Abstract
Exosomes and other extracellular vesicles (EVs) play a fundamental role in intracellular communication during bacterial infections. EVs can carry both host and bacterial components that upon uptake by target cells can induce a host protective response or further the survival and spread of the bacterial pathogen. However, despite significant work on the content and function of EVs, we still have only a limited understanding of how these vesicles modulate the immune response in vivo. Nevertheless, in recent years we have seen a significant increase in publications on EVs during bacterial infections; the results of which are highlighted in this chapter.
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