Wave Irradiation Research Articles

Modulation of Voltage-Gated Calcium Influx by Electromagnetic Irradiation With Terahertz Gaussian Pulse

The voltage-gated calcium influxes modulated with terahertz Gaussian pulse is presented in this paper, and temperature rise is evaluated to monitor the terahertz thermal effects involved in the modulation. From the numerical results, inhibition effect on voltage-gated calcium influx because of the loss of the influx from electric drift is transparently revealed in the modulation with terahertz Gaussian pulse. And the inhibition effect becomes significant reflected by considerable reduction in voltage-gated calcium influx as the irradiated amplitude is raised intense enough. Compared to the terahertz sinusoidal wave, Gaussian pulse reduces the inhibition effect dramatically. The decrease in the increment of intracellular calcium concentration with the irradiated amplitude due to the inhibition effect is substantially relieved by the modulation of the calcium influx with terahertz Gaussian pulse. The thermal analyses reveal that the modulation is non-thermal effect. Meanwhile, to raise the intracellular calcium concentration to a same amount by means of the voltage-gated calcium influx, application of terahertz Gaussian pulse induces much less concurrent temperature rise than application of terahertz sinusoidal wave of the same amplitude that is intense enough to cause the inhibition effect. Additionally, terahertz Gaussian pulse irradiation remains the dependence of the increment of the calcium concentration on the irradiated time duration and frequency in terahertz sinusoidal wave irradiation. These numerical results lay the theoretical basis for the modulation of voltage-gated calcium fluxes with terahertz Gaussian pulse and for further potential clinical applications of terahertz Gaussian pulse.

An Equivalent Scattering Method for a Novel Cellular Medium

A new novel structure is proposed for cellular composite radar absorbing materials, and an equivalent method of electromagnetic scattering for the new material is also proposed for the first time. By covering the target surface with non-uniform medium cellular cell elements horizontally, the scattering characteristics of the coated target show strong surface anisotropy, leaving an imaginary space for optimizing the electromagnetic stealth performance of the coated target. In this paper, the equivalent dielectric tensor of horizontal directional composite honeycomb cell element has been calculated by using the equivalent method of electromagnetic scattering based on strong fluctuation theory (SFT) of anisotropic medium. Under the condition of plane wave irradiation with a frequency of 3 GHz, we use FEKO software to estimate the backscatter field of several typical models coated with this new structure. It has been proved that the strong fluctuation theory applied to the honeycomb composite absorbing material of the structure are effective for calculating the equivalent scattering. Based on the validity of the equivalent results, we further estimate the scattering characteristics of complex targets coated with the novel cellular medium.

Method screening for conjugation of the small molecules onto the vinyl-coated Fe3O4/silica nanoparticles: highlighting the efficiency of ultrasonication

Method development for surface functionalization of vinyl-coated iron oxide nanoparticles via [4 + 2] one-pot cycloaddition is presented in this work. Small molecules are loaded onto the surface of silica-coated magnetic nanoparticles (Fe3O4/SiO2 NPs) by various methods. The main factors such as surface modification ratio, core/shell structure maintenance, spherical morphology preservation and particle size uniformity were precisely investigated by various analyses. In this regard, reflux, microwave and ultrasound wave irradiation have been well compared as three different effective methods for carrying out the cycloaddition (CA) reactions onto the surface of magnetic nanoparticles. Overall, it was concluded that the safer and faster method for this purpose is implemented by the ultrasound wave irradiation.

Pulsed 450 nm blue light significantly inactivates Propionibacterium acnes more than continuous wave blue light

Infection with Propionibacterium acnes is ubiquitous, and drug resistant strains have been on the rise as the use of pharmaceutical antimicrobials continues to engender the emergence of further resistant strains. In previous studies, we showed that treatment with blue light serves as an alternative to pharmaceutical intervention. As a part of our ongoing effort to improve the antimicrobial efficacy of blue light, we studied the effect of pulsed 450 nm light on P. acnes in vitro and compared two pulsed rates with continuous wave irradiation. We irradiated cultures of P. acnes at various irradiances and radiant energies either singly or repeatedly at various time intervals, using printed micro-LEDs, with the goal of finding the lowest combination of irradiance and radiant energy that would yield 100% bacterial suppression. Our results show that treatment with 33% pulsed light gave the best result compared to 20% pulsed wave or continuous wave. Timing irradiation to coincide with the replication cycle of P. acnes produced a significantly better antimicrobial effect. Furthermore, repeated irradiation at 3-h or 4-h interval enabled significant bacterial suppression even at lower irradiances; thus, making single irradiation at high irradiances unnecessary. Moreover, combining repeated irradiation with appropriate duration of treatment and 33% irradiation pulse rate gave optimal 100% [7 log10] bacterial suppression.

