Abstract
There are different routes a chemical can use to be eliminated from the body. Chemicals can be excreted in feces, urine, and exhaled breath. In this chapter, an overview of physiological processes that are involved is given, followed by a review of the different physiologically based pharmacokinetic (PBPK) models that were developed to estimate these types of excretion and/or the concentration of chemicals in the mentioned excreta.
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