This study investigates and analyses alternative materials for replacing the femur bone in the human body, addressing the critical need for bio-implant materials arising from injuries, diseases, or natural deterioration. The femur, as the largest and strongest bone, is indispensable for mobility and weight support. Surgical intervention often necessitates the replacement of damaged femurs with suitable bio-implant materials. Using the Analytic Hierarchy Process (AHP), this study selects optimal materials considering corrosion resistance, biocompatibility, Young's modulus, fatigue strength, and tensile strength—to replace the femur. A geometric model of the femur bone is constructed using a modelling package, enabling finite element analysis (FEA) to evaluate the endurance and suitability of selected bio- implant materials. The FEA is conducted on two materials—stainless steel and titanium alloy—to assess their performance as femur replacements. Through comprehensive analysis, this research aims to contribute insights into the efficacy and viability of alternative bio-implant materials for femur bone replacement.