Alderson Phantom Research Articles

ABSORBED DOSE AND DOSE RATE USING THE VARIAN OBI 1.3 AND 1.4 CBCT SYSTEM

According to published data, the absorbed dose used for a CBCT image acquisition with Varian OBI v1.3 can be as high as 100 mGy. In 2008 Varian released a new OBI version (v1.4), which promised to reduce the imaging dose. In this study, absorbed doses used for CBCT image acquisitions with the default irradiation techniques of Varian OBI v1.3 and v1.4 are measured. TLDs are used to derive dose distributions at three planes inside an anthropomorphic phantom. In addition, point doses and dose profiles inside a 'stack' of three CTDI body phantoms are measured using a new solid state detector, the CT Dose Profiler. With the CT Dose Profiler, the individual pulses from the X-ray tube are also studied. To verify the absorbed dose measured with the CT Dose Profiler, it is compared to TLD. The image quality is evaluated using a Catphan phantom. For OBI v1.3, doses measured in transverse planes of the Alderson phantom range between 64 mGy and 144 mGy. The average dose is around 100 mGy. For OBI v1.4, doses measured in transverse planes of the Alderson phantom range between 1 mGy and 51 mGy. Mean doses range between 3-35 mGy depending on CBCT mode. CT Dose Profiler data agree with TLD measurements in a CTDI phantom within the uncertainty of the TLD measurements (estimated SD +/- 10%). Instantaneous dose rate at the periphery of the phantom can be higher than 20 mGy/s, which is 10 times the dose rate at the center. The spatial resolution in v1.4 is not as high as in v1.3. In conclusion, measurements show that the imaging doses for default modes in Varian OBI v1.4 CBCT system are significantly lower than in v1.3. The CT Dose Profiler is proven fast and accurate for CBCT applications.

Absorbed and effective doses from cone beam volumetric imaging for implant planning

Volumetric CT using a cone beam has been developed by several manufacturers for dentomaxillofacial imaging. The purpose of this study was to measure doses for implant planning with cone beam volumetric imaging (CBVI) in comparison with conventional multidetector CT (MDCT). The two CBVI systems used were a 3D Accuitomo (J. Morita), including an image-intensifier type (II) and a flat-panel type (FPD), and a CB MercuRay (Hitachi). The 3D Accuitomo operated at 80 kV, 5 mA and 18 s. The CB MercuRay operated at 120 kV, 15 mA, 9.8 s. The MDCT used was a HiSpeed QX/i (GE), operated at 120 kV, 100 mA and 0.7 s, and its scan length was 77 mm for both jaws. Measurement of the absorbed tissue and organ doses was performed with an Alderson phantom, embedding the radiophotoluminescence glass dosemeter into the organs/tissues. The values obtained were converted into the absorbed dose. The effective dose as defined by the International Commission on Radiological Protection was then calculated. The absorbed doses of the 3D Accuitomo of the organs in the primary beam ranged from 1-5 mGy, and were several to ten times lower than other doses. The effective dose of the 3D Accuitomo ranged from 18 muSv to 66 muSv, and was an order of magnitude smaller than the others. In conclusion, these results show that the dose in the 3D Accuitomo is lower than the CB MercuRay and much less than MDCT.

Dose reduction by automatic exposure control in multidetector computed tomography: comparison between measurement and calculation

The aim of this study was to investigate the potential of dose reduction in multidetector computed tomography (MDCT) by current-modulated automatic exposure control (AEC) and to test the reliability of the dose estimation by the conventional CT dosimetry program CT-EXPO, when an average tube current is used. Phantom measurements were performed at a CT system with 64 detector rows for four representative examination protocols, each without and with current-modulated AEC. Organ and effective doses were measured by thermoluminescence dosimeters (TLD) at an anthropomorphic Alderson phantom and compared with those given by the calculation with CT-EXPO. The application of AEC yielded dose reductions between 27 and 40% (TLD measurements). While good linearity was observed between measured and computed effective dose values both without and with AEC, the organ doses showed large deviations between measurement and calculation. The dose to patients undergoing a MDCT examination can be reduced considerably by applying a current-modulated AEC. Dosimetric algorithms using a constant current-time product provide reliable estimates of the effective dose.

