Abstract

In recent years, the number of biomedical applications of nanoparticles has grown exponentially. Hyperthermia using magnetic nanoparticles under the application of magnetic fields represents a promising tool for treating tumors and can be considered as a favorable substitute to conventional chemical medicine for curing various cancer diseases. Many nanoparticles with specific electric, magnetic, acoustic, optical, or thermal features have been applied to induce hyperthermia, pointing for a substantial improvement of the treatment efficiency. For the successful application of this method, it is necessary to make use of and/or to boost the heating efficacy of magnetic nanoparticles. Here, we discuss some principles for effective magnetic nanoparticles focusing on the magnetic heating mechanism. Some limitations for practical use of magnetic hyperthermia, together with preclinical and clinical applications, are briefly presented.

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