Abstract
Investigating the Wound Healing Potential of Costus afer (Ker Gawl) Stem Juice on Cutaneous Wounds of Albino Rats
Highlights
The process of wound healing involves a complex cascade of cellular and biochemical mechanisms aiming at the restoration of the structural and functional integrity with regain of strength of the injured tissues or organs
Phytochemical analysis showed that Costus afer stem juice extract contained biomolecules that have been found to promote wound healing, such as alkaloids, saponin, flavonoids, triterpene, quinones, lignans and stilbenes (Table 2)
The result of the study showed that Costus afer stem juice extract enhanced the healing process
Summary
The process of wound healing involves a complex cascade of cellular and biochemical mechanisms aiming at the restoration of the structural and functional integrity with regain of strength of the injured tissues or organs. It is brought about by cell-cell and cellmatrix interactions that signal the process through three overlapping phases of inflammation, proliferation and tissue remodeling [1,2]. It has been suggested that an ideal wound management should aim to maintain a moist wound environment, while limiting loss of fluid, shield the wound from further damage, remove necrotic debris, promote granulation tissue formation, relieve pain and protect the wound from bacterial contamination [3,6,7]
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