This study analyzed the existing global experience of university and labor market partnerships concerning the employment of youth with disabilities. It was found that current cooperation models are implemented locally, in a fragmented manner, and are limited to interactions between universities and large enterprises. The research aimed to explore the current state of meeting the needs of students with disabilities in terms of providing educational services and employment opportunities and to analyze the interaction between universities, municipalities, and the labor market to improve employment opportunities for young people with disabilities. The study considered a survey of three target groups from different regions of Ukraine (105 students with disabilities, 321 university faculty members, and 102 enterprise managers) conducted to study the current state of needs satisfaction in providing educational services and employing people with disabilities. The findings indicated a lack of coordination among stakeholders, an absence of systematization, and organization in addressing the issue of improving the employment of youth with disabilities. The research enabled the identification of existing and desired connections between the subjects of social partnership. A social partnership model between universities, municipalities, and the labor market was developed to improve the employment of youth with disabilities. The study results are promising, as implementing the social partnership model will broadly impact society.