Experimental validation of Monte Carlo calculations with a voxelized Rando–Alderson phantom: a study on influence parameters

The development and improvement of techniques for an accurate dose assessment in medical physics is an important task. In this study, we focus on the validation of Monte Carlo calculations, by comparing organ doses assessed experimentally with thermoluminescent detectors in the Rando–Alderson phantom with doses calculated for a voxelized model of the same phantom for some typical x-ray procedures. A detailed study has been performed to identify the key parameters that affect the determination of organ doses. Initially, TLD measurements were up to 65% higher than the calculated values. After the corrections made on TLD energy dependence, TLD angular dependence, material composition and field size and position, most differences between measurements and calculations are within 15%. For organs far away from the field the difference is about 30%.

Comparison between effective radiation dose of CBCT and MSCT scanners for dentomaxillofacial applications

Objectives To compare the effective dose levels of cone beam computed tomography (CBCT) for maxillofacial applications with those of multi-slice computed tomography (MSCT). Study design The effective doses of 3 CBCT scanners were estimated (Accuitomo 3D ®, i–CAT ®, and NewTom 3G ®) and compared to the dose levels for corresponding image acquisition protocols for 3 MSCT scanners (Somatom VolumeZoom 4 ®, Somatom Sensation 16 ® and M×8000 IDT ®). The effective dose was calculated using thermoluminescent dosimeters (TLDs), placed in a Rando ® Alderson phantom, and expressed according to the ICRP 103 (2007) guidelines (including a separate tissue weighting factor for the salivary glands, as opposed to former ICRP guidelines). Results Effective dose values ranged from 13 to 82 μSv for CBCT and from 474 to 1160 μSv for MSCT. CBCT dose levels were the lowest for the Accuitomo 3D ®, and highest for the i-CAT ®. Conclusions Dose levels for CBCT imaging remained far below those of clinical MSCT protocols, even when a mandibular protocol was applied for the latter, resulting in a smaller field of view compared to various CBCT protocols. Considering this wide dose span, it is of outmost importance to justify the selection of each of the aforementioned techniques, and to optimise the radiation dose while achieving a sufficient image quality. When comparing these results to previous dosimetric studies, a conversion needs to be made using the latest ICRP recommendations.

Accuracy of three-dimensional (3D) craniofacial cephalometric landmarks on a low-dose 3D computed tomograph

The aim of this paper is to compare the accuracy of cephalometric landmark identification using three-dimensional CT (3D-CT) surface rendering with "high-dose" (200 mAs) and "low-dose" (35 mAs) CT protocols. The absorbed dose levels for radiosensitive organs in the maxillofacial region during the exposure for both 3D-CT protocols were also measured. The study population consisted of 15 human dry skulls examined with spiral 3D-CT. 12 cephalometric anatomical landmarks at 7 sites were identified on the 3D-CT surface renderings by 2 observers independently, twice each, using high-dose and low-dose protocols. In total, 1440 imaging measurements were made. Thermoluminescent dosemeters (TLDs) were placed at ten sites around the thyroid and submandibular glands and the eyes in an Alderson phantom for measuring the absorbed dose levels. The intraobserver mean distances between 3D landmarks were smaller for all sites with the high-dose protocol (P = 0.37). There was a significant difference among the observers (P = 0.000004). Interobserver mean distances between 3D landmarks were smaller for four of the seven sites with the low-dose protocol. However, the global interobserver mean distances between 3D landmarks for all sites were smaller with the high-dose protocol (P = 0.028). The low-dose protocol reduced the radiation dose to the thyroid by 6.12, to the submandibular salivary glands by 5.91 and to the eye by 5.44, resulting in a global reduction factor of 5.71. The accuracy in the landmark's identification was maintained when the milliampere-second values were reduced from 200 mAs to 35 mAs. We recommend use of the low-dose protocol for clinical 3D-CT cephalometric applications.

Assessment of the effective dose for routine protocols in conventional CT, electron beam CT and coronary angiography

To compare the effective dose applied by sequential CT (SEQ), spiral CT (SCT), electron beam CT (EBT) and coronary angiography for investigations of the chest, abdomen and the heart. The Alderson Phantom was used to compare the effective dose for all modalities. In addition, the effective dose for conventional CT (SEQ and SCT) was estimated with a mathematical phantom. For CT investigation of the chest and abdomen the dose was highest for the EBT (11 mSv and 25 mSv, respectively) and slightly lower for the SEQ (7.8 mSv and 21.5 mSv, respectively), whereas spiral CT required the least dose (5.3 mSv and 8.8 mSv, respectively). For coronary calcium screening (0.8 mSv) and EBT coronary angiography (1.7 mSv) the dose was lower than for coronary catheter angiography (3.3 mSv). For conventional CT the difference between the effective dose derived by the mathematical phantom and by the Alderson phantom was 2% to 20%. For investigations of the chest and abdomen the effective dose applied by SCT is significantly lower than that with EBT and SEQ. For investigation of the coronary arteries the effective dose applied by EBT is lower than that for coronary catheter angiography.