Real-time visualization of instantaneous frequency from bubble cavitation using color Doppler ultrasound imaging

Time-resolved observations of acoustic cavitation emission signals are important in understanding bubble cavitation dynamics and monitoring sonoporation efficiencies of ultrasound-assisted drug delivery systems. Previous methods using back propagation of such signals measure frequencies with high time resolutions but require post-processing. We propose a method using color Doppler ultrasound to obtain instantaneous frequencies of these signals from the phase differences with an external reference signal. Standard color Doppler processing is applied to both emissions and reference signals to enable real-time observations of bubble cavitation generated by high-intensity ultrasound wave irradiation. A sinusoidal wave signal was used to confirm the accuracy of our method with an estimation error of 8.59%. Experiments were performed using Sonazoid suspensions of two different concentrations. With a sound pressure of 1.0 MPa for the ultrasound wave, the type of bubble cavitation that is dominant is different before and after irradiation of about ten pulses.

The effects of early treadmill training combined with ultrashort wave irradiation on functional recovery from spinal cord injury

Objective To investigate the effect of early-stage training combined with the ultrashort wave therapy on the functional recovery of rats after a spinal cord injury, and to observe the expression of aquaporin protein-4 (AQP-4) and glial fibrillary acidic protein (GFAP). Methods Fifty female Sprague-Dawley rats had spinal cord injury (SCI) induced using the modified Allen′s method. After successful modeling, 40 were randomly divided into a sham operation group, a control group, an ultrashort wave group, a treadmill group and a combined group, each of 8. Motor function in their hind limbs was evaluated 4 weeks after the operation using BBB scoring. GFAP and AQP-4 immunohistochemical staining were used to determine the integral optical density (IOD) of the protein expression. Results The average BBB score of the sham operation group was 21, while the other four groups averages were all less than 1 on the 1st day after the operation. They gradually increased with time, and by 4 weeks the increases were significant. Compared with the control group at the same time point, the average BBB scores of the treadmill and the combined groups were significantly higher. Compared with the ultrashort wave group, the average BBB score of the treadmill group was higher after 4 weeks, and the combined group′s average was significantly higher at 2, 3 and 4 weeks after the operation. Four weeks after the SCI modeling, the average AQP-4 IOD and GFAP IOD levels of the ultrashort wave group, the treadmill group and the combined group were lower than that of the control group, while the average AQP-4 and GFAP IOD levels of the combined group were significantly lower than those of the ultrashort wave group. Compared with the treadmill group, the combined group had a significantly lower average GFAP level. Conclusions Both treadmill training and ultrashort wave treatment promote motor function recovery after a spinal cord injury. The mechanism may be related to downregulation of AQP-4 and GFAP expression at the injured site. Combining the two treatments gives better effects. Key words: Spinal cord injury; Treadmill training; Ultrashort wave irradiation; Auaporin protein-4; Glial fibrillary acidic protein

Facile and expedient synthesis of α,β-unsaturated isoxazol-5(4H)-ones under mild conditions

It was found that nano-SiO2–H2SO4 was catalyzed by the three-component cyclocondensation of aryl/heteroaryl aldehydes, hydroxylamine hydrochloride, and β-ketoesters toward the synthesis of α,β-unsaturated isoxazol-5(4H)-ones under green conditions. The reaction yielded the corresponding heterocycles at room temperature in relatively shorter reaction times. It merits mentioning that the mild conditions allow the synthesis of several α,β-unsaturated isoxazol-5(4H)-ones using this method. In this study, some new derivatives of isoxazolones were also synthesized and characterized. It is efficient, clean, simple, safe, and ecologically friendly. This straightforward method is cost-effective and requires no preparation of reactants. The three-component annulation was performed without using energy sources, for example, heat, ultrasound wave, and microwave irradiation.

