Abstract
This chapter reviews the current understanding of chemical and biochemical mechanisms of metabolism of warfare nerve agents describing the role of the enzymes involved in this process. Among enzymes participating in metabolism of nerve agents, the roles of A-esterases, serum cholinesterase, carboxylesterase, prolidase, and lipase are discussed. This chapter also discusses other aspects of metabolism of the agents, such as protein binding and the role of tissue depots for these compounds.
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