Clinical analysis of 141 cases of ocular surface tumors

Abstract

Objective To access the classification clinical features and misdiagnosis of ocular surface tumors. Methods A retrospective study of 141 patients with ocular surface tumors admitted to Tianjin Eye Hospital from March 2002 to November 2009 was undertaken. All of them were comfirmed by histopathologicai biopsy. Clinical records including pathological types, site of lesions and clinical characteristics. Results One hundred and seventeen of 141 tumors were benign, and the most frequent tumors included cyst (29 cases,24.7%), sebaceoma (22 cases, 18.8%), nevus (12 cases, 10.2%); 24 of 141 cases were malignant, the most frequent tumors were lymphadenoma (7 cases, 29.1%), malignant melanoma (6 cases, 25.0%), intraepithelial neoplasm (5 cases, 20.8%). There were 72 (51.1%) cases of tumors exsiting bulbar conjunctiva, which was the most common location. The other sites included fornical conjunctiva (30 cases, 21.3%), limbal (13 cases,9.2%), palpebral conjunctiva (12 cases, 8.5%), inner canthus (10cases, 7.1%), caruncle (4 cases, 2.8%). Three cases of pigmented nevus were misdiagnosed as malignant melanoma; 2 cases of intraepithelial neoplasm were difficult to distinguish from squamous cell carcinoma; 2 cases of sebaceoma were hard to differentiate from dermoid cysts. It could not be differentiated clinically between benign and malignant lymphoid tumors. Conclusions Some of the ocular surface tumors can be misdiagnosed because clinical features are similar, especially secondary conjunctival tumors and mucoepidermoid carcinoma ofconjunctiva whose incidence are much lower than others. Raise awareness of them will contribute to the correct diagnosis. Key words: Ocular surface tumors; Benign; Malignant; Diagnose