Aim. To study clinical and epidemiological data in males and females with ureaplasma infection and to evaluate efficacy of magneto-laser therapy used as additional treatment of ureaplasma infection.
 Methods. 104 patients (94 men and 10 women) with urogenital ureaplasma infection were observed. Patients were divided into two groups: a study group (n=55) that received standard and magneto-laser therapy, and a comparison group (n=49) that received only standard treatment. Polymerase chain reaction was used to investigate samples for Mycoplasma hominis, Ureaplasma parvum and urealyticum, and bacteriological study for Mycoplasma hominis and Ureaplasma spp. was additionally performed with determining their antibiotic susceptibility. Magnetic therapy was conducted with the use of Michelangelo device (Italy) for 10 minutes to small pelvis area for 10 days.
 Results. As a result, 78 (82.9%) males were diagnosed with uretritis, 52 (55.3%) with prostatitis, 37 (39.3%) with cystitis. In females monoinfection was more prevalent than in males (50.0% vs 40.4%). Ureaplasmosis predominantly affected subjects aged 20-29 (97.8%) and 30-39 (86.0%) years. In female group, patients aged 20-29 years prevailed, while in a male group - patients aged 30-39 years. In males, the association of Ureaplasma with Mycoplasma hominis (36.1%) prevailed.
 Conclusion. Complex treatment of ureaplasma infection of urogenital tract including magneto-laser therapy demonstrated high clinical efficacy and allowed achieving clinical and laboratory cure of ureaplasma infection in 85.4% of cases.