75P - Pulse mode irradiation regimen of PDT results in high progression free and overall survival in mice with model tumour

BackgroundPhotodynamic therapy (PDT) is one of actively developing modalities of cancer treatment. During PDT procedure systemically injected photosensitizer molecules are activated by laser irradiation in tumor location leading to generation of singlet oxygen which induces cytotoxic effect. In modern clinical practice PDT uses continuous wave irradiation. In such mode fast depletion of molecular (triplet) oxygen in tissue occurs leading to reduction of PDT efficiency. Previously we have shown that photodynamic treatment using pulse mode irradiation regimens could be more efficient in damaging tumor cells than standard PDT due to reoxygenation (Klimenko et. al., Photodiagnosis Photodyn Ther., 2016). In present study we have evaluated specially designed pulse mode PDT regimes on tumor model in vivo. MethodsPDT pulse mode irradiation regimens were designed using physics and mathematical modelling. BALB/c male mice were subcutaneous injected into right flanks with CT26 murine colon carcinoma cells. At day ten after inoculation mice were randomized into 3 groups with 10 animals in each (control group, PDT at continuous wave irradiation mode – CW group, PDT at pulse irradiation mode – PM group) and PDT was made. The RadachlorinⓇ photosensitizer and «Lahta-Milon» semiconductor laser (662nm) were used. After treatment the tumor size was estimated every two days. All experiments were performed in accordance with the animal ethics guidelines. ResultsWe have designed new pulse mode irradiation regimens of PDT. We have shown that antitumor efficiency of PDT at pulse irradiation mode is much better than one at standard continuous wave irradiation mode. Median survival after day of treatment was 14 days in control group, 16 days in CW group and 28 days in PM group. In PM group 5 animals had total regress of tumor and progression free survival till the end of experiment (100 days after treatment) compared with only 1 animal in CW group. Thus, we can suggest that overall survival should be much higher in PM group. ConclusionsWe have demonstrated that PDT using pulse mode irradiation regimens is much more effective that PDT using standard regimens and leads to higher progression free and overall survival in mice with CT26 colon carcinoma. Legal entity responsible for the studyThe authors. FundingHas not received any funding. DisclosureAll authors have declared no conflicts of interest.

Inducing Mild Traumatic Brain Injury in C. elegans via Cavitation-Free Surface Acoustic Wave-Driven Ultrasonic Irradiation

Mild traumatic brain injury is an all-too-common outcome from modern warfare and sport, and lacks a reproducible model for assessment of potential treatments and protection against it. Here we consider the use of surface acoustic wave (SAW) irradiation of C. elegans worms—without cavitation—as a potential, ethically reasonable animal-on-a-chip model for inducing traumatic brain injury in an animal, producing significant effects on memory and learning that could prove useful in a model that progress from youth to old age in but a few weeks. We show a significant effect by SAW on the ability of worms to learn post-exposure through associative learning chemotaxis. At higher SAW intensity, we find immediate, thorough, but temporary paralysis of the worms. We further explore the importance of homogeneous exposure of the worms to the SAW-driven ultrasound, an aspect poorly controlled in past efforts, if at all, and demonstrate the absence of cavitation through a change in fluids from a standard media for the worms to the exceedingly viscous polyvinyl alcohol. Likewise, we demonstrate that acoustic streaming, when present, is not directly responsible for paralysis nor learning disabilities induced in the worm, but is beneficial at low amplitudes to ensuring homogeneous ultrasound exposure.

Synergistic catalytic effect between ultrasound waves and pyrimidine-2,4-diamine-functionalized magnetic nanoparticles: Applied for synthesis of 1,4-dihydropyridine pharmaceutical derivatives.

A convenient strategy for synthesis of the various derivatives of 1,4-dihydropyridine (1,4-DHP), as one of the most important pharmaceutical compounds, is presented in this study. For this purpose, firstly, magnetic iron oxide nanoparticles (Fe3O4 NPs) were fabricated and suitably coated by silica network (SiO2) and trimethoxy vinylsilane (TMVS). Then, their surfaces were well functionalized with pyrimidine-2,4-diamine (PDA) as the main active sites for catalyzing the synthesis reactions. In this regard, the performance of three different methods including reflux, microwave (MW) and ultrasound wave (USW) irradiations have been comparatively monitored via studying various analyses on the fabricated nanocatalyst (Fe3O4/SiO2-PDA). Concisely, high efficiency of the USW irradiation (in an ultrasound cleaning bath with a frequency of 50 kHz and power of 250 W/L) has been well proven through the investigation of the main factors such as excellent surface-functionalization, core/shell structure conservation, particle uniformity, close size distribution of the particles, and great inhibition of the particle aggregation. Then, the effectiveness of the USW irradiation as a promising co-catalyst agent has been clearly demonstrated in the 1,4-DHP synthesis reactions. It has been concluded that the USW could provide more appropriate conditions for activation of the catalytic sites of Fe3O4/SiO2-PDA NPs. However, high reaction yields (89%) have been obtained in the short reaction times (10 min) due to the substantial synergistic effect between the presented nanocatalyst and USW.

