Abstract

To the Editor: Vibrio cholerae O1, a causative agent of cholera, was classified into 2 biotypes, classical and El Tor (1). However, accumulating evidence suggests that atypical El Tor V. cholerae, which possesses traits of both classical and El Tor biotypes, has replaced the seventh pandemic prototypic El Tor V. cholerae worldwide in recent years. Cholera outbreaks in Thailand during 2007–2010 were caused by atypical El Tor isolates carrying the classical type cholera toxin gene (2). Epidemiologic surveys in a Thailand–Myanmar border area during 2008 yielded more than 500 isolates of V. cholerae O1. We identified an isolate that possessed the typical El Tor type cholera toxin gene (genotype 3) and designated it MS6 (later assigned strain number DMST28216). It does not belong to either the seventh pandemic prototypic biotype identified in 1961 or the group of atypical El Tor strains found during 1991–present (3).

Highlights

  • Sauvage V, Cheval J, Foulongne V, Ar Gouilh M, Pariente K, Manuguerra JC, et al Identification of the first human gyrovirus, a virus related to chicken anemia virus

  • Cholera outbreaks in Thailand during 2007–2010 were caused by atypical El Tor isolates carrying the classical type cholera toxin gene [2]

  • We identified an isolate that possessed the typical El Tor type cholera toxin gene and designated it MS6

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Summary

Introduction

Author affiliation: Unités Mixtes de Recherche Centre National de la Recherche Scientifique 7268 Equipe “Emergence et coévolution virale,” Marseille, France 2. Sauvage V, Cheval J, Foulongne V, Ar Gouilh M, Pariente K, Manuguerra JC, et al Identification of the first human gyrovirus, a virus related to chicken anemia virus. 7. Chu DK, Poon LL, Chiu SS, Chan KH, Ng EM, Bauer I, et al Characterization of a novel gyrovirus in human stool and chicken meat.

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