Ultrasonic Power Density Research Articles

Energy consumption evaluation of liquid food ultrasonic evaporation process

Abstract Ultrasonic evaporator is a new type of evaporation equipment using ultrasonic technology to assist evaporation and concentration. It is especially suitable for the materials which are easy to scale and foam. Due to the complexity of heat and mass transfer during ultrasonic technology to assist liquid evaporation process, there are few reports on the energy consumption of ultrasonic evaporation. In this paper, the effects of ultrasonic density, evaporation temperature, and feed flow rate on the total energy consumption of ultrasonic evaporation were studied and tap water was selected as experimental material. It was found that the optimal condition for this ultrasonic evaporator were the ultrasonic power density of 4 × 10−5 W/m2, the evaporation temperature of 65 °C, and the feed rate of 1.389 × 10−5 m3/s. According to the orthogonal test and analysis of variance, it can be obtained that the influence of evaporation temperature on total energy consumption is the largest, the second is feed flow rate, and ultrasonic power density has the least influence.

Effect of solvent composition and its interaction with ultrasonic energy on the ultrasound-assisted extraction of phenolic compounds from Mango peels (Mangifera indica L.)

Ultrasound has been used to intensify the extraction of phenolic compounds from many agro-food products. However, there is still a lack of understanding on how the ultrasonic energy is influenced by blends of different solvents and how this impacts the extraction process. This work studied the effect of ethanol, acetone and hexane blends on the ultrasonic power density (UPD) generated during the extraction of phenolic compounds from Mango peel, using an ultrasonic-assisted extraction (UAE) and a conventional solvent extraction (CSE). A simplex centroid mixture design and a special cubic regression model were used to evaluate the total phenolic compounds (TPC), antioxidant activity (AA) and ultrasonic intensity (UI) as a function of the solvents proportions. The greatest TPC was obtained with the ethanol–acetone blend (60–40%) for CSE (205.08mg GAE/100g DM) and UAE (1493.01mg GAE/100g DM). Likewise, an increase (avg. 630%) was observed in TPC when the ultrasound was applied for all solvents and their blends. The TPC showed a good correlation (r=0.81) with the UPD, with higher UPD resulting in larger amounts of TPC extracted. Nevertheless, for the ethanol–acetone blend there was a decrease of 14.2% of the AA for the UAE, which could be due to the sonochemical reactions taking place at the high UPD achieved for that blend. The results of this work indicate that the solvent composition and use of ultrasound should be carefully selected to achieve the desired extraction objectives.

Protein extraction and sludge dewatering performance of ultrasound-assisted enzymatic hydrolysis of excess sludge.

Excess sludge contains a high amount of protein, which can be recovered to prepare protein foaming agents and other products with high added value. Enzymatic hydrolysis (EH) is a promising technology for the recovery of protein from excess sludge, and ultrasound has been identified as a potential method to assist in sludge disintegration. Ultrasonic pretreatment was combined with alkaline protease hydrolysis to extract protein from excess sludge produced by A2/O treatment (S1) and an oxidation ditch treatment (S2), and the extraction effects and changes in sludge dewatering performance were studied. The effects of the six factors ultrasonic power density, ultrasonication time, enzyme dose, pH, hydrolysis temperature and hydrolysis time were analyzed. The results showed that the ultrasound-enhanced enzymatic method could effectively extract sludge protein. Although the extraction efficiencies for the different municipal sludges were different, their extraction conditions were relatively similar. Considering the protein extraction rate and sludge dewatering performance, the selected extraction conditions were as follows: ultrasonic power density, 1W/mL; ultrasonication time, 20min; enzyme dose, 3500U/g; pH11; hydrolysis temperature, 60°C; and hydrolysis time, 3h. Under these conditions, the protein extraction rate (Rp) of S1 and S2 reached 55.9% and 52.3%, respectively. Moreover, the improvement in sludge dewatering performance (Dw) of S1 and S2 was 49.5% and 52.4%, respectively. Comparison of the protein, polypeptide, and amino acid contents obtained from ultrasound-assisted enzymatic hydrolysis (UEH), EH, and ultrasonic hydrolysis (UH) further demonstrated the beneficial effect of ultrasound application on enzymatic hydrolysis.

Improvement in enzymolysis efficiency and changes in conformational attributes of corn gluten meal by dual-frequency slit ultrasonication action.

