Abstract
The results of a systematic in vitro investigation of the ion exchange resin dye com-pounds are reported. The indicators were selected for their readily recognizable colors. Representative combinations of resins and indicators were prepared and evaluated. A typical procedure for 1 of 21 compounds prepared is presented. An improved in vitro evaluation technique is outlined, and in vitro elution studies made of 8 classical types of resin indicator compounds are presented. The compound type most nearly conforming to stated requirements consisted of a weak cation exchange resin combined with a strong base indicator. Carboxylic cation exchange resins are suitable for use in tubeless tests for gastric acidity. No suitable dye was found.
Published Version
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