The present paper aims to determine possible approaches to the analysis of side electromagnetic radiation (EMR) of the monitor video subsystem with the DisplayPort interface within the framework of the investigation of computer processed information (CPI) security. An automated workplace with a single monitor and, accordingly, a specification for a single-threaded video signal transmission mode is considered as the CPI under study. In order to achieve this aim, the components of the DisplayPort interface architecture, the characteristics of the signal propagation medium from the source to the receiver and algorithm for forming transport units have been studied. The correlation between the number of active data transmission lines, the clock frequency per line and the characteristics of the transmitted data are described. The conducted experiment has shown that the power of the EMR depends on the shielding actions used in the cable design. When studying the interface architecture components that affect the EMR energy spectrum, it was found that the interference immunity of the main channel lines depends on the settings of the DisplayPort - DPCD. This dependence makes possible to change the configuration (for example, scrambling, data encryption and the use of frequency modulation with an extended spectrum) by software tools and thus significantly affect the quality of laboratory testing. Based on the results of the present study, a procedure for analyzing the necessary information for the application of approaches is proposed and the procedure for applying instrumental actions in preparation for laboratory studies is developed. This will allow obtaining more accurate values of the power of the useful signal when monitoring the processed information security of the CPI with the DisplayPort interface. Further research will be aimed at laboratory tests of the described approaches under operating conditions.