Factors influencing the absorbed dose in intraoral radiography

The aim of the present study was to find out whether it was more effective to achieve a dose reduction in intraoral radiography with an increase in the tube potential setting (and a decrease of milliampere seconds) by an additional attenuation of the X-ray beam behind the film plane or by the use of digital radiography. A second aim was to find out if there were differences between the integral doses determined by two different detectors and two different phantoms. The X-ray attenuation in this in vitro study was carried out using additional lead foils from the dental film packet fixed behind the film plane and with a metal film holder. The dose measurements were performed with two semiconductor detectors (Quart, Diados). Patient simulation was achieved by the Alderson phantom or by the use of a filter (6Al+0.8Cu). The absorbed doses were calculated by integrating an exponential function between the entrance dose and the body exit dose. In addition, organ doses were measured and the effective dose was determined according to the Implementation of the 1990 Recommendations of the ICRP (ICRP-60). The increase in tube potential levels did not provide a substantial reduction of the absorbed dose (90 kVp instead of 60 kVp: reduction to 92.4%), only a reduction of the entrance dose (by 30% to 35% at 90 kVp compared with 60 kVp). The use of three lead foils behind the film plane instead of one resulted in a 14.0% reduction of the absorbed dose (60 kVp); the use of a metal film holder resulted in a 27.8% reduction (60 kVp). When tube potential settings were increased, the dose reduction decreased. The absorbed dose was reduced to 52% when a storage phosphor plate was used instead of a film (60 kVp). It was possible to determine the amount of dose reduction with both the calculated absorbed dose and the effective doses. The integral doses obtained from the Alderson phantom showed values 5% higher than those obtained by the filter (r(2)=96.7%). For the comparison of the integral doses, the measurements performed with Quart had values higher by a factor of 1.139 than those performed with Diados. Instead of increasing the tube voltage or using additional lead foils or metal film holders, a substantial dose reduction is provided by digital radiography or more sensitive films while a low tube potential level is maintained and the milliampere seconds setting is reduced.

X-ray and gamma-ray absorbed dose profiles in teeth: An EPR and modeling study

Dose profiles in teeth have been experimentally and theoretically studied for different energies and geometries of incident X- and gamma-rays. The experiments were conducted with teeth inside of an Alderson phantom using monodirectional radiation beams at selected energies; they revealed two effects: an apparent lack of dose attenuation between the buccal and the lingual sides of the teeth for energies higher than 120 keV and an attenuation between first and last tooth layers for low-energy beams in the range from 0.28 to 0.57. Monte Carlo simulations confirmed the experimental data and provided dose profiles for other energies and geometries. In particular, exposure in the rotational radiation field produces pronounced dose profiles only for energies lower than 60 keV. The usefulness of these data to estimate the average energy of accidental radiation field is discussed.

Possibilities of dose reduction in lateral cephalometric radiographs and its effects on clinical diagnostics

The aim of the present study was to determine (1) the absorbed and the exit radiation doses for cephalometric exposures on a phantom head with various exposure settings and image receivers, and (2) the diagnostic image quality for various modalities assessed on cephalometric radiographs of patients. The dose measurements for lateral cephalometric radiographs were performed with a semiconductor detector, and also with thermoluminescent detectors and an Alderson phantom. Both the integral and the effective doses were determined. Two radiographs of each patient (n=119) were taken at two different times, one at a low tube potential setting, 75+/-5 kV, and one with a decreased dose. Film-screen systems with speed class 400 and one storage phosphor plate were used. Five observers assessed the radiographs for the visualization of six cephalometric reference points on a three-point scale with -1, 0 and 1. Twenty-seven image pairs were rescored to determine inter- and intrarater reliability. The statistical analysis was done using analysis of variance and Tukey's HSD (honestly significant difference) post hoc test. Increasing the tube potential setting led to an average dose reduction to 83% (integral dose) or to 87% (effective dose). Instead of taking the radiograph at a low tube potential setting (75 kV), a dose reduction of about 15% was feasible at a high tube potential setting (90 kV). A significant difference in reference point visibility existed between film radiographs at low tube potential settings (mean score 0.984) and at high tube potential settings (90 kV, mean score 0.958). For the storage phosphor plates, there was no significant difference to the film-screen combinations at low tube potential and halved milliampere seconds settings. In the second assessment, there was a high degree of agreement (96.6%) compared with the first assessment (unadjusted for random agreement). As there is only minimal dose reduction at increased tube potential settings, for a dose reduction, it seems to be more useful to use storage phosphor plates at unchanged tube potential and halved milliampere seconds settings compared with the film-screen combination.

