Abstract
Enzymes in human plasma can be measured to provide important information about diseases. The circulating levels of relative tissue-specific enzymes and their isoforms are used as markers of tissue injury. In addition, nonenzymatic proteins and smaller peptides in circulation have been invaluable in the differential diagnosis of tissue injury. This chapter describes the use of certain enzymes in human plasma as markers in the diagnosis and prognosis of disorders, tissue dysfunction, and/or damage. Also, uses of enzymes in the quantification of other enzymes, metabolites, and drugs are discussed along with their use as therapeutic agents in the treatment of diseases.
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