Abstract
ABSTRACTVibrio cholerae is a Gram-negative waterborne human pathogen and the causative agent of cholera. Here, we present the complete genome sequence of the seventh pandemic O1 biovar El Tor Inaba strain A1552 isolated in 1992. This clinical strain has served as an important model strain for studying cholera pathogenicity traits.
Highlights
Vibrio cholerae is a Gram-negative waterborne human pathogen and the causative agent of cholera
A whole-genome-derived phylogeny identified other O1 El Tor strains as closest relatives, including the Inaba model strain N16961 [18, 20, 21]
For virulence and resistance profiling, A1552 gene and protein inventories were queried against V. cholerae virulence and resistance databases [22, 23]
Summary
Vibrio cholerae is a Gram-negative waterborne human pathogen and the causative agent of cholera. Hybrid assembly yielded two circular high-coverage (125ϫ and 112ϫ) chromosomes [18] with genome sizes of 3,015,092 bp and 1,0703,71 bp and GC contents of 47.7% and 46.9% for chromosomes 1 and 2, respectively, in accordance with findings for other V. cholerae O1 genomes [18].
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