Abstract
Reinke’s edema, polyps and nodules of the vocal folds, belong to the exudative lesions of the Reinke’s space (EPPR), have common features of pathogenesis, are similar in etiology, morphogenesis and clinical manifestations, but have a characteristic topography of the location on the vocal folds. Cellular elements of both the lamina propria, the subepithelial zone, and the connective tissue take part in maintaining tissue and immune homeostasis. The study of the morphometric features of EPPR in representatives of vocal professions was the aim of the work. Microscopic studies in 47 tissue samples were performed on a DMRXA microscope (Leika, Germany) using the Image Scope M program (Germany). Statistical processing of the material was carried out using the Statistica 10.0 for Windows software package. Our data showed a number of features of the cellular composition and stromal component in various EPPRs. The tissues of angiomatous polyps and vocal nodules contained a large number of fibroblasts and had a high specific area of the vasculature. In tissue samples of myxoid polyps and with Reinke’s edema, a significant increase in the number of lymphocytes, histiocytes, the height of the epithelial layer and the specific area of the fluid component of the connective tissue was shown. The absence of an inflammatory process was indicated by the minimum content of all ESPR of neutrophils and macrophages in the tissues.
Published Version
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