Synthesis and Characterization of Rise Husk Nanopores Carbon Through Ultrasonic Irradiation With H3PO4 Activators as Electrochemical Energy Storage Materials

The research on synthesis and characterization of carbon nanopores rice husk through ultrasonic irradiation by activators H3PO4 as electrochemical energy storage material has been made. This activated carbon is a basic material in making electrodes which will be developed into electrochemical energy storage material. Nanopores carbon is made from rice husks, which passes through three stages of the process and the development methods of manufacturing of previous activated carbon. Carbonization carried out at a temperature of 350 oC, then add the HF with the aim to remove silica from the carbon in order to increase its surface area, and chemical activation with H3PO4. Furthermore, the modified carbon through ultrasonic irradiation. Characterization of the surface of activated carbon is done through the analysis of XRD and XRF, characterization of functional groups by FTIR, surface area determination by the method of methylene blue, as well as the specific capacitance measurement with CV. The results showed the addition HF can remove carbon silica in rice husks. The element largest of the active carbon with ultrasonic wave irradiation is Ca or oxide CaO by 46,43 %, which has a crystallinity of phase with relatively mesoporous carbon pores. The surface area of activated carbon rice husk with irradiation of ultrasonic waves in optimum condition at a temperature of 30 ° C for 60 minutes which is 184.348426 m2 / g. The value of the specific capacity of the activated carbon energy storage rice husks with and without irradiation of ultrasonic waves each is 1067,75 nF/g and 622,17 nF/gram.

Laser patterning and growth mechanism of orientation designed crystals in oxide glasses: A review

There has been a great progress in the spatially selected patterning of crystals with a single crystal-like architecture by continuous wave (CW) and femtosecond (fs) pulsed laser irradiations in oxide glasses. Highly oriented crystals with different morphologies such as straight/bending/spiral lines and two-dimensional planar shapes are patterned using heat-driven type CW laser irradiations with a scanning mode. The features of the laser patterning of nonlinear optical crystals with birefringence such as β-BaB2O4, LaBGeO5, LiNbO3, and BaAlBO3F2 are focused, and the origin and mechanism of the c-axis orientation along the laser scanning direction are discussed from the viewpoints of surface energy and interfacial free energy between crystal and surrounding glassy phase. The homo-epitaxial crystal growth in the laser patterning of crystal lines and the rotation of crystal axes in ferroelastic β′-Gd2(MoO4)3 are demonstrated as unique features of the laser-induced crystallization. The laser-induced crystallization provides a new insight and more deep understanding for the nucleation and crystal growth in glasses and proposes a new crystal growth science and engineering in solid-state materials.

754 Near-infrared light 790-1000 nm causes photoaging in vivo and in vitro

Objective: Near-infrared radiation (NIR), which is a composition of sunlight with a 700-2000 nm wavelength, is associated with skin aging such as wrinkles and slacks. On the other hand, NIR irradiation is effective for the improvement of skin photo damage. In the present study, we examined the effect of NIR on the skin in vivo and in vitro using a NIR irradiation apparatus that controls wave length and irradiation dose. Methods: The NIR irradiation apparatus has a halogen flash lamp where the light is white similar to sunlight (790-1700 nm). The skin of hamsters or mice was irradiated every other day for 1.75-7 min with NIR (190 mW/cm2). After fixing skin tissues at 1, 3, and 5 days post-irradiation, hematoxylin-eosin and immunohistochemical staining and the measurement of intracutaneous temperature were performed. The expression of reactive oxygen species (ROS) and inflammatory cytokines was analyzed in NIR-irradiated human epidermal keratinocytes (HEK). Results: NIR irradiation with 780-1700 nm caused epidermal thickness, sebaceous hyperplasia, and the augmentation of matrix metalloproteinase 1 (MMP-1) expression in the auricle skin of the hamsters. In addition, the intracutaneous temperature was increased up to 47 oC. Furthermore, the increase of ROS and TNF-α production was detectable in the NIR-irradiated HEK. However, neither said histological alteration nor the increase of MMP-1, intracutaneous temperature, ROS, and TNF-α was detectable in a filter-selected NIR (>1000 nm) irradiated skin and HEK. Conclusion: These results provide novel evidence that NIR with 790-1000 nm wavelength causes photoaging actions such as epidermal thickness, sebaceous hyperplasia, and the augmentation of MMP and TNF-α production in epidermis in vivo, which are closely associated with an increase in intracutaneous temperature and ROS levels.

