Abstract Objective: To assess the perception of nurse managers about the application of TQM (Total Quality Management) at Assiut University Hospitals. Subjects and Methods: Research design: A descriptive analytical study design was used to collect data from study subjects. Setting: Data were collected from seven Assiut University hospitals. The Subjects: All nurse managers working at Assiut University Hospitals (n= 393). The instrument : Self-administered questionnaires developed by the researcher were used to collect data, it consists of two parts: First part: nurses managers’ personal characteristics information, and Second part: include TQM application practices which divided into 8 practices (74 items). Results: Nurse managers participated in the study perceived that TQM practices are not applied at Assiut University Hospitals. Nurse managers have low level of knowledge about TQM, Nurse managers seek to apply quality to: increase productivity, increase satisfaction, decrease cost, minimize errors, The majority of nurse managers supporting the application of TQM at Assiut University Hospitals, There is a positive correlation between TQM application practices, hospital, educational qualification, and negative correlation between years of experience and TQM application practices. Conclusions: Assiut University Hospital managers must focus their on increasing nurses knowledge and skills to apply TQM at hospital effectively and efficiently. Recommendations: Design an official quality structure for the central quality department, Distributing the quality culture among all hospital personnel through posters, booklets, symposiums, quality magazine, and videos, Preparing a training plan for all nursing personnel to increase their knowledge and skills about TQM. Design an operational plan to implement TQM practices.
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