On 6 February 2023, two 7.8 magnitude earthquakes consecutively hit south-central Türkiye, causing great concern from all governments, the United Nations, academia, and all sectors of society. Analyses indicate that there is also a high possibility of strong earthquakes with a magnitude of 7.8 or above occurring in the western region of China in the coming years. China is a country that is highly susceptible to catastrophic disasters such as earthquakes, floods, and other natural calamities, which can cause significant damages to both human life and property, as well as widespread impacts on the society. Currently, China’s capacity for disaster prevention and control is still limited. In order to effectively reduce the impact of catastrophic disasters, ensure the safety of people’s lives and property to the greatest extent possible, maintain social stability in high-risk areas, and ensure high-quality and sustainable regional development, it is urgent to improve the seismic resistance level of houses and critical infrastructure in high earthquake risk zones and increase the earthquake-resistant design level of houses in high-risk fault areas with frequent seismic activities; significantly enhance the ability to defend against extreme weather and ocean disasters in economically developed areas along the southeastern coast, as well as the level of fortification in response to extreme meteorological and hydrological disasters of coastal towns/cities and key infrastructure; vigorously enhance the emergency response capacity and disaster risk prevention level in western and ethnic minority regions; comprehensively improve the defense level of residential areas and major infrastructure in high geological hazard risk zones with flash floods, landslides, and mudslides; systematically promote national disaster prevention and mitigation education; and greatly enhance the societal disaster risk reduction ability, including catastrophic insurance.