Abstract
The Use of Cryopreserved Autologous Mononuclear Bone Marrow Cells for the Treatment of Non-Healing Ulcers in Diabetic Foot Syndrome
Highlights
The diabetic foot syndrome (DFS) is one of the most serious forms of complications of diabetes mellitus
The emergence of DFS contributes to a number of reasons such as ischemia of the lower extremities, neuropathy, traumatic and infectious effects
DFS epidemiology is appears to be quite complex as there are no single criteria for assessing the condition and diagnostic tests
Summary
The diabetic foot syndrome (DFS) is one of the most serious forms of complications of diabetes mellitus. The emergence of DFS contributes to a number of reasons such as ischemia of the lower extremities, neuropathy, traumatic and infectious effects. Diabetic vascular disturbances lead to long-term non-healing ulcers and often the only way to cure them is amputation. DFS epidemiology is appears to be quite complex as there are no single criteria for assessing the condition and diagnostic tests. It is noted that the prevalence of DFS significantly differs in different population groups. It is believed that in Western countries about 2% of the population with diabetes mellitus suffers from long-lasting non-healing ulcers. According to other estimates the risk of the DFS emergence reaches 25% during lifetime in such patients [3]
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