Clinical and pathological analysis of ocular tumor in 410 children cases

Abstract

Objective To explore the classification,distribution and pathogenetic characteristics of ocular tumor in children. Methods Retrospective analysis was taken in age,tumor location and pathological types of 410 children with ocular tumor recruited from Shanxi eye hospital in the year 2000-2010 periods. Results The mean age was 7.08±2.6 years old in all cases.There was significant difference in age of onset among intraocular tumor children comparing to other place tumor by holding on 2.44±1.5 years old (F =15.658,P =0.001).In terms of tumor location,the first two common lesion location were conjunctiva and orbit with 152 (37.1％) and 84 (20.5％) respectively.Among all cases there were 362 (88.3％) benign tumors and 48 (11.7％) malignant ones.The most popular benign tumor was dermoid cyst contributing to 72 (19.9％) followed by dermoid tumor 63 (17.4％),dermatolipoma,57 (15.7％) and papilloma 33 (9.1％),etc.The retinoblastoma held the largest percentage of malignant tumors in children ocular with 43 (89.6％) and followed by rhabdomyosarcoma with 2 (4.2％),etc. Conclusions Ocular tumors in children mainly are congenital and embryonic tumors.The most common ocular tumor in 410 children patients is the conjunctival tumor.Dermoid cysts present the highest prevalence in benign ocular tumor followed by papilloma,inflammatory hyperplasia and epithelium cysts.Among the malignant tumors,retinoblastoma shows the highest prevalence and the age of onset in malignant tumors much younger than benign ocular tumor. Key words: Children; Ocular tumor; Pathological analysis