The article presents the results of the study on unfavourable locations for animals’ anthrax registered in the Republic of Sakha (Yakutia) conducted from 2010 to 2018. The research materials were archival documents of the veterinary service of the Yakutsk region, including written reports from the fi rst veterinarians to the Governor of the region about outbreaks of anthrax among domestic animals and people, statistics on the incidence and mortality rate of anthrax in domestic animals from 1811 to 1993, and data from the census of the population and animals. This work was carried out to compile the cadastre of stationary unfavourable locations for anthrax. During the study period, 739 outbreaks of anthrax among domestic and wild animals in 29 administrative districts and 244 settlements were recorded on the territory of the Republic. Among them, there were 455 unfavourable locations that were not previously included in the Russian Cadastre. The information presented in the cadastre of unfavourable locations for animals’ anthrax includes the name of the settlement and farm (given the administrative and territorial changes of districts, settlements and farm names), the year of registration, the number of unfavourable locations and the animal species. As a basis for compiling this cadastral map, geographical maps of the administrative and territorial divisions of the districts were used. These maps show unfavourable locations with signs and use cartographic, statistical and other methods applied in epizootology and epidemiology. The study of stationary unfavourable locations on the territory of the Republic of Sakha (Yakutia) has gained particular importance in recent decades. This was facilitated by the intensive development of the country’s economy, accompanied by large-scale development of deposits of diamond, gold, oil, gas, and the construction of railways and Lena and Kolyma federal roads. The construction works take place in the areas including the ones adjacent to stationary unfavourable locations, which therefore requires an assessment of their epidemiological risk. The cadastre of unfavourable locations for animals’ anthrax will enable specialists of Rospotrebnadzor, veterinary and design institutions, employees of the Ministry of Emergencies, municipalities of districts and settlements to develop and implement a set of preventive measures in places unfavourable for anthrax.