Optimizing the tube potential for lumbar spine radiography with a flat-panel digital detector

The purpose of this study was to find the optimal settings for lumbar spine radiography with a flat-panel detector. A CDRAD contrast-detail phantom was imaged at various tube potentials, system speeds and filtration settings. Factorial experiments yielded a range of optimized exposure settings, which were submitted to visual grading analysis with images of an Alderson phantom. The first optimized settings involved a system speed increase from 400 to 800. For anteroposterior projection, the optimal tube potential was reduced from the default of 77 kV to 60 kV to give the best image quality without increasing the effective dose, or to 66 kV to give the lowest dose without reducing image quality. For lateral projection, the tube potential was similarly reduced from the default of 90 kV to 70 kV or 77 kV. Visual grading analysis confirmed the results, with significantly better image quality when optimizing for image quality. The study thus shows that the tube potential can be reduced as long as the system speed is increased simultaneously. This leads to a lower effective dose and/or increased image quality depending on the settings chosen. The factorial experiments provided a powerful way to evaluate several parameters concomitantly.

Strahlenexposition bei der 3D-Rotationsangiographie des Schädels

Determination and comparison of radiation exposure for examinations of the skull with unsubtracted 3D Rotational Angiography (3D RA) and 2D Digital Subtraction Angiography (2D DSA). Measurements were carried out with a skull of an Alderson phantom for 3D RA and for 2D DSA in p. a. and lateral projections using an Innova 4100 angiography system with a digital flat panel detector from GE Healthcare. 45 thermoluminescent dosimeters TLD 100H from Harshaw were placed inside the phantom to measure organ doses. In addition the dose area product was recorded and the effective dose was calculated using the Monte Carlo program PCXMC. For a biplanar DSA run (lateral and p. a. projection), the organ doses were 4 to 5 times higher and the effective dose was 4 times higher than for a 3D RA even though the number of images for the two DSA runs was only half of that for 3D RA. The radiation exposure for unsubtracted 3D RA using a flat panel detector is significantly lower than for biplanar DSA. Using 3D RA in place of 2D DSA can reduce the radiation exposure of patients in neuroradiology procedures.

SU‐FF‐T‐299: Investigation of Near Surface Doses in Mesothelioma Intensity Modulated Radiation Therapy

Purpose: To investigate the measured and computed near surface doses for intensity modulated radiation therapy (IMRT) of mesothelioma. The near surface dose value is important since in most cases the intent is to deliver about 90% of the prescribed dose to the surgical scar region. Material and Methods: Two planning CT scans (3mm slice thickness) of a humanoid Alderson phantom with 5 mm and 10 mm bolus placed on the thoracic region were acquired with our Philips CT scanner. At the time of CT, opaque markers are placed under bolus to designate 10 different locations throughout thoracic region for calculations and measurements. IMRT plans are generated using the Nucletron OTP treatment planning system. IMRT calculations are performed for a 3 mm × 3 mm calculation grid and inhomogeneity correction with pencil beam algorithm. Plans are delivered to the phantom with a Siemens Oncor linac. Doses are measured at each marked location under each bolus, mimicking depths of 5 mm and 10 mm, using a pair of LiF thermoluminescence dosimeters (TLD). Results: The average dose difference between the measured and calculated data at depth of 5 mm is 8.6% with percent differences ranging from 3.6% to 18.3%. For the points at 10 mm depth this average is about 2.7 % and the percent difference range is 0.1% to 4.7%. Conclusion: Our results indicate that dose calculated for mesothelomia IMRT cases at depth of 5mm show a larger uncertainty relative to the measurements than dose calculated at deeper depth of 10 mm for OTP. The measurements show good agreement at 10 mm depth; on average, results are within accuracy of the TLD measurements (within 3%). It is therefore important for patient treatment to carefully evaluate the near surface dose (i.e.5 mm depth) via measurements.

