Abstract

Presented in this chapter are data on the principal hydrolysis products of Russian VX (VR) with excess and equimolar quantities of water. A highly selective gas chromatography technique was developed in order to monitor compliance with hygienic regulations in the Russian Federation. This consisted of a conversion of VR to fluorohydride on a tablet impregnated with silver fluoride, followed by thermal desorption of fluorohydride into a gas chromatograph from a sorption tube. A unified method of direct determination of VR and its conversion products in various matrices with HPLC-MS/MS technique is described. Data on environmental monitoring of VR are presented, as well as data on effects developed under chronic exposure of rats to VR, including kinetic parameters of blood platelet aggregation and electrophysiology of the nervus tibialis.

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