This study evaluated the impact of climate change and water allocation scenarios on water security in the Seomjin River Basin using K-WEAP (Korea-Water Evaluation and Planning System). The findings indicated that domestic water and instream flow are vulnerable to climate change, while industrial water supply may fail to meet future demand in certain regions. Moreover, prioritizing instream flow was found to compromise the stability of the domestic water, and equal allocation adversely affected both domestic and industrial water security. Consequently, maintaining the current system appears to be the most effective approach; however, future studies should focus on developing flexible strategies that consider the effects of climate change and regional characteristics in a more detailed manner.