Objective: To evaluate 3D nasolabial morphology, relative to contemporaneous non-cleft data, following primary reconstruction of unilateral cleft lip and palate (UCLP). Materials and methods: Prospective, cross-sectional, case-control study performed on two groups of children, 21 with surgically repaired UCLP and 73 controls were examined at 3 years using stereophotogrammetry. 3D co-ordinates of anthropometric landmarks were extracted from virtual reality modelling language images created by computerized stereophotogrammetry. To assess the reproducibility of landmarks digitization, a randomly selected 20 3D models were redigitized. Systematic and random errors were calculated according to Dahlbergh equation. Results: Landmarks digitization error was within 0.5 mm. Nasolabial appearance was improved following cleft repair but was significantly different from non-cleft children at the following areas: (1) asymmetry of the nose with display of the alar base on the affected side more laterally and inferiorly; (2) midface hypoplasia; (3) short upper lip on the cleft side; (4) asymmetry of the nostrils There was no statistical significant difference in columella width between the UCLP group and control group. Conclusions: 3D imaging is an emerging modality that is suitable for paediatric population. Geometric morphometrics is superior to traditional analysis of facial morphology. The soft tissue facial deformity in 3-year-old children with unilateral cleft lip and palate is closely related to the site of primary surgery.
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