The purpose of article is to study the availability of historiographical and source studies opportunities for didactic use of the topic of the pre-scientific period of chemistry, bearing in mind both the natural sciences and the humanities. The methodological basis was the study of historiography and the source base of the topic, especially the alchemical period of development of chemical knowledge. Conclusions. The availability of the material in the pre-scientific period of development of chemistry as a research spere, didactic significance in both scientific and chemical and humanitarian aspects allows the creation of a study subject for medical students. This study subject brings students to understanding, how to develop theoretical and practical knowledge in the field of chemist research and its impact on medical science in the historical aspect. It will ensure the acquisition of the main essence from the stages of formation of chemistry as a science and dialectic of its development, the continuous connection with the manufacture of drugs. Students of the course will learn the evolution and patterns of development of chemical knowledge. In addition, the study subject should contribute to the understanding of the humanitarian component of the alchemical stage in the development of chemistry and philosophy, anthropology and culture.