In recent decades, extreme climatic events have been a major issue worldwide. Regional assessments on various climates and geographic regions are needed for understanding uncertainties in extreme events' responses to global warming. The objective of this study was to assess the annual and decadal trends in 12 extreme temperature and 10 extreme precipitation indices in terms of intensity, frequency, and duration over the Loess Plateau during 1960–2013. The results indicated that the regionally averaged trends in temperature extremes were consistent with global warming. The occurrence of warm extremes, including summer days (SU), tropical nights (TR), warm days (TX90), and nights (TN90) and a warm spell duration indicator (WSDI), increased by 2.76 (P<0.01), 1.24 (P<0.01), 2.60 (P=0.0003), 3.41 (P<0.01), and 0.68 (P=0.0041) days/decade during the period of 1960–2013, particularly, sharp increases in these indices occurred in 1985–2000. Over the same period, the occurrence of cold extremes, including frost days (FD), ice days (ID), cold days (TX10) and nights (TN10), and a cold spell duration indicator (CSDI) exhibited decreases of −3.22 (P<0.01), −2.21 (P=0.0028), −2.71 (P=0.0028), −4.31 (P<0.01), and −0.69 (P=0.0951) days/decade, respectively. Moreover, extreme warm events in most regions tended to increase while cold indices tended to decrease in the Loess Plateau, but the trend magnitudes of cold extremes were greater than those of warm extremes. The growing season (GSL) in the Loess Plateau was lengthened at a rate of 3.16days/decade (P<0.01). Diurnal temperature range (DTR) declined at a rate of −0.06°C /decade (P=0.0931). Regarding the precipitation indices, the annual total precipitation (PRCPTOT) showed no obvious trends (P=0.7828). The regionally averaged daily rainfall intensity (SDII) exhibited significant decreases (−0.14mm/day/decade, P=0.0158), whereas consecutive dry days (CDD) significantly increased (1.96days/decade, P=0.0001) during 1960–2013. Most of stations with significant changes in SDII and CDD occurred in central and southeastern Loess Plateau. However, the changes in days of erosive rainfall, heavy rain, rainstorm, maximum 5-day precipitation, and very-wet-day and extremely wet-day precipitation were not significant. Large-scale atmospheric circulation indices, such as the Western Pacific Subtropical High Intensity Index (WPSHII) and Arctic Oscillation (AO), strongly influences warm/cold extremes and contributes significantly to climate changes in the Loess Plateau. The enhanced geopotential height over the Eurasian continent and increase in water vapor divergence in the rainy season have contributed to the changes of the rapid warming and consecutive drying in the Loess Plateau.