Analysis of prognostic factors on ultrasound guided radiofrequency ablation in the treatment of primary hepatic carcinoma

Abstract

Objective To explore the clinical efficacy and related factors on ultrasound guided radiofrequency ablation in the treatment of primary liver cancer. Methods This retrospective study involed the patients admitted between December 2012 and July 2015.A total of 130 patients who underwent radiofrequency ablation.111 of 130 patients were followed up.The clinical efficacy was summarized and the prognostic factors was analyzed. Results The survival rate of less than 2 years was 35.1%,the survival rate of more than 2 years was 64.9%.By the single factor analysis,gender,age,hepatitis history,splenomegaly or hypersplenism,preoperative aspertate aminotransferase,preoperative alanine aminotransferase,preoperative total bilirubin and preoperative prothrombin time were not obvious influence on survival,there was no statistically significant difference(P>0.05). Child grading,lcirrhosis of liver,liver function,serum albumin,alphafetoprotein,tumor number,a single tumor diameter and the total diameter of the largest influence on patient survival was statistically significant(P<0.05). By the multifactor analysis,the maximum diameter of single tumor and serum albumin were independent prognostic factors of radiofrequency ablation. Conclusion Radiofrequency ablation is an effective treatment for liver cancer,the treatment effect is influenced by many factors.Through the analysis of related factors,it is helpful to select a better indications for clinical treatment and improve the prognosis of hepatic carcinoma. Key words: Radiofrequency ablation; Primary hepatic carcinoma; Prognosis; Related factors