Treatment of edema with cation exchange resins, including certain hormonal observations.

Abstract

Article1 April 1954TREATMENT OF EDEMA WITH CATION EXCHANGE RESINS, INCLUDING CERTAIN HORMONAL OBSERVATIONSLEO H. T. BERNSTEIN, M.D., Ph.D., JOHN M. EVANS, M.D.LEO H. T. BERNSTEIN, M.D., Ph.D.Search for more papers by this author, JOHN M. EVANS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-4-698 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe use of ion exchange resins was suggested by Segal et al.2for control of gastric acidity and by Dock3for treatment of cardiac edema. The background and theory of ion exchange by resins in vitro and in vivo have been well elucidated.1, 4-22In some 250 reported cases of edema of chronic cardiac decompensation,23-37hepatic cirrhosis,27-38, 40pregnancy39and nephrosis,41, 42a large proportion responded well to resin therapy. Some of the patients have received continuous resin medication for as long as a year. The daily dietary intake of sodium varied from 0.2 gm. up to 8.0 gm. and...Bibliography1. AdamsHolmes BAEL: Adsorption properties of synthetic resins, J. Soc. Chem. Industry, London, Trans. Sec. 54: 1-6, 1935. Google Scholar2. SegalHodgeWatsonScottCoate HLHJSMJHA: A polyamine-formaldehyde resin. 1. Its effect upon the pH of acidified solutions and the pH and pepsin of gastric juice in vitro. 2. Its toxicity in rats, Gastroenterology 4: 484-500, 1945. Google Scholar3. Dock W: Sodium depletion as a therapeutic procedure; the value of ion-exchange resins in withdrawing sodium from the body, Tr. A. Am. Physicians 59: 282-285, 1946. Google Scholar4. BoydSchuburtAdamson GEJAW: The exchange adsorption of ions from aqueous solutions by organic zeolites. 1. Ion-exchange equilibria. 2. Kinetics of ionic exchange adsorption processes, J. Am. Chem. Soc. 69: 2818-2829, 2836-2848, 1947. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 25, 1953.From The Department of Medicine, The George Washington University Medical School, Washington, D. C.Supported in part by a Research Grant, National Heart Institute, National Institutes of Health, United States Public Health Service.†Trainee in Cardio-Vascular Diseases of The National Heart Institute, National Institutes of Health, United States Public Health Service. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAdsorption and release studies of cefuroxime sodium from acrylic ion exchange resin microparticles coated with gellanTherapie der HerzinsuffizienzVerschiedene Arzneimittel 1 April 1954Volume 40, Issue 4Page: 698-710KeywordsCardiovascular diseasesCationsEdemaHeartHeart diseasesMedical servicesPrevention, policy, and public healthResearch grantsSodium ePublished: 1 December 2008 Issue Published: 1 April 1954 PDF downloadLoading ...