Optimierung des Strahlenschutzes für das Personal in der Radiologie auf Grundlage der effektiven Dosis

In the present study the optimization of radiation protection devices is achieved by minimizing the effective dose of the staff members since the stochastic radiation effects correlate to the effective dose. Radiation exposure dosimetry was performed with TLD measurements using one Alderson Phantom in the patient position and a second phantom in the typical position of the personnel. Various types of protective clothing as well as fixed shields were considered in the calculations. It was shown that the doses of the unshielded organs (thyroid, parts of the active bone marrow) contribute significantly to the effective dose of the staff. Therefore, there is no linear relationship between the shielding factors for protective garments and the effective dose. An additional thyroid protection collar reduces the effective dose by a factor of 1.7 - 3.0. X-ray protective clothing with a 0.35 mm lead equivalent and an additional thyroid protection collar provides better protection against radiation than an apron with a 0.5 mm lead equivalent but no collar. The use of thyroid protection collars is an effective preventive measure against exceeding occupational organ dose limits, and a thyroid shield also considerably reduces the effective dose. Therefore, thyroid protection collars should be a required component of anti-X protection.

Variation of DaTSCAN quantification between different gamma camera types

To acquire data from a 123I filled Alderson phantom on different gamma cameras types and compare the relative uptake results from processing using the QuantiSPECT program (GE Healthcare). A DaTSCAN phantom was filled using the standard protocol and imaged on seven different gamma camera types and on two identical cameras of the same type. The standard GE Healthcare protocols for the given cameras were used. Aliquots of the striatum and brain background were counted in a gamma counter to determine variations in filling concentration. All the raw DaTSCAN SPECT data was imported into QuantiSPECT and processed by the three different algorithms (two box, three box and crescent) to determine the relative uptake in the striatum. Inter-operater and intra-operator variation was also determined. The 10% variation in filling concentration found across the sites was compensated for in the final results. There was a 5-15% variation between cameras depending on the processing algorithm used. There was an intra-operator variation of between 5 and 12% which reflected the proportion of operator intervention within the processing method. There was no statistical variation between operators. The transfer of a DaTSCAN database between camera types is feasible, but ideally all data would be acquired on a single camera type and phantom data used to normalize the database accordingly.

Radiation exposure in stent-grafting of abdominal aortic aneurysms

In recent years, endovascular stent-grafting of abdominal aortic aneurysms has become more and more common. The radiation dose associated with these procedures is not well documented however. The aim of the present study was to estimate the radiation exposure and to simulate the effects of a switch from C-arm radiographic equipment to a dedicated angiographic suite. Dose-area product (DAP) was recorded for 24 aortic stent-grafting procedures. Based on these data, entrance surface dose (ESD) and effective dose were calculated. A simulation of doses at various settings was also performed using a humanoid Alderson phantom. The image quality was evaluated with a CDRAD contrast-detail phantom. The mean DAP was 72.3 Gy cm(2) at 28 min fluoroscopy time with a mean ESD of 0.39 Gy and a mean effective dose of 10.5 mSv. If the procedures had been performed in an angiographic suite, all dose values would be much higher with a mean ESD of 2.9 Gy with 16 patients exceeding 2 Gy, which is considered to be a threshold for possible skin injury. The image quality for fluoroscopy was superior for the C-arm whilst the angiographic unit gave better acquisition images. Using a C-arm unit resulted in doses similar to percutaneous coronary intervention (PCI). If the same patients had been treated using dedicated angiographic equipment, the risk of skin injury would be much higher. It is thus important to be aware of the dose output of the equipment that is used.