The influences of dual-frequency slit ultrasound (DFSU) pretreatment with various working parameters on the enzymolysis efficiency and conformational characteristics of corn gluten meal (CGM) were studied. Results indicated that under the conditions of ultrasonic power density of 80W/L, time of 30min, ultrasonic intermittent ratio of 5:2s/s, temperature of 30°C, and substrate concentration of 50g/L, the relative enzymolysis efficiency (REE) of CGM reached a maximum of 21.05%, and the protein dissolution rate was 68.50%. In addition, ultrasonication had considerable impact on the conformation of CGM and consequently improved the susceptibility to alcalase proteolysis. Changes in free sulfhydryl (SHF) and disulfide bonds (SS) groups indicated spatial conformation of CGM was altered following sonication (sonochemical) treatment. Fourier Transform Infrared Spectrum (FITR) analysis showed a reduction in α-helix and β-turn content; and an increase in β-sheet and random coil content of CGM. Alterations in the particle size, particle size distribution, microstructure and surface roughness (Ra, Rq) indicated generation of smaller and more uniform protein fragments of CGM by sonochemical pretreatment. The proposed mechanism of sonicated CGM was elaborated. Our findings suggest that using DFSU in pretreating CGM may be an efficacious approach to enhance proteolysis.

Quantitative analysis and kinetic modeling of ultrasound-assisted exfoliation and breakage process of graphite oxide

Ultrasonic exfoliation is the most widely used delamination technique for producing graphene oxide. In this work, the exfoliation of graphite oxide suspension is conveniently monitored via real-time measurement of viscosity and then quantitatively described by using the relative single-layer fraction (α) for the first time, by which the full exfoliation is achieved with a time scale of minutes. Lateral size evolution is demonstrated using lognormal distribution based on statistical analysis. With the quantization of relative single-layer fraction and lateral size distribution, a prototype database has been built to efficiently integrate experimental data tested under different process conditions (suspension concentration, ultrasonic frequency, and ultrasonic power density), which can be used as reference guides for process optimization and product control. The selection and breakage functions (Si and Bij) of ultrasound-assisted exfoliation are calculated and the breakage mechanisms of graphite oxide are found attributed mainly to sheet fracture.

Green ultrasound-assisted extraction of chlorogenic acids from sweet potato peels and sonochemical hydrolysis of caffeoylquinic acids derivatives.

Sweet potato peels are rich in chlorogenic acids. In this work, we applied ultrasound technology to extract the main compounds from sweet potato peel and used multivariate analysis and principal component analysis (PCA) to evaluate the effects of different extraction conditions on the extraction of chlorogenic acids. The extraction was studied varying ultrasonic power density (20, 35 and 50W/L) and processing time (5, 10, 20 and 40min) using an ultrasonic bath operating at 25kHz. The chemical analysis was carried out by UPLC-qTOF-MS, and the results were evaluated by PCA and PLS-DA chemometric analysis. Results show that both ultrasonic power density and processing time influences in the extraction of different chlorogenic acid, and that different extraction conditions can be used to selectively extract specific caffeoylquinic acids and feruloylquinic acids in higher amounts. Ultrasound promoted the hydrolysis of tricaffeoylquinic acid when subjected to ultrasonic waves (20-50W/L), and of 3,4-caffeyolquinic acid at high ultrasonic power density (50W/L).

Ultrasonic modification of pectin for enhanced 2-furfurylthiol encapsulation: process optimization and mechanisms.

Pectin is an intriguing polymer, which is usually regarded as a byproduct from agricultural and biological processes. In previous studies, ultrasound treatment has been explored to improve the functionality of pectin but most of that work focused on aspects of molecular structure and the chemical properties of pectin. In this study, we utilized ultrasound treatment to modify the physiochemical properties of pectin. Using ultrasound treatment, we evaluated the emulsifying capability of pectin as a function of ultrasonic time and power density, using a response surface approach. A very potent yet unstable coffee-like aroma compound, 2-furfurylthiol, was also used for comparing the encapsulation feasibility of emulsion made with original pectin and ultrasound-treated pectin. Our results showed that the particle size of pectin was highly correlated with power density and ultrasound time. Approximately 370 nm of pectin particle size could be reached at a power density of 1.06 W mL-1 for 40 min. Ultrasound treatment increased emulsion droplet size but significantly improved emulsifying capacities, such as centrifugal stability and surface loading, although it was highly dependent upon the ultrasound treatment condition. When used as the encapsulation wall material, the ultrasound-modified pectin had significantly enhanced performance compared with the original, in terms of flavor retention over time at 45 °C and 65 °C. Ultrasound treatment was able to modify the physiochemical properties of pectin, which thus improved emulsification stability and encapsulation feasibility by forming a thicker layer at the oil / water interface to protect the core materials. © 2019 Society of Chemical Industry.

