Typical Error Research Articles

Retinopathy of prematurity in multiple births versus single births preterm, extremely preterm infants

The purpose of the study was to compare the retinopathy of prematurity in preterm, extremely preterm infants between multiple and single births.It was a hospital – based cross sectional comparative study conducted among preterm 28 - ≤37 weeks of gestational age, extremely preterm ≤ 28 weeks of gestational age at delivery of multiple and single births. Data on Gestational age, birth weight, birth order (single/multiple), Risk factors, Refractive status, and Treatment type were noted. Ophthalmological findings were performed routinely at 4 weeks and repeated later depending upon the severity. 49 infants were involved in this study; 22 were born as singletons and 27 as multiples. Our results show 2.0% of subject in stage 1, 18.4% in stage 2, 8.2% in stage 3, 2.0% in stage 4 substantially corresponds with the severity of retinopathy of prematurity due to lower gestational week and lower birth weight. Multiple birth infants statistically had 6.1% in stage 1, 18.4% in stage 2, 8.2% in stage 3, 2.0% in stage 4 retinopathy of prematurity than single birth infants. Risk factor results indicates necrotizing enterocolitis (33.3% in stage 2), oxygen (35.5% in stage 2 and 16.1% in stage 3), sepsis (37.9%, and 20.7% in stage 3), and continuous positive airway pressure (44.4% in stage 2 and 11.1% in stage 3) Compound hyperopic astigmatism was the most typical refractive error in both births. Laser treatment accounts for 18.1% in both groups. This study showed a significant correlation with ROP development in multiple births.

Stability of carboxy-hemoglobin during storage at different temperatures.

Accurate determination of carboxy-hemoglobin (COHb%) is essential for the assessment of hemoglobin mass (Hbmass) by CO-rebreathing. To analyze blood samples for a certain period of time after blood collection, it is necessary to know the stability of the COHb% during storage. The aim of the study was to determine the stability of COHb% at different storage temperatures over a period of up to 3months. Twenty-five milliliters of cubital venous blood was taken from five volunteers (three females and two males) before and after inhalation of 0.8/1.0mL/kg carbon monoxide and stored at +20°C and +4°C for 6days and at -70°C for 12 weeks. Within the first 6days, the blood was analyzed daily, then weekly for 12 weeks. Additionally, Hbmass was determined in 13 endurance athletes immediately after blood collection and after storage for 3days (eight cyclists) and 7days (five swimmers) at +20°C or +4°C. COHb% before and after CO inhalation was 1.56 ± 0.48 and 5.86 ± 1.12%, respectively, and remained unchanged over 6days, with no difference between storage at different temperatures. The standard deviation (STD) over time was between 0.07% and 0.12%. Similarly, storage at -70°C for 12 weeks did not change COHb%, whereas STD was 0.07%. Hbmass determined immediately and, after 3 or 7days of storage, differed by 10 ± 7 g and 15 ± 11 g corresponding to a typical error of 0.8% and 1.1%. Blood storage at +20°C and +4°C for 6days and at -70°C for 12 weeks does not affect COHb% and has, therefore, no influence on Hbmass assessment.

INSCYD physiological performance software is valid to determine the maximal lactate steady state in male and female cyclists.

