Weak Cation Exchange Resin Research Articles

Relative adrenaline content in brain tissue.

AbstractFollowing chromatographic separation on a weak cation exchange resin (Amberlite IRC 50) adrenaline was identified in the brains of hens, pigs and rats by means of 1) the ethylene diamine condensation method, 2) the trihydroxyindole method and 3) bioassay on the hen's rectal caecum and cat's blood pressure. The percentage adrenaline in these species varied from 4,5 to 17. In brains of oxen and guinea pigs no adrenaline was detected, indicating less than 4 per cent adrenaline in these species.

Ion Exchange Resin Dye Compounds for Use in Indirect Determination of Gastric Acidity

The results of a systematic in vitro investigation of the ion exchange resin dye com-pounds are reported. The indicators were selected for their readily recognizable colors. Representative combinations of resins and indicators were prepared and evaluated. A typical procedure for 1 of 21 compounds prepared is presented. An improved in vitro evaluation technique is outlined, and in vitro elution studies made of 8 classical types of resin indicator compounds are presented. The compound type most nearly conforming to stated requirements consisted of a weak cation exchange resin combined with a strong base indicator. Carboxylic cation exchange resins are suitable for use in tubeless tests for gastric acidity. No suitable dye was found.