The pathological analysis of 213 children with ocular tumor

Abstract

To analyze the pathological classification of ocular tumor in children. 213 cases (214 eyes) of ocular tumor in children below 14 years old between January 2001 and December 2007 in Henan Eye Institute were reviewed retrospectively, the pathological classification were made according to the location and nature of the tumor. There were 17 eyes (7.94%) of 214 eyes with benign tumor of eyelid, the leading two tumor were 4 eyes with cyst, in which 1 eye with epidermoid cyst and 3 eyes with dermoid cyst were included, and 3 eyes with squamous papilloma. There were 84 eyes (39.25%) of 214 eyes with conjunctival and corneal tumor, 1 eye with intraepithelial tumor was found, other tumors were all benign tumor, the leading three tumors were corneal dermoid (64 eyes), conjunctival nevus (10 eyes) and squamous papilloma (4 eyes). There were 73 eyes (34.11%) with intraocular tumor including 66 eyes (90.41%) with retinoblastoma, 6 eyes (8.22%) with iris cyst and 1 eye (1.37%) with iris melanoma. Of 38 eyes of orbital tumor, cyst (16 eyes), vascular hamartoma (7 eyes) and inflammatory pseudotumor (4 eyes) were the most common benign tumors, there were 3 eyes (7.89%) with orbital extension of retinoblastoma and 2 eyes (5.26%) with rhabdosarcoma. There were 2 eyes with scleral tumor, including 1 eye with scleral bony choristoma and 1 eye with congenital scleral cyst. Altogether, there are 135 eyes (63.08%) with benign tumor and 79 eyes (36.92%) with malignant tumors. Most children's ocular tumors are congenital and embryonic tumors. Retinoblastoma is the most common malignant ocular tumor in children, then is corneal dermoid.