Abstract
West Nile virus belongs to the Flaviviridae family, transmitted by vector mosquitoes. Here, we reported the complete genome sequence of West Nile virus isolated from human samples during an acute encephalitis outbreak in Kerala, India. Phylogenetic analysis revealed that the virus genome clusters into genetic lineage 1, clade 1a.
Highlights
West Nile virus belongs to the Flaviviridae family, transmitted by vector mosquitoes
We reported an outbreak of acute encephalitis syndrome (AES) from May through July 2011 in Kerala, India
Among 208 AES cases, 69 (33%) were in patients belonging to the pediatric age group and 139 (66.82%) were in adults
Summary
West Nile virus belongs to the Flaviviridae family, transmitted by vector mosquitoes. The virus belongs to the genus Flavivirus Japanese encephalitis antigenic complex, in the Flaviviridae family. The seroprevalence of WNV antibodies in a population indicated the presence of this virus in India [1, 2]. WNV isolates from mosquito, bat, and human specimens confirmed the circulation of this virus in India [3]. Phylogenetic analysis of the partial genome indicated that Indian isolates of WNV belong to genetic lineage 1 (clade 1c) [4].
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