The maximal lactate steady state (MLSS) is defined as the highest workload that can be maintained without blood lactate accumulation over time. The power output at MLSS (PMLSS) is regularly implemented to define training zones, quantify training progress, or predict race performance. The gold standard methodology for MLSS determination requires two to five trials of constant-load exercise, which limits the practical application in training. The INSCYD software can calculate the PMLSS (PMLSSINSCYD) based on physiological data that can be obtained during a ∼1 h laboratory visit. However, to the best of our knowledge, the validity of the most recent software version has not yet been investigated. This study aimed to assess the validity of the software's calculations on PMLSS in cycling. The data for this study were retrieved from two published scientific sources. Thirty-one cyclists (19 males, 12 females) performed a 15 s sprint to estimate the VLamax, a ramp test for the assessment, and two to five constant-load tests to determine the PMLSS. The INSCYD software was used to calculate the PMLSS based on the , VLamax, sex, body mass, and body composition. The PMLSSINSCYD was higher than the PMLSS in the entire sample (mean difference: 4.6 W, p < 0.05, 95% CI 0.8-8.3 W) and in men (mean difference: 6.6 W, p < 0.05, 95% CI 1.3-11.8 W), but not in women (mean difference: 0.8 W, n.s., 95% CI -3.7 to 5.3 W), which was within the typical error of the PMLSS estimations (∼3%). In 12 subjects (nine males, three females), the PMLSSINSCYD differed by 3.1-7.3% compared to the MLSS. The Pearson correlations between the measured PMLSS and the calculated PMLSS (PMLSSINSCYD) were very strong in men (r = 0.974, p < 0.001, 95% CI 0.933-0.99), women (r = 0.984, p < 0.001, 95% CI 0.931-0.996), and for the entire sample (r = 0.992, p < 0.001, 95% CI 0.982-0.996). In conclusion, the PMLSS can be accurately calculated using the INSCYD software, but it still requires advanced testing equipment to collect valid and VLamax data.

Reliability of enhanced paper grip test for testing foot strength in volleyball and soccer players

ObjectivesTo evaluate the reliability of the Enhanced Paper Grip Test (EPGT) for assessing foot strength in volleyball and soccer players. DesignA cross-sectional observational study with repeated measurements. SettingField-based study. ParticipantsA convenience sample of 28 athletes (13 volleyball players and 15 soccer players) participated in the study. Main outcome measuresThe main outcome measures were the intraclass correlation coefficients (ICC) for intra-visit and inter-visit reliability, typical error, and coefficient of variation for the force (N) recorded in EPGT test. ResultsThe EPGT demonstrated good to excellent relative reliability (ICC values ranged from 0.93 to 0.97) and acceptable absolute reliability (typical error = 5–8 % of the mean). Significant inter-limb asymmetries were observed in both volleyball (16.0 ± 10.2%) and soccer players (15.3 ± 9.8%). ConclusionsThe EPGT is a reliable tool for assessing foot strength in volleyball and soccer players. Further research is required to explore the applicability of EPGT in different athletic and clinical contexts, and its potential role in athletic performance and injury prevention.

OPTIMISING SPRINT PERFORMANCE: CONCURRENT VALIDITY AND RELIABILITY OF 25HZ GNSS UNITS FOR SPEED PROFILING

Sprint performance profiling is crucial for understanding an athlete’s capabilities and identifying potential areas for improvement. While traditional gold standard systems provide valid and reliable measurements, they are often costly, laboratory-based, or impractical for field-based settings. New GNSS units (25Hz) with higher sampling rates may address some of these limitations. The purpose of the project was to evaluate the concurrent validity and inter-unit reliability of 25Hz GNSS units by examining their agreement with laser devices for velocity measurements and timing gates for interval times. Validity was assessed during a track and field training session. 30 participants performed between 3 and 6 sprints over 40m whilst being assessed simultaneously through all systems. Inter-unit reliability was assessed on a closed athletics track by placing 3 GNSS units on a motor vehicle and completing 60 accelerations from 0-60m. Low mean bias (&amp;lt;1%) and typical error less than &amp;lt;2% for all measurements demonstrate excellent agreement between GNSS and criterion devices. The units demonstrated good reliability for the 0-10m interval (ICC = 0.86), excellent reliability for all remaining 10m intervals to 60m (ICC = 0.91-0.99), full times 0-60m (ICC = 0.97) and maximal sprint velocity (ICC = 1.0). These GNSS units offer a more efficient and practical alternative to traditional measurement devices. For coaches, this technology offers a scalable method to concurrently assess the sprint performances of multiple athletes during training and competitions, enabling evidence-based decisions to guide athletic development.