Breast cancer diagnosis with a microwave thermoacoustic imaging technique-a numerical approach.

Microwave-induced thermoacoustic imaging (MITAI) is an imaging technique with great potential for detecting breast cancer at early stages. Thermoacoustic imaging (TAI) combines the advantages of both microwave and ultrasound imaging techniques. In the current study, a three-dimensional novel numerical simulation of TAI phenomenon as a multi-physics problem is investigated. In the computational domain, a biological breast tissue including three different tissue types along with a tumor is placed in a tank containing castor oil and is irradiated by a 2.45-GHz pulsed microwave source from a rectangular waveguide. The generated heat in the biological tissue due to the electromagnetic wave irradiation and its corresponding pressure gradient in the tissue because of the temperature variations are evaluated. Also, capability of the MITAI process with respect to the tumor location and size is investigated. To identify the required power level needed for producing thermoacoustic signals, different power levels of microwave sources are investigated. The study's results demonstrate a minuscule increase in temperature as a result of the absorption of pulsed microwave energy (for example, a maximum of 0.002472°C temperature increase in tumor with 1cm diameter which is located in fatty tissue of breast are obtained due to an excitation pulse of 1000W, 1ms). This small temperature variation in the tumor produces several kilopascals of pressure variations with maximum of 0.584016kPa in tumor. This pressure variation will produce acoustic signals, which can be detected with an array of transducers and be used for image construction. Results demonstrate that the location of tumor in breast plays a vital role on the detecting performance of MITAI. Also, it is shown that very small tumors (with the diameter of 0.5cm) can also be detected using MITAI technique. These simulations and procedures can be used for determining the amount of produced pressure variation, the acoustic pressure magnitude, and other complicated geometries. Graphical abstract A schematic of the thermoacoustic phenomenon.

Millimeter wave exposure induces apoptosis in human melanoma A375 cells in vitro

To investigate the effects of millimeter wave (MMW) exposure on apoptosis of human melanoma A375 cells and explore the mechanisms. Through electromagnetic field calculation we simulated MMW exposure in cells and calculated the specific absorption rate (SAR). The optimal irradiation parameters were determined according to the uniformity and intensity of the SAR. A375 cells were then exposed to MMV for 15, 30, 60, or 90 min, with or without pretreatment with the caspase-3 inhibitor AC-DEVD-fmk (10 μmol/L) for 1 h at 90 min before the exposure. CCK-8 assay was used to assess the changes in the viability and Annexin-V/ PI staining was used to detect the apoptosis of the cells following the exposures; Western blotting was used to detect the expression of caspase-3 in the cells. The results of electromagnetic field calculation showed that for optimal MMV exposure, the incident field needed to be perpendicular to the bottom of the plastic Petri dish with the antenna placed below the dish. CCk-8 assay showed that MMW exposure significantly inhibited the cell viability in a time-dependent manner (P < 0.05); exposures for 15, 30, 60, and 90 min all resulted in significantly increased apoptosis of the cells (P < 0.05). The cells with MMW exposure showed significantly increased expression of caspase-3. The inhibitory effect of MMW on the cell viability was antagonized significantly by pretreatment of the cells with AC-DEVD-fmk (P < 0.05), which increased the cell viability rate from (36.7±0.09)% to (59.8±0.06)% (P < 0.05). 35.2 GHz millimeter wave irradiation induces apoptosis in A375 cells by activating the caspase-3 protein.

A novel two-layer honeycomb sandwich structure absorber with high-performance microwave absorption

A novel method for fabricating the two-layer honeycomb sandwich structure absorber (THSSA) was developed. The honeycomb cores with different pore sizes coated with epoxy resin filled with conductive carbon black as lossy filler have been fabricated by dipping processes. The microwave absorption properties of the honeycomb sandwich structure absorber (HSSA) with one-layer honeycomb core and two-layer honeycomb core have been designed and measured using arch measurement system within 2–18 GHz. The matching layer on the top of the honeycomb core can enhance the microwave absorption properties. The value of reflection loss can reach −10 dB in the frequency range of 4.9–18 GHz with an absorber thickness 9 mm for the fabricated THSSA with the flaky carbonyl iron powder (FCIP)/epoxy resin composite at the bottom. It was shown that the THSSA with lightweight and broadband absorption properties have a promising future in decreasing electromagnetic wave irradiation and interference.