Varied tube potential with constant effective dose at lumbar spine radiography using a flat-panel digital detector

The purpose of the study was to evaluate the image quality at different tube potential (kV) settings using anteroposterior lumbar spine radiography as a model. An Alderson phantom was used with a flat-panel detector. The tube potential varied between 48 and 125 kV while the tube charge (mAs) was adjusted to keep an effective dose of 0.11 mSv. Image quality was assessed with a visual grading analysis and with a CDRAD contrast-detail phantom together with a computer program. The VGA showed inferior image quality for the higher kV settings, > or =96 kVwith similar results for the contrast-detail phantom. When keeping the effective dose fixed, it seems beneficial to reduce kV to get the best image quality despite the fact that the mAs is not as high as with automatic exposure. However, this cannot be done with automatic exposure, which is set for a constant detector dose.

Application of commercial MOSFET detectors for in vivo dosimetry in the therapeutic x-ray range from 80 kV to 250 kV

The purpose of this study was to investigate the dosimetric characteristics (energy dependence, linearity, fading, reproducibility, etc) of MOSFET detectors for in vivo dosimetry in the kV x-ray range. The experience of MOSFET in vivo dosimetry in a pre-clinical study using the Alderson phantom and in clinical practice is also reported. All measurements were performed with a Gulmay D3300 kV unit and TN-502RDI MOSFET detectors. For the determination of correction factors different solid phantoms and a calibrated Farmer-type chamber were used. The MOSFET signal was linear with applied dose in the range from 0.2 to 2 Gy for all energies. Due to fading it is recommended to read the MOSFET signal during the first 15 min after irradiation. For long time intervals between irradiation and readout the fading can vary largely with the detector. The temperature dependence of the detector signal was small (0.3% °C−1) in the temperature range between 22 and 40 °C. The variation of the measuring signal with beam incidence amounts to ±5% and should be considered in clinical applications. Finally, for entrance dose measurements energy-dependent calibration factors, correction factors for field size and irradiated cable length were applied. The overall accuracy, for all measurements, was dominated by reproducibility as a function of applied dose. During the pre-clinical in vivo study, the agreement between MOSFET and TLD measurements was well within 3%. The results of MOSFET measurements, to determine the dosimetric characteristics as well as clinical applications, showed that MOSFET detectors are suitable for in vivo dosimetry in the kV range. However, some energy-dependent dosimetry effects need to be considered and corrected for. Due to reproducibility effects at low dose levels accurate in vivo measurements are only possible if the applied dose is equal to or larger than 2 Gy.

Emergency localization of radioactive seeds lost during intracoronary brachytherapy.

Recently, it has been reported that brachytherapy catheters ruptured in vivo. Localization of lost beta-radiation-emitting seeds is a problem because no appropriate technique is available that is rapid and precise. We developed a technique to localize beta-emitting seeds utilizing the effect that beta-radiation induces bremsstrahlung. The loss of a single radioactive source was simulated in an Alderson Phantom representing a human body. The beta-induced bremsstrahlung could be detected selectively by a gamma-camera. The position of the radioactive seed could be located within 5 min with an accuracy of +/- 0.5 cm. The result of this study suggests that in an emergency case of loss of a brachytherapy source, a commercially available gamma-camera can be a valuable tool to detect lost beta-radiation-emitting seeds rapidly and precisely. In addition, the technique minimizes the patient's as well as the surgeon's exposure to radiation and reduces the extent of surgical trauma.

Assessment of a theoretical formalism for dose estimation in CT: an anthropomorphic phantom study.

Dose assessment in computed tomography (CT) is challenging due to the vast variety of CT scanners and imaging protocols in use. In the present study, the accurateness of a theoretical formalism implemented in the PC program CT-EXPO for dose calculation was evaluated by means of phantom measurements. Phantom measurements were performed with four 1-slice, four 4-slice and two 16-slice spiral CT scanners. Firstly, scanner-specific nCTDIw values were measured and compared with the corresponding standard values used for dose calculation. Secondly, effective doses were determined for three CT scans (head, chest and pelvis) performed at each of the ten installations from readings of thermoluminescent dosimeters distributed inside an anthropomorphic Alderson phantom and compared with the corresponding dose values computed with CT-EXPO. Differences between standard and individually measured nCTDIw values were less than 16%. Statistical analysis yielded a highly significant correlation (P < 0.001) between calculated and measured effective doses. The systematic and random uncertainty of the dose values calculated using standard nCTDIw values was about -9 and +/- 11%, respectively. The phantom measurements and model calculations were carried out for a variety of CT scanners and representative scan protocols validate the reliability of the dosimetric formalism considered-at least for patients with a standard body size and a tube voltage of 120 kV selected for the majority of CT scans performed in our study.