Abstract
Conventional chemotherapeutic drugs cause severe adverse effects during clinical uses. A compact delivery vehicle triggered to release its payload in the tumor microvasculature without affecting healthy tissues which could be a very likely to improve the therapeutic window of any anticancer drug. Sugar-based hydrogels possess an inherent ability to respond toward environmental stimuli. These types of bioinspired hydrogels are capable of mimicking the native tumor microenvironment by generating three-dimensional tumor models which are emerging hotspots in modern cancer research. Therefore, they have very promising applications both for fundamental cancer research as in vitro tumor model and for anticancer drug screening. This chapter is specifically themed to give a glimpse of the different approaches developed using hydrogels to study various aspects of cancer biology. The primary aim is to motivate researchers toward the design and synthesis of novel stimuli-responsive sugar-derived bioinspired hydrogels for making next-generation smart materials.
Published Version
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