Structural reconfigurations of nanosheet arrays in layered minerals caused by wave irradiation: desorption mechanism of Cs from nanosheet edges.

In layered minerals typically available in soil, there exists a high concentration of nanosheet edge sites formed by overlap among two-dimensional (2D) nanosheets, which act as heavily adhesive Cs chemisorption sites. Here, we propose the application of irradiation with ultrasonic waves in addition to microwaves employing ethylenediaminetetraacetic acid (EDTA) chelate to aid the decontamination of Cs from the nanosheet edges. The energy deposition by irradiation with both micro and ultrasonic waves is found to separate the overlap among the 2D nanosheets, succeeding in the desorption of Cs from the nanosheet edges. The decontamination of Cs became more prominent with ultrasonic irradiation owing to more efficient energy deposition than that with microwaves. The desorption mechanism is highlighted based on the results of systematic studies of the local structural reconfigurations of nanosheet arrays caused by wave irradiation. Surprisingly, not the aqueous solution nor interlayer water but constitution water triggers Cs desorption from the nanosheet edges, thus opening up a future decontamination strategy with a water saving system.

Synthesis of nitrogen-doped graphene wrapped SnO2 hollow spheres as high-performance microwave absorbers.

Nitrogen-doped graphene (NG)/SnO2 hollow sphere hybrids were synthesized in this work. The chemical composition, crystal structure and morphology have been characterized by FT-IR spectra, XRD, Raman spectra, XPS, SEM and TEM in detail. Reflection loss (RL) values of NG/SnO2 hollow sphere hybrids less than −10 dB and −20 dB are found in the wide frequency range of 4.5–18 GHz and 5–16.2 GHz within 1.3–3.5 mm, and a minimum RL of −50.3 dB is achieved at 8.6 GHz with the matching thickness of only 2.3 mm. The results indicate that the NG/SnO2 hollow sphere hybrids with high-performance microwave absorption properties have a promising future in decreasing electromagnetic wave irradiation and interference.

Ultrasonic Studies of Solid Azobenzene-Decorated Polymer Thin Films.

This work investigates the effect of ultrasound on switching of cis azobenzene isomers to their trans counterparts in solid films of methyl methacrylate and methacryloyloxyazobenzene copolymers [P(MMA/MOAB)]. Ultraviolet–visible and 1H nuclear magnetic resonance spectroscopies demonstrate that 46% of the cis isomer converts to the trans form purely by ultrasonic agitation and 46% converts to the trans isomer by localized ultrasound-induced heating effects. Comparative studies of isomerization by ultrasound wave, heat, and visible irradiation show that ultrasound exposure requires a longer time to switch the cis-to-trans conformation. The estimated activation energy for the cis-to-trans conversion in solid polymer films is shown to be comparable to previous values of azobenzene isomerization, indicating that incorporation of the chromophore in a polymeric system affects the kinetics of transition but not the barriers to conformational change.

AN EFFICIENT VOLUME REDUCTION APPROACH FOR WATER DREDGED SOIL BY ULTRASONIC WAVE

Dredged soil caused by dredging work has brought the limits of the capacity of sediment disposal facilities in Japan. One way to solve this problem is considered to efficiently reduce the dredged soil and secure the capacity of the sediment disposal facilities. As a method of volume reduction, the technique utilizing ultrasonic vibration for compacting of soil particles has been studied so far. There are two purposes of this study. One is to clarify the volume reduction characteristic of water dredged soil by ultrasonic wave irradiation by changing the frequency or output voltage. The other is to take aim at 30% of the volume reduction. In the experimental method, the slurry of either sand or silt, its moisture content adjusted to 150%, was poured into each container. Ultrasonic wave was irradiated from the horizontal direction. After the experiment, the mass of the sample was measured. Relative density and volume reduction ratio were calculated through wet density, dry density, and void ratio. As a result, the highest volume reduction ratio of 27% was obtained when the ultrasonic wave of frequency 28kHz with output voltage 200V were irradiated in the silt. In conclusion, although we did not reach the target volume reduction of 30%, we were able to confirm the increase in density and the decrease in volume.