Identifying Pathological Myopia Associated Genes with A Random Walk-Based Method in Protein-Protein Interaction Network

Background: Pathological myopia, a severe variant of myopia, extends beyond the typical refractive error associated with nearsightedness. While the condition has a strong genetic component, the intricate mechanisms of inheritance remain elusive. Some genes have been associated with the development of pathological myopia, but their exact roles are not fully understood. Objective: This study aimed to identify novel genes associated with pathological myopia. Methods: Our study leveraged DisGeNET to identify 184 genes linked with high myopia and 39 genes related to degenerative myopia. To uncover additional pathological myopia-associated genes, we employed the random walk with restart algorithm to investigate the protein-protein interactions network. We used the previously identified 184 high myopia and 39 degenerative myopia genes as seed nodes. Results: Through subsequent screening tests, we discarded genes with weak associations, yielding 103 new genes for high myopia and 33 for degenerative myopia. Conclusion: We confirmed the association of certain genes, including six genes that were confirmed to be associated with both high and degenerative myopia. The newly discovered genes are helpful to uncover and understand the pathogenesis of myopia.

BIRD: Efficient Approximation of Bidirectional Hidden Personalized PageRank

In bipartite graph analysis, similarity measures play a pivotal role in various applications. Among existing metrics, the Bidirectional Hidden Personalized PageRank (BHPP) stands out for its superior query quality. However, the computational expense of BHPP remains a bottleneck. Existing approximation methods either demand significant matrix storage or incur prohibitive time costs. For example, current state-of-the-art methods require over 3 hours to process a single-source BHPP query on the real-world bipartite graph Orkut , which contains approximately 3 × 10 8 edges. We introduce BIRD, a novel algorithm designed for answering single-source BHPP queries on weighted bipartite graphs. Through meticulous theoretical analysis, we demonstrate that BIRD significantly improves time complexity to Õ ( n ), as compared to the previous best one, Õ ( m ), under typical relative error setting and constant failure probability. ( n, m denote the number of nodes and edges respectively.) Extensive experiments confirm that BIRD outperforms existing baselines by orders of magnitude in large-scale bipartite graphs. Notably, our proposed method accomplishes a single-source BHPP query on Orkut using merely 7 minutes.

Between-session reliability of dry-land and in-water tests to measure inter-limb asymmetries in swimmers

ABSTRACT The aims of the present study were to: i) analyse the between-session reliability of dry-land and in-water swimming tests, and ii) investigate the prevalence of meaningful asymmetries in swimming athletes. Twenty-eight swimmers (21 males, 7 females) performed anthropometric, shoulder range of motion (ROM), countermovement jump, shoulder isokinetic torque, and 15-s tethered swimming tests two times, 1 week apart. Inter-limb asymmetries were calculated for each variable. Raw data reliability was determined using the intraclass coefficient correlation (ICC) and the typical error of measurement (TEM), and effect size (ES) was used to determine systematic bias between test sessions. At an individual level, inter-limb asymmetries were compared to the coefficient of variation (CV) to determine whether they were real. The between-session reliability was good to excellent (0.75 to 1.00) for most of the raw data, except for ROM. Between-session ES was predominately “trivial” or “small” for raw data and asymmetries, reinforcing that the values did not change significantly between the sessions. In addition, real asymmetries were seen in some tested metrics, depending on the test. In conclusion, the tested variables presented good levels of between-session reliability and were able to detect real and consistent asymmetries.

Tailor-joining of Ti6Al4V skin with V-shaped assembly error using enhanced PLBW scheme: Keyhole dynamics and metal bridging behavior

Building thin-walled titanium alloy skin using conventional laser beam welding (LBW) frequently suffers from undesirable seam quality due to the V-shaped notch; a typical assembly error occurs after skin rolling with a specific sheet thickness range. This work proposed an improved scheme with metal bridging capacity and liquid film stability to overcome this by executing a pulsed laser beam and spot irradiation in a flat-top mode. Welding was performed on 1.5 mm-thick Ti6Al4V sheets configured in the butt joint with a reserved notch geometry, which is 20 degrees between the groove surface. We also conducted numerical modeling and solutions concerning the heat-flow-phase dynamics using an enhanced ray tracing algorithm. Results show that the as-build weld beads, characterized by middle rippers, slight depression, and edge ridges, present superb continuity and uniformity when applying an average heat input of 40–90 J/mm and a pulse energy of 187.5–750 J. Effective metal bridging across the notch error is achieved at both pulse duration and interval phases due to not only the complete melting of welding side but also the enhanced melt film stability against the surface tension. The cooling of the weld pool starts with a sharp temperature drop at ∼3×105 K/s (on average) during the keyhole collapsing regime, then slows down due to the damped up-down oscillation of the free surface combined with the natural convection-conduction effect. The flow pattern of molten metal changes from squeezing-like to vortexes and finally to a backfilling mode, depending on the evolution of keyhole geometry. Although the keyhole dynamics differs, various process conditions regarding heat input and pulse energy yield effective metal bridging of a single weld spot and sufficient refusion between the adjacent weld spots, ensuring the well-overlapped weld bead formation.

Assessing the individual relationships between physical test improvements and external load match parameters in male professional football players-a brief report.

This study aimed to explore whether a meaningful improvement in physical performance following an in-season strength training intervention can be related to external load match parameters at an individual level in professional male football players. Eight male professional football players (25.4 ± 3.1 years, 184.1 ± 3.4 cm, 79.3 ± 2.2 kg) completed a 10-week strength intervention period in addition to football-specific training and matches. Commonly used physical and external load measures were assessed before and after intervention. Physical performance improvements had to exceed the measurement's typical error and the smallest worthwhile difference (SWD) to be considered meaningful. External load match parameters were assessed before and after the intervention period using SWD and non-overlap of all pairs (NAP) analysis. A Bayesian pairwise correlation analysis was performed to evaluate relationships between changes in physical performance and external load match parameters. Three players displayed meaningful improvements in two to five physical performance measures. However, positive changes exceeding the SWD and positive effects in NAP results were observed for all players in external load match parameters. Kendall's tau correlation analysis showed evidence (base factor >3) for only one correlation (maximum speed - decelerations, τ = -0.62) between the changes in physical performance and external load measures, while the remaining comparisons exhibited no relation. The findings suggest that improvements in physical performance may not necessarily translate to improvements in external load match parameters. Further research, with larger sample sizes, is needed to understand potential mechanisms between acute and chronic physical performance changes and football external load parameters during training and matches.

Energy Expenditure Validation of an Exergame Platform: Ring Fit Adventure Use in Adults with Overweight and Obesity.

Objective: This study aims at comparing the energy expenditure (EE) and heart rate (HR) data from Ring Fit Adventure (RFA) with those from indirect calorimetry (COSMED) and a heart rate monitor (Polar FT7). A secondary goal is to evaluate self-reported enjoyment and perceived effort levels. Materials and Methods: Thirty participants (age = 21.8 ± 2.2; body mass index = 31.8 ± 4.4) were recruited for two laboratory visits. The first visit involved baseline measurements. In the second visit, participants performed a 55-minute ad libitum exercise session with the RFA in adventure mode with moderate difficulty. During this session, EE, HR, perceived effort, and enjoyment of physical activity were recorded. Results: Although no statistically significant overestimation of EE was found between the RFA and the metabolic cart, two-way analysis of variance results show a main effect of condition (RFA vs. Polar FT7) on HR (122.8 ± 20.1 bpm and 129.0 ± 18.6 bpm; P = 0.007; ᶯp2 = 0.235). Based on comprehensive statistical evaluations, including the mean absolute percent error, intraclass correlations, typical error of measurement, and limits of agreement, the data suggest that the RFA provides reliable estimates for EE and HR. Overall, participants enjoyed the game considerably (71.3 ± 5.9/80 arbitrary units), and their reported perceived exertion was low. Conclusion: This study underscores that the RFA values are relatively accurate and precise, and thus it can be safely suggested for individuals with overweight and obesity to adopt an active lifestyle.

Comparing planar quantum computing platforms at the quantum speed limit

An important aspect that strongly impacts the experimental feasibility of quantum circuits is the ratio of gate times and typical error time scales. Algorithms with circuit depths that significantly exceed the error time scales will result in faulty quantum states and error correction is inevitable. We present a comparison of the theoretical minimal gate time, i.e., the quantum speed limit (QSL), for realistic two- and multi-qubit gate implementations in neutral atoms and superconducting qubits. Subsequent to finding the QSLs for individual gates by means of optimal control theory we use them to quantify the circuit QSL of the quantum Fourier transform and the quantum approximate optimization algorithm. In particular, we analyze these quantum algorithms in terms of circuit run times and gate counts both in the standard gate model and the parity mapping. We find that neutral atom and superconducting qubit platforms show comparable weighted circuit QSLs with respect to the system size. Published by the American Physical Society 2024

Effect of conditioning activity absolute intensity on seated shot put performance

Conditioning activities are widely used in sports for improving performance in a subsequent main activity. Therefore, understanding the organization of these exercises is important for athletes. Therefore, the objective this study was to evaluate whether the conditioning activity absolute intensity affects the seated shot put performance. Twenty-four physically active male adults were subjected, every 24 hours apart and in a randomized manner, to the following situations: control (no conditioning activity), seat shot 2 kg ball; seated shot 4 kg ball and; seated shot 6 kg ball. Three minutes after these shots, participants performed the seat shot put main activity (4kg). To record the seat shot put performance, the greatest distance of the six attempts was considered. The shot put distance was greater in conditioning activity compared to the control situation (p &lt; .05). There was no difference in shot put distance among conditioning activity situations (p &gt; .05). In addition, individual analysis using typical error showed that 63% of the participants responded positively to the conditioning activities. In conclusion, despite the beneficial effect of the conditioning activity in relation to the control situation, there was no effect of the absolute intensity of the conditioning activity on shot put performance.

Reliability and validity of a low-cost, wireless sensor and smartphone app for measuring force during isometric and dynamic resistance exercises.

The aim of this study was to investigate the reliability and validity of an affordable wireless force sensor in measuring mean and peak forces during resistance training.A Suiff Pro wireless force sensor (Suiff, Spain) and a MuscleLab force platform (Ergotest, Norway) were used concurrently to assess tensile load and the ground reaction force resulting from an upright row exercise. Thirteen participants (28.2 ± 5.7 years, 76.2 ± 9.6 kg, 178.2 ± 9.2 cm) performed the exercise under three velocity conditions and isometrically. Each condition involved three sets of exercise. Mean (Fmean) and peak (Fpeak) force values from both sensors were collected and compared.Suiff Pro exhibited excellent reliability for Fmean and Fpeak (ICCs = 0.99). When compared to the criterion measures, Suiff Pro showed trivial standardized bias for Fmean (Mean = 0.00 [CI 95% = 0.00 to 0.01]) and Fpeak (-0.02 [-0.04 to 0.00]). The standardized typical error was also trivial for Fmean (0.03 [0.02 to 0.03]) and Fpeak (0.07 [0.05 to 0.09]). Correlations with the MuscleLab force platform were nearly perfect: Fmean (0.97 [0.94 to 0.98]; p<0.001); Fpeak (0.96 [0.92 to 0.97]; p<0.001).The findings demonstrate that the Suiff Pro sensor is reliable and valid device for measuring force during isometric and dynamic resistance training exercises. Therefore, practitioners can confidently use this device to monitor kinematic variables of resistance training exercises and to obtain real-time augmented feedback during a training session.

Reliability and validity of a non-linear index of heart rate variability to determine intensity thresholds.

Exercise intensity distribution is crucial for exercise individualization, prescription, and monitoring. As traditional methods to determine intensity thresholds present limitations, heart rate variability (HRV) using DFA a1 has been proposed as a biomarker for exercise intensity distribution. This index has been associated with ventilatory and lactate thresholds in previous literature. This study aims to assess DFA a1's reliability and validity in determining intensity thresholds during an incremental cycling test in untrained healthy adults. Sixteen volunteers (13 males and 3 females) performed two identical incremental cycling stage tests at least 1week apart. First and second ventilatory thresholds, lactate thresholds, and HRV thresholds (DFA a1 values of 0.75 and 0.5 for HRVT1 and HRVT2, respectively) were determined in heart rate (HR), relative oxygen uptake (VO2rel), and power output (PO) values for both tests. We used intraclass correlation coefficient (ICC), change in mean, and typical error for the reliability analysis, and paired t-tests, correlation coefficients, ICC, and Bland-Altman analysis to assess the agreement between methods. Regarding reliability, HRV thresholds showed the best ICCs when measured in PO (HRVT1: ICC = .87; HRVT2: ICC = .97), comparable to ventilatory and lactate methods. HRVT1 showed the strongest agreement with LA 2.5 in PO (p = 0.09, r = .93, ICC = .93, bias = 9.9 ± 21.1), while HRVT2 reported it with VT2 in PO (p = 0.367, r = .92, ICC = .92, bias = 5.3 ± 21.9). DFA a1 method using 0.75 and 0.5 values is reliable and valid to determine HRV thresholds in this population, especially in PO values.

A Methodological Comparison of Protocols and Analytical Techniques to Assess the Outcome Measures ofSubmaximal Fitness Tests.

Submaximal fitness test (SMFT) outcome measures are frequently collected with a wide array of technologies and methodological approaches. To examine the test-retest reliability of various SMFT outcome measures derived from different protocols and analytical techniques. Twenty-six semiprofessional adult soccer players performed 3 SMFT protocols, including 2 continuous (3min, 11 and 12.8km·h-1) and 1 intermittent (4 × 50m, 18km·h-1) twice, each separated by 7days. Heart-rate (HR) indices (exercise HR, HR recovery)and scapula-mounted (PlayerLoad vector magnitude) and foot-mounted (flight time and contact time, stride length) microelectrical mechanical system-derived variables were collected using different time frames and analytical approaches adopted in the literature and practice. Absolute reliability was quantified as the group mean difference, typical error of measurement, also expressed as the coefficient of variation (where appropriate) and standardized units (ie,d). Intraclass correlation coefficient was used to quantify relative reliability. The highest degrees of reliability were evident for exercise HR (typical error: 1.0%-1.6% points), the vertical component of PlayerLoad (expressed in arbitrary units; coefficient of variation: 5.5%-7.0%), and contact time (coefficient of variation: 1.5%-3.0%). These estimates were not influenced by SMFT protocol or analytical approach. All other measures displayed poorer reliability and/or were different between protocols and analytical methods. SMFT protocols impact the test-retest reliability of various outcome measures; however, exercise HR, verticalPlayerLoad, and contact time (derived from foot-mounted micro-electrical mechanical systems) appear to have stable measurement properties to assist the assessment of aerobic capacity and lower-limb neuromuscular status, respectively.

An implementation of climate-related financial policies to promote a nation’s participation in global value chains: evidence from an international database

PurposeThis study aims to investigate two issues: (1) a nexus between climate-related financial policies (CRFP) and global value chains (GVC) and (2) the government’s policies to help countries enhance the efficient use of CRFP in improving a country’s likelihood to participate in GVC.Design/methodology/approachTo investigate the connection between GVC and CRFP, the authors incorporate that backward participation is measured using foreign value-added, while domestic value-added is used to measure forward participation, quantified as proportions of gross exports. The study analyses yield significant insights across a span of 20 developing countries and 26 developed countries over the period from 2010 to 2020.FindingsRegarding the first issue, the authors affirm the presence of a linear link between GVC and CRFP, implying that involvement in CRFP is advantageous for both backward and forward participation. Furthermore, the authors identify long-term GVC and CRFP cointegration and confirm its long-term effects. Notably, the expression of a linear relationship between GVC and CRFP appears to be stronger in developing countries.Research limitations/implicationsThe study findings, together with previous research, highlight the importance of financial policies relating to climate change (CRFP) in the context of economic growth. Climate change’s consequences for financial stability and GVC highlight the importance of expanded policymakers and industry participation in tackling environmental concerns.Practical implicationsRegarding the second issue, the study findings suggest critical policy implications for authorities by highlighting the importance of financial stability and expanded policymakers in promoting countries' participation in GVC.Originality/valueThis paper investigates the link between GVC performance and CRFP, offering three significant advances to previous research. Moreover, as a rigorous analytical method, this study adopts a typical error model with panel correction that accounts for cross-sectional dependency and stationarity.

Duplicate measures of hemoglobin mass within an hour: feasibility, reliability, and comparison of three devices in supine position

Duplicate measure of hemoglobin mass by carbon monoxide (CO)-rebreathing is a logistical challenge as recommendations prompt several hours between measures to minimize CO-accumulation. This study investigated the feasibility and reliability of performing duplicate CO-rebreathing procedures immediately following one another. Additionally, it was evaluated whether the obtained hemoglobin mass from three different CO-rebreathing devices is comparable. Fifty-five healthy participants (22 males, 23 females) performed 222 duplicate CO-rebreathing procedures in total. Additionally, in a randomized cross-over design 10 participants completed three experimental trials, each including three CO-rebreathing procedures, with the first and second separated by 24 h and the second and third separated by 5–10 min. Each trial was separated by >48 h and conducted using either a glass-spirometer, a semi-automated electromechanical device, or a standard three-way plastic valve designed for pulmonary measurements. Hemoglobin mass was 3 ± 22 g lower (p < 0.05) at the second measure when performed immediately after the first with a typical error of 1.1%. Carboxyhemoglobin levels reached 10.9 ± 1.3%. In the randomized trial, hemoglobin mass was similar between the glass-spirometer and three-way valve, but ∼6% (∼50 g) higher for the semi-automated device. Notably, differences in hemoglobin mass were up to ∼13% (∼100 g) when device-specific recommendations for correction of CO loss to myoglobin and exhalation was followed. In conclusion, it is feasible and reliable to perform two immediate CO-rebreathing procedures. Hemoglobin mass is comparable between the glass-spirometer and the three-way plastic valve, but higher for the semi-automated device. The differences are amplified if the device-specific recommendations of CO-loss corrections are followed.

The effect of measurement error on the positive predictive value of PSW methods for SLD identification: How buffer zones dispel the illusion of inaccuracy

Patterns of Strengths and Weaknesses (PSW) methods are widely used for identifying specific learning disabilities (SLDs). Several researchers, however, have reported that the diagnostic accuracy of PSW methods is unacceptably low when strict thresholds were used to identify students with SLDs. We believe these findings give a misleading impression of the magnitude of the diagnostic errors that are likely to arise in PSW assessments. In a simulation study of 10 million cases using a simplified PSW method for demonstration, most of what have been called diagnostic errors were cases in which observed scores and true scores fell on opposite sides of a strict threshold but were still within a buffer zone the size of a typical measurement error. Because small score differences do not result in meaningfully different case conceptualizations, the use of buffer zones reveals that previous estimates of the diagnostic accuracy of PSW methods are misleadingly low. We also demonstrate that diagnostic decisions become increasingly reliable when observed scores are comfortably distant from diagnostic thresholds. For practitioners, we present a flowchart and practical guidelines to improve the accuracy and stability of SLD identification decisions.

Reliability of recovery heart rate variability measurements as part of the Lamberts Submaximal Cycle Test and the relationship with training status in trained to elite cyclists

PurposeTo determine if post-exercise heart rate variability, in the form of logged transformed root mean square of successive differences of the R–R intervals (LnRMSSD) can be measured reliably during the recovery from a submaximal cycle test and what the relationship of LnRMSSD is with training status of the cyclists.MethodsFourteen male cyclists participated in the reliability part for the study, which included performing six Lamberts Submaximal Cycle Test (LSCT), during which recovery LnRMSSD was measured over 30 s (LnRMSSD30 s), 60 s LnRMSSD60 s)and 90 s LnRMSSD90 s). In addition, fifty male and twenty female cyclists completed a peak power output (PPO) test (including VO2peak) and 40 km time trial (40 km TT) before which they performed the LSCT as a standardized warm-up. Relationships between the LnRMSSD and PPO, VO2peak and 40 km TT time were studied.ResultsDue to the design of the LSCT, submaximal heart and breathing rate were similar at the end of stage 3 of the LSCT, as well as during the recovery periods. The highest reliability was found in LnRMSSD60 s (ICC: 0.97) with a typical error of the measurement (TEM: 5.8%). In line with this the strongest correlations were found between LnRMSSD60 s and PPO (r = 0.93[male]; 0.85[female]), VO2peak (r = 0.71[male