Comparison and optimization of extraction protocol for intracellular phosphorus and its polyphosphate in enhanced biological phosphorus removal (EBPR) sludge

Intracellular polyphosphate (poly-P) plays important roles in Enhanced biological phosphorus removal (EBPR) process, but an effective and reliable protocol for extracting intracellular P and its poly-P in EBPR sludge without hydrolysis of poly-P has not been setup yet. In the study, it was revealed that the severe hydrolysis of intracellular poly-P occurred during the different extraction processes, such as acid (i.e., HClO4, H2SO4 and HCl), basic (i.e., NaOH and KOH) and freezing-grind (under different solid-liquid ratios), but it did not occur during ultrasonic extraction process. The optimal extraction process of the ultrasonic protocol was 10 w/mL of ultrasonic power density and 15 min of ultrasonic time, when the extraction efficiency of intracellular P was 88.24 ± 1.56%. In addition, the extraction efficiency of intracellular P could be furtherly improved by that the 0.75 mol/L LiCl solution was used to resuspend the bacterial cell before ultrasonic extraction (i.e., LiCl-ultrasonic protocol). The ultrasonic protocol was more suitable to extract the intracellular P and its poly-P of EBPR sludge than the other 4 protocols (i.e., PCA-NaOH, EDTA-NaOH, freezing-grind and LiCl-ultrasonic), which had the technical characteristics of (i) with relatively high extraction efficiency of intracellular P, (ii) without hydrolysis of intracellular poly-P, (iii) with weak noise signal in 31P NMR spectrum and (iv) with simple extraction process and short extraction time. It was founded by the ultrasonic protocol that there was the high content (82.88%–89.79% of intracellular P content) of intracellular poly-P with long average chain length (376.4–383.2) in the EBPR sludges. Importantly, it was confirmed that the EBPR process was related to the combined action of extracellular and intracellular poly-P using a new fractionation method of P in EBPR sludge, which included the ultrasonic protocol at high power density for extracting the intracellular P and its poly-P.

Effects of ultrasonic treatment and current density on the properties of hydroxyapatite coating via electrodeposition and its in vitro biomineralization behavior.

In this study, ultrasonic-assisted electrodeposition is used to prepare uniform and smooth hydroxyapatite (HA) coating on the surface of the braids, which can be potentially applied as biodegradable bone scaffolds. During the electro-deposition process, the ultrasonic power (0 W and 20 W) and current density (2.5, 5.0, and 7.5 mA/cm2) are altered in order to evaluate their influences on the properties of HA coating over the braid surface. The field emission scanning electron microscope (FE-SEM) images show that the crystals growth stages of HA include spherical particles, plate-like and needle-like crystals when electro-deposited for 15, 30, 45, and 60 min. In particular, when electro-deposited for 60 min, the needle-like structure of HA coatings shows a significant increase in density as a result of increasing the current density or the employment of ultrasonic treatment. Transmission electron microscope (TEM) results show that when the current density increases from 2.5 mA/cm2 to 7.5 mA/cm2, the grain size decreases from 413.65 ± 63.12 nm to 264.56 ± 65.33 nm. With the aid of ultrasonic treatment, the HA coating demonstrates a calcium‑phosphorus (Ca/P) ratio that resembles that of the human skeleton being 1.67. The X-ray Diffraction (XRD) results show the highest crystallinity reaches 73.52% at 7.5 mA/cm2-20 W. The cavitation effect of ultrasonic can improve the roughness of HA coating distinctively. Finally, the 7-day immersion into simulated body fluid (SBF) demonstrated a denser and finer apatite precipitation on the HA coating fabricated by ultrasonic-assisted electrodeposition. Therefore, this study provides a feasible ultrasonic-assisted electrodeposition method that yields a good morphology of bioactive substances coating over braid or other rugged deposition substrate for potential degradable bone scaffolds.

Ultrasound Assisted Synthesis of Size-Controlled Aqueous Colloids for the Fabrication of Nanoporous Zirconia Membrane.

Permeation and separation efficiency of ceramic membranes are strongly dependent on their nanoporous structures, especially on the pore size. In this work, ultrasound is employed to form the size-controlled ZrO2 nanoparticles, and a ceramic membrane is prepared with tunable pore size. Under the ultrasound treatment, H+ from water plays a key role in the synthesis process. The cavitation caused by ultrasound promotes the hydrolysis of the precursor in water, which produces a large number of H+. These H+ will react with precipitant added and generate cyclic tetrameric units. Excess H+ can peptize cyclic tetrameric units and form an electrical double layer, resulting in a stable sol. Unlike ultrasound treatment, precipitant will react directly with the precursor and generate precipitation if there is no ultrasound added. Moreover, cavitation is good for the dispersion of cyclic tetrameric units. The particle size of Zr-based colloidal sol can be tuned in the ranges of 1.5 to 120 nm by altering the molar ratio of precursor to precipitant, ultrasonic power density and radiation time. Meanwhile, ultrasonic power density and radiation time have effects on grain size and the crystalline transition temperature of particles which influence performance of the ceramic membrane. As a result, membranes exhibit high performance together with high permeability and desirable rejection. To develop such a simple and controllable method for tuning particle size is extremely important in the preparation of nanoporous ceramic membranes.

Enhanced sonocatalytic degradation of carbamazepine and salicylic acid using a metal-organic framework

A metal-organic framework (MOF) was used as a sonocatalyst for ultrasonic (US) processes, to improve the degradation of two selected pharmaceutical active compounds (PhACs); carbamazepine (CBM) and salicylic acid (SA). The intrinsic characteristics of the MOF were characterized using a porosimeter (N2-BET) and scanning electron microscope (SEM). Various experiments were carried out under conditions with different US frequencies (28 and 1000 kHz), US power densities (45–180 W L−1), pH conditions (3.5, 7, and 10.5), and temperatures (293, 303, and 313 K) to investigate the degradation rates of the selected PhACs. Improved removal rates of PhACs were demonstrated within 60 min at 28 kHz (46% for SA; 47% for CBM) and 1000 kHz (60% for SA; 99% for CBM) with an MOF concentration of 45 mg L−1 in the US/MOF system, in comparison to 28 kHz (20% for SA; 25% for CBM) and 1000 kHz (37% for SA; 97% for CBM) under the ‘US only’ process. The removal of CBM was greater than that of SA under all experimental conditions due to the intrinsic properties of the PhACs. The degradation rates of PhACs are related to the quantity of H2O2; degradation is thus mostly affected by OH oxidation, which is generated by the dissociation of water molecules. The advantages of the ‘US/MOF system’ are as follows: (i) dispersion of MOF by US can improve sites and reactivity with respect to adsorption between the adsorbate (PhACs) and the adsorbent (MOF), and (ii) dispersed MOF acted as additional nuclei for water molecule pyrolysis, leading to the production of more OH. Therefore, based on the synergy indices, which were calculated using the removal rate constants [k1 (min−1)] of the pseudo-first order kinetic model, the ‘US/MOF system’ can potentially be used to treat organic pollutants (e.g., PhACs).

Removal of Microcystis aeruginosa by ultrasound: Inactivation mechanism and release of algal organic matter

The efficacy of ultrasonic irradiation for removal of Microcystis aeruginosa and release of algal organic matter (AOM) was investigated under different ultrasound conditions, including ultrasonic frequency, power density, and time. Laboratory results suggested that the ultrasonic efficiency and the release of AOM were influenced by frequency, power density, and time. The mechanism of AOM algae removal by ultrasound was systematically explored. The inactivation of algae resulted from mechanical and chemical effects caused by ultrasound. Mechanical destruction and free-radical oxidation considerably affected the structure and physiological function of algal cells. The SEM and TEM images indicated that ultrasound could damage the cell membrane, wall, and organelle. Flow cell cytometry results showed decreases in the size, internal granularity, integrity, and activity of algal cells, revealing that ultrasound exerted severe damage to the structure and function of algal cells. The activity of the antioxidant system of algal cells was then studied by investigating changes in MDA, SOD, and CAT concentration after ultrasound to confirm the inactivation of the cells. The release of AOM was explored by determining changes in water quality indices (UV254, DOC, and SUVA) at 10 min and 48 h after ultrasound. This study provides information about the safety of ultrasound usage on algae removal and references for ultrasonic parameters to be selected to ensure effective and safe algae removal.

Enhancement of Heat Transfer Performance Using Ultrasonic Evaporation

Abstract The ultrasonic evaporator is a new type of evaporation equipment which uses ultrasonic technology to assist evaporation of liquid materials. Due to the lack of mechanism of ultrasonic technology to enhance the heat transfer in evaporation process, there are few reports on the use of ultrasonic evaporator in industrial production. The tap water was selected as experimental material and the heat transfer performance of ultrasonic evaporator was studied. It could be obtained from the single factor analysis that the heat transfer coefficient increased first and then decreased with the increase of ultrasonic power density. The increase of heat transfer due to the increase of temperature difference is basically stable at 20 %. When the ultrasonic wave acts on evaporator, the heat transfer coefficient would increase about 17.06 %–29.85 %. According to the orthogonal test and analysis of variance, it can be obtained that the influence of temperature difference on heat transfer coefficient is the largest, the second is feed flow rate, and evaporation time has the least influence.

Effect of Ultrasonication on Self-Assembled Nanostructures Formed by Amphiphilic Positive-Charged Copolymers and Negative-Charged Drug

Self-assembly of the amphiphilic copolymer into core–shell-like nanoparticles is the new tactic to tailor carriers toward rationalization in the field of drug-delivery systems. Herein, a facile route for examining how the entrapment of a hydrophobic and negative-charge drug affects the micellar structure of a positive-charged copolymer and its biological behavior was developed. In this study, Pluronic F127-grafted chitosan (CF127) was utilized as a positive-charged copolymer for in situ loading of nanocurcumin in a cosolvent condition. Ultrasonication was found to be an effective method to control the self-assembly of phosphocasein and its interaction with curcumin. The superstructure of the incorporated nanoparticles was fabricated in the medium under unimolecular micelles as vesicular structure (SV) at lower ultrasonic condition while large complex micelles (multimicelle aggregates, LCMs) at higher ultrasonic power density. According to transmission electron microscopy, variable UV–visible spectrophotom...

Cavitation Technology—The Future of Greener Extraction Method: A Review on the Extraction of Natural Products and Process Intensification Mechanism and Perspectives

With growing consumer demand for natural products, greener extraction techniques are found to be potential alternatives especially for pharmaceutical, nutraceutical, and cosmetic manufacturing industries. Cavitation-based technology has drawn immense attention as a greener extraction method, following its rapid and effective extraction of numerous natural products compared to conventional techniques. The advantages of cavitation-based extraction (CE) are to eliminate the application of toxic solvents, reduction of extraction time and to achieve better extraction yield, as well as purity. The cavitational phenomena enhance the extraction efficiency via increased mass transfer rate between the substrate and solvent, following the cell wall rupture, due to the intense implosion of bubbles. This review includes a detailed overview of the ultrasound-assisted extraction (UAE), negative pressure cavitation (NPC) extraction, hydrodynamic cavitation extraction (HCE) and combined extractions techniques which have been implemented for the extraction of high-value-added compounds. A list of essential parameters necessary for the maximum possible extraction yield has been discussed. The optimization of parameters, such as ultrasonic power density, frequency, inlet pressure of HC, extraction temperature and the reactor configuration denote their significance for better efficiency. Furthermore, the advantages and drawbacks associated with extraction and future research directions have also been pointed out.

A reactor designed for the ultrasonic stimulation of enzymatic esterification

A laboratory scale ultrasonic flow reactor capable of enhancing enzymatic reactions has been built and characterized using as a model reaction the enzymatic synthesis of isoamyl acetate using Lipozyme 435 immobilized on a macroporous anion exchange resin. The efficiency of the reactor was determined in relation to ultrasonic power density (measured by 4-nitrophenol dosimetry), position of ultrasonic horn and temperature. The results show that ultrasound can enhance the process efficiency and also reduce the reaction time.

Thumba methyl ester production using prepared novel TiO2 nano-catalyst in ultrasonic cavitation reactor

In this present research, the catalytic activity of the prepared TiO2 nanoparticles was evaluated towards the thumba methyl ester production by using it under ultrasonic cavitation reactor. TiO2 nanoparticles were prepared by ultrasonic assisted sol-gel method using titanium tetra-isopropoxide (TTIP) as precursor. The required parameter like ultrasonic irradiation time was varied from 10 to 60 min, power density from 10 W/L- 30 W/L, initial temperature from 5°C -20°C and water to TTIP weight ratio from 5-20 for sol-gel method. After completing all the experimental activity, it was found that the morphology of TiO2 nanoparticles largely depends on the factors such as ultrasonic irradiation time, power density, inlet temperature and water to TTIP ratio. The prepared TiO2 nanoparticles were useful for the thumba methyl ester production up to 92% conversion of triglycerides from thumba oil in ultrasonic cavitation reactor.

Modeling and Bias-Robust Estimation of the Acoustic Release of Chemotherapeutics from Liposomes.

This paper models the acoustic drug release of chemotherapeutics from liposomes using a kinetic model that accounts for systematic biases affecting the drug delivery process. An optimal stochastic filter is then proposed to provide robust estimates of the percent drug released. Optimality is guaranteed by accurately identifying the underlying statistical noise characteristics in experimental data. The estimator also quantifies the bias in the release, exhibited by the experimental data. Drug release is experimentally measured as a change in fluorescence upon the application of ultrasound. First, a first-order kinetic model is proposed to model the release, which is aided by a bias term to account for the fact that full release is not achieved under the conditions explored in this study. The noise structure affecting the process dynamics and the measurement process is then identified in terms of the statistical covariance of the measured quantities. The identified covariance magnitudes are then utilized to estimate the dynamics of drug release as well as the bias term. The identified a priori knowledge is used to implement an optimal Kalman filter, which was initially tested in a simulation environment. The experimental datasets are then fed into the filter to estimate the state and identify the bias. Experiments span a number of ultrasonic power densities for liposomes. The results suggest that the proposed algorithm, the optimal Kalman filter, performs well in modeling acoustically activated drug release from liposomes.

A Review on Ultrasonic Catalytic Microbubbles Ozonation Processes: Properties, Hydroxyl Radicals Generation Pathway and Potential in Application

Ozone-based advanced oxidant processes (AOPs) have attracted remarkable attention as an alternative and effective approach for mineralization of refractory organics to innocuous substances. Key issues for ozone-based AOPs mainly focused on how to enhance ozone mass transfer and improve the production of hydroxyl radicals. Unfortunately, great efforts have been made, though, the application of ozone-based AOPs still remained in the laboratory scale due to lack of understanding of mechanisms of these hybrid processes. Besides, obtaining the balance of economical-technical feasibility is a great challenge. Ultrasonic catalytic microbubbles ozonation could be considered as a promising method, despite that there are a few studies that addressed this potential technology. Therefore, in this review, summaries about ozone-based microbubbles process, ultrasonic catalytic ozonation process, and ultrasonic catalytic microbubbles ozonation process have been provided in order to give a novel prospective about these hybrid technologies. The main influential parameters, such as initial pH, ozone dosage, intake flow rate, operating temperature, bubble size distributions, ultrasonic frequency, ultrasonic power density, and natural water constituents have also been well discussed. We truly hope that this paper will bring convenience to researchers that are devoted in the field of application of ozone-based AOPs for mineralizing refractory organics in wastewater.

Ultrasound as a pretreatment to reduce acrylamide formation in fried potatoes

Abstract Acrylamide is a compound that is potentially carcinogenic for human. This means that levels of acrylamide in foods should be reduced to a maximum. The acrylamide molecule is present in foods subjected to processes at temperatures above 120 °C, and it is formed through the reaction that takes place between asparagine and reducing sugars in the Maillard reaction. Fried potatoes are one of the main sources of acrylamide. In order to provide healthier food, this investigation proposes to apply high intensity ultrasound (US) as a frying pretreatment in water for 30 min, in order to reduce the acrylamide content of fried potatoes. Different US treatments were studied at distinct frequencies (35 and 130 kHz), ultrasonic power densities (0, 9.5, 47.6 and 95.2 W/kg), and water temperatures (30 and 42 °C). To evaluate the effects caused by ultrasonic cavitation, the increment of weight and moisture, the decrease in reducing sugars and the electrical conductivity of water in different treatments were evaluated. After frying, colorimetric analyses (L*, a* y b*) were carried out to ascertain the indirect formation of acrylamide in potatoes. At the temperature of 42 °C, the weight gain was greater as the ultrasonic power used in both frequencies was lower. Increments in US power densities decreased the potatoes' moisture gain and increased the electrical conductivity of soaking water. A treatment of 35 kHz and 92.5 W/kg at 42 °C provided an additional extraction of 31% of the reducing sugars over that of control samples. The colorimetric parameters L * and a * decreased and increased, respectively, with the frying time for the treatment at 35 kHz/92.5 W/kg/42 °C, which are a consequence of the reduction of reducing sugars by ultrasound. Thanks to the application of this treatment, 90% acrylamide content reduction was determined compared to potatoes fried directly, and up to 50% reduction with respect to control samples only soaked in water (42 °C/30 min). This investigation has demonstrated that US pretreatments can serve as a valid strategy to reduce the acrylamide content of fried potatoes.