Abstract
THIS PAPER emphasizes certain ocular factors which, by reducing the intensity of the retinal stimulus from a test object, may cause simulated progression of the visual field defects of glaucoma and thereby give misleading information regarding the glaucomatous state. Some pertinent clinical and experimental observations are presented. The factors investigated by us were changes in transparency of the ocular media, refractive disturbances, and miosis. All these conditions diminish the amount of light falling upon a given area of the retina from a given test object. The size of any visual field defect which might be present therefore increases correspondingly. Emphasis on the effects of these factors upon the visual field changes of chronic simple (wide-angle) glaucoma is of great importance because visual field studies offer the most reliable method of evaluating the effectiveness of medical therapy. Likewise, progressive enlargement of visual field defects serves as the best and most dependable
Published Version
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