Explosion always happens in turbulent field, which is hard to measure in reality. This paper explores the influence of turbulent kinetic energy on the propagation behaviors of flame and pressure of stoichiometric hydrogen-air explosion in confined vessel, using large eddy simulation. The momentum equation and progressive variable equation are adapted to consider interaction of turbulence and flame. The results reveal that with initial turbulent kinetic energy increasing, its promoting effects on flame and pressure propagation weaken. For flame at low initial turbulent kinetic energy and low initial pressure, it undergoes three propagating stages: acceleration, steady propagation and deceleration. In addition, flame deceleration is caused by rapid decrease of flow velocity which falls faster with initial turbulent kinetic energy increasing. Furthermore, explosion pressure propagates faster with initial turbulent kinetic energy increasing. Sharp fluctuation of flow velocity appears in the flame zone where big pressure gradient exists.