonest reported side effects. Four patients had adverse effects severe enough to warrant a change in treatment regimen, principally due to renal insufficiency. Thirteen subjects died. Patients receiving TDF-3TC-EVF combination therapy need rigorous surveillance because this combination, although efficient, is not without significant adverse effects.

Human Rights Casualties from the “War on Obesity”: Why Focusing on Body Weight Is Inconsistent with a Human Rights Approach to Health

An increase in average body weight has been the subject of intense attention from public health authorities over the past decade. The weight-centered health paradigm and resulting concerns about the “obesity epidemic” are the foundation for public health policies and programs around the world. International human rights treaties describe the legal obligations of states and the moral obligations of other actors in society to respect, protect, and fulfill human rights, including the right to health. The authors critique the weight-centered health paradigm through the lens of the Universal Declaration of Human Rights. Public health researchers and practitioners may inadvertently breach their human rights obligations by working within the weight-centered health paradigm.

Anticancer activity of aerial parts of Aerva lanata Linn Juss ex Schult against Dalton's Ascitic Lymphoma

Background and AimTraditional medicine has a long history of serving people all over the world. In recent years, the use of traditional medicine information in cancer research received considerable interest. Aerva lanata Linn Juss has been used in traditional and folklore medicine for the treatment of cancer. The aim of the present study was to evaluate the effect of methanol (known as MEAL) and aqueous extracts (known as AEAL) of the aerial parts of Aerva lanata Linn Juss against intraperitoneally injected Dalton's Ascitic Lymphoma (DAL) cell lines in Swiss albino mice. Materials and methodsDAL cells were injected intraperitoneally (1×106cells/ml/mouse) to the mice. The MEAL and AEAL at a dose of 200mg/kg body weight were administered orally for 14 consecutive days to the tumor bearing group of animals. Derived parameters, haematological parameters, serum enzyme and lipid parameters were measured and compared to the cancer control group. 5-Flurouracil (20mg/kg) was used as a standard. ResultsBoth MEAL and AEAL decreased average increase in body weight, reduced the packed cell volume, viable tumor cell count and increased the life span of DAL treated mice and brought back the haematological parameters, serum enzyme and lipid profile near to normal values. All the values were found to be statistically significant with cancer control group at p<0.01. These observations are suggestive of the protective effect of extracts in Dalton's Ascitic Lymphoma (DAL). ConclusionAll these findings enable to concluded that MEAL and AEAL possess a protective effect against DAL.

Antimelanoma and radioprotective activity of alcoholic aqueous extract of different species of Ocimum in C57BL mice

Context: Various Ocimum species (Labiateae) are commonly used for the treatment of inflammation, stress, diarrhea, and as an antioxidant drug in the Indian ethnic system of medicine.Objective: The present study was carried out to investigate the antimelanoma and radioprotective activity of different species of Ocimum in C57BL and Swiss albino mice.Materials and methods: The antimelanoma activity of 50% alcoholic aqueous leaf extract of five species of Ocimum [Ocimum sanctum (SE), Ocimum gratissimum (GE), Ocimum basilicum (BE), Ocimum canum (CE), and Ocimum kilimandscharicum (KE)] alone or in combination with radiotherapy was determined on the basis of tumor volume, body weight, and survival rate of animals. The radioprotective potential of different species of Ocimum was determined by chromosomal aberration assay. The effect of the alcoholic aqueous extract of different species of Ocimum was also evaluated for the estimation of glutathione level and glutathione S-transferase activity in Swiss albino mice.Results: The 50% alcoholic aqueous extract of different species of Ocimum administered orally (200 mg/kg, p.o.) resulted in significant reduction in tumor volume, increase in average body weight, and survival rate of mice. The various extracts showed modulatory influence against lethal irradiation doses of gamma radiation in terms of radiation-induced chromosomal damage, while at the same time induced an increase in reduced glutathione level and GST activity.Discussion and conclusion: These findings demonstrate that Ocimum species have antimelanoma and radioprotective activity against B16F10 metastatic melanoma cell line-induced metastasis and could be exploited as one of the potential sources for plant-based pharmaceutical products.

Explaining Trends in Body Weight: Offer's Rational and Myopic Choice vs Elias' Theory of Civilizing Processes

Avner Offer argues that the current increase in average body weight arises from a problem of self-control. Self-control is a central concept in Norbert Elias' theory of civilizing processes, but Offer rejects this theory as an explanation for the trend. I show in this paper that Offer's rejection of this theory is based on invalid arguments. Furthermore, considering the empirical data, I demonstrate that the new environment of abundance is not accompanied by a general decline in self-control, as Offer argues, but leads to a differentiated increase in new forms of self-control, as can be explained by Elias' theory. Like Offer, I argue for an explanation for the trends in body weight from an anthropometric historical perspective. The starting point, however, should be social differentiation. Finally, I clarify the concept of self-control, as this is a debated issue.

Antitumor Activity of Prosopis glandulosa Torr. on Ehrlich Ascites Carcinoma (EAC) Tumor Bearing Mice.

The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPG at the dose of 100, 200 and 400 mg/Kg, significantly (p < 0.001) increased the survival time and decreased the average body weight of the tumor bearing mice. After 14 days of inoculation, EPG was able to reverse the changes in the hematological parameters, protein and PCV consequent to tumor inoculation. Oral administration of EPG was effective in reducing solid tumor mass development induced by EAC cells. The results indicate that EPG possess significant antitumor activity on dose dependent manner.

Rifaximin diminishes neutropenia following potentially lethal whole-body radiation

Terrorist attacks involving radiological or nuclear weapons are a substantial geopolitical concern, given that large populations could be exposed to potentially lethal doses of radiation. Because of this, evaluating potential countermeasures against radiation-induced mortality is critical. Gut microflora are the most common source of systemic infection following exposure to lethal doses of whole-body radiation, suggesting that prophylactic antibiotic therapy may reduce mortality after radiation exposure. The chemical stability, easy administration and favorable tolerability profile of the non-systemic antibiotic, rifaximin, make it an ideal potential candidate for use as a countermeasure. This study evaluated the use of rifaximin as a countermeasure against low-to-intermediate-dose whole-body radiation in rodents. Female Wistar rats (8 weeks old) were irradiated with 550 cGy to the whole body and were evaluated for 30 d. Animals received methylcellulose, neomycin (179 mg/kg/d) or variably dosed rifaximin (150-2000 mg/kg/d) one hour after irradiation and daily throughout the study period. Clinical assessments (e.g. body weight) were made daily. On postirradiation day 30, blood samples were collected and a complete blood cell count was performed. Animals receiving high doses of rifaximin (i.e. 1000 or 2000 mg/kg/d) had a greater increase in weight from the day of irradiation to postirradiation day 30 compared with animals that received placebo or neomycin. For animals with an increase in average body weight from irradiation day within 80-110% of the group average, methylcellulose rendered an absolute neutrophil count (ANC) of 211, neomycin rendered an ANC of 334, rifaximin 300 mg/kg/d rendered an ANC of 582 and rifaximin 1000 mg/kg/d rendered an ANC of 854 (P = 0.05 for group comparison). Exposure to rifaximin after near-lethal whole-body radiation resulted in diminished levels of neutropenia.

Risks and Benefits of an Open Irrigation Tip Catheter in Intensive Radiofrequency Catheter Ablation in Patients With Non-Paroxysmal Atrial Fibrillation

Although open irrigation tip catheters (OITC) are effective in producing transmural radiofrequency (RF) lesions, they have the potential for fluid overload or excessive tissue damage. The 203 patients with non-paroxysmal atrial fibrillation (NPAF; 85.2% males, 55.2+/-10.6 years old) who underwent RF catheter ablation (RFCA) were analyzed retrospectively. Clinical outcomes and complications were compared between RFCA using OITC (n=92) and that using conventional catheters (CONC; n=111). Both the total procedure time (P<0.01) and fluoroscopic time (P<0.001) were shorter in the OITC group than in the CONC group. Total fluid loading during RFCA with OITC was 3.2+/-0.9L, and the average body weight increase was 1.8+/-1.2 kg. Symptomatic pulmonary edema and/or pleural effusion occurred in 3.3% of patients who had a bigger left atrium (P=0.005), longer duration of ablation procedure (P=0.002), higher post-RFCA serum pro-ANP level (P<0.001), and longer hospitalization (P<0.01). RFCA for NPAF using OITC results in a shorter procedure time compared with CONC. However, patients with a large left atrium and a large amount of fluid (>4L) infused via the OITC need to be carefully monitored to prevent pulmonary edema or pleural effusion because of fluid overload.

Insulin‐induced weight gain and cardiovascular events in patients with type 2 diabetes. A report from the DIGAMI 2 study

We investigated whether insulin treatment-induced weight gain was accompanied by increased cardiovascular (CV) mortality and morbidity in the second Diabetes Insulin Glucose in Acute Myocardial Infarction (DIGAMI 2) study. We studied the 865 patients who survived during 12 months without any change in their glucose-lowering (GL) therapy. They were divided into four subgroups according to GL treatment: group I, no pharmacological GL treatment (n = 99); group II, oral hypoglycaemic agents (n = 250); group III, new insulin treatment (n = 245) and group IV, insulin before inclusion continued during the first year of follow up (n = 271). Patients who started on insulin (group III) experienced an average body weight increase of 2.3 (1.5-3.2) kg during the first year of treatment, whereas weight remained unchanged in groups I, II and IV. The incidence of non-fatal reinfarction was higher in group III compared with the other groups (hazard ratio (HR) = 2.5, p = 0.011) and CV mortality was higher in group IV (HR = 2.4, p = 0.003). When the subjects were grouped in quartiles according to maximal body weight increase, those in the lowest quartile experienced the highest CV mortality. Each kilogram increase in weight reduced the risk for CV death with 6%. The incidence of reinfarction did not differ between quartiles. Initiation of insulin treatment after myocardial infarction was associated with a significant increase in weight and incidence of reinfarction. The increase in weight did, however, not explain the increased rate of reinfarction.

A Model for Chronic Osteomyelitis Using Staphylococcus aureus in Goats

Animal models of osteomyelitis traditionally have been characterized by inherent weaknesses related to animal size, differences in clinical findings compared with humans, aggressive behavior, high complication rate, and high cost. In this experiment, a model of tibial osteomyelitis was established in 28 goats with a very low complication rate and a consistent clinical, radiographic, and histologic disease course. The infecting Staphylococcus aureus organism was isolated in all but five of 28 animals (82%), in which there was no growth of bacteria at 24 and 72 hours. All five of these specimens had histologic evidence of osteomyelitis. Twenty-seven of the 28 animals (96%) had radiographic and histologic evidence of osteomyelitis. Clinical progression of the disease was observed by draining wounds, a postoperative limp that subsided in all goats, and varied periods of anorexia despite an average increase in body weight. There were no complications or mortalities related to the establishment of the animal model. This large animal model will provide a practical method of studying osteomyelitis and comparing treatment protocols.

Anterior pituitary corticotropes of adrenalectomized, leptin-administered rats.

Leptin (LEP), the product of the ob gene is an adipose-tissue secreted hormone that acts to decrease caloric intake and increase energy expenditure. Some observations suggest the mutual relationship between leptin and blood ACTH levels. In the rat acute LEP administration enhances blood ACTH levels while prolonged treatment lowers blood corticotropin concentrations. Since the pituitary-derived ACTH is an important element in functioning of that loop, studies were undertaken to investigate the effect of prolonged LEP administration on anterior pituitary ACTH cells of adrenalectomized rats. Studies were performed on bilaterally adrenalectomized adult female rats. They were administered for 3 or 6 days with 2.7 nmol/rat/day LEP (recombinant human leptin) or with the vehicle (0.9% NaCl). LEP administration did not affect the body weight of bilaterally adrenalectomized rats. During the whole experiment the average increase in body weight was 3.9-4.3 g/day. LEP administration into adrenalectomized rats had no effect on anterior pituitary weight. This treatment resulted in a significant increase in pituitary ACTH concentration and content, and these changes were accompanied by a potent decrease in blood corticotropin level. LEP administration into adrenalectomized rats only insignificantly lowered the quantity of anterior pituitary ACTH-immunoreactive cells and their average area. On the opposite, the average volume of pituitary corticotropes of LEP-treated rats was notably lower than that in adrenalectomized-vehicle administered ones. Results of performed experiments clearly demonstrate that prolonged LEP administration results in a notable inhibition of the growth and secretory activity of anterior pituitary corticotropes of the adrenalectomized rats.

ESTUDO COMPARATIVO DAS ANASTOMOSES ARTERIAIS COM FIO ABSORVÍVEL E NÃO ABSORVÍVEL EM SUÍNOS EM CRESCIMENTO

O objetivo deste trabalho foi observar a evolução, após 12 meses, das artérias anastomosadas com polipropileno e com fios de poliglactina 910, nos suínos em fase de crescimento. A amostra foi composta por 16 fêmeas da raça Landrace, distribuídas em dois grupos : A e B. Os animais devidamente pesados, foram submetidos a secção transversal da aorta abdominalis, abaixo das arteriae renalis dextra et sinistra,que após a medida dos diâmetros internos foram anastomosadas com os fios correspondentes, mediante suturas contínuas. Após um ano os animais foram submetidos à eutanásia e novas medidas realizadas. Em ambos os grupos ficou evidenciado que pesos maiores estão relacionados a diâmetros maiores das artérias. Houve aumento médio de 1027,5 % no peso final dos animais do grupo A e 1242,9 % nos animais do grupo B. Houve aumento médio de 98,6 % no diâmetro final das artérias dos animais do Grupo A e de 102,7% nas animais do grupo B. Para a análise estatística valeu-se dos testes de WILCOXON e MANN-WHITNEY, com cálculo de &lt;FONT FACE="Symbol"&gt;D&lt;/FONT&gt; %. Os fios de polipropileno permaneceram nas artérias dos animais do grupo A sendo identificados de duas formas: rotos ou em alça, mas sempre fazendo proeminência na luz arterial. Os fios de poliglactina 910 não foram identificados. Concluiu-se que o fios de polipropileno e de poliglactina 910 permitem o crescimento das artérias ao nível das anastomoses término-terminais na aorta abdominalis de suínos.