Abstract
Introduction: Coronavirus primarily affects the respiratory organ and results in respiratory symptoms. However, this newly emergent virus is not entirely known; therefore, not all symptoms are defined yet. Several reports have shown that the virus has a tendency to infect the central nervous system. In this report, we present a patient with COVID-19 and concurrent neurological presentation who was positive for lung CT scan and positive anti-COVID-19 antibody.
Highlights
Coronavirus primarily affects the respiratory organ and results in respiratory symptoms
Early therapeutic anticoagulation with LMWH could be considered as a beneficial approach to reduce thromboembolism, but must be balanced against the risk of intracranial haemorrhage, including haemorrhagic transformation of the acute infarct
Polymerase chain reaction (PCR) analysis of the cerebrospinal fluid (CSF) samples were positive for SARS-CoV-2, which has shown that the virus has the potential to cross the blood-brain barrier [4,5]
Summary
We recommend to follow-up the patient and keep on taking atorvastatin and anti-platelete medications (aspirin, plavix) beside risk factor evaluation, for patients with the same situation. Early therapeutic anticoagulation with LMWH could be considered as a beneficial approach to reduce thromboembolism in ischaemic stroke patients with COVID-19 infection, but must be balanced against the risk of intracranial haemorrhage, including haemorrhagic transformation of the acute infarct. Future studies with more cases are needed to assess prognostic factors
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