Research progress on radiofrequency ablation combined with other interventional techniques for treatment of primary liver cancer

Abstract

The mortality rate of primary liver cancer (HCC) ranks third in the world, while the annual incidence and mortality of hepatocellular carcinoma patients in China are more than 50% of the global average. At present, surgery is still the only method that may cure HCC, but the majority of patients have no chance of surgery when found to be in the advanced stage. In recent years, interventional minimally invasive treatment has become one of the hotspots for the treatment of unresectable liver cancer, including transcatheter arterial chemoembolization (TACE) , local ablation therapy, brachytherapy between radioactive particles, and high-intensity focused ultrasound in vitro. Due to the variety of interventional minimally invasive treatment methods, how to use rational and orderly joint application is still the current research hotspot. This article mainly focuses on the new advances in the application of various interventional integrated techniques based on radiofrequency ablation for the treatment of liver cancer. Key words: Primary liver cancer; Radiofrequency ablation; Transcatheter arterial chemoembolization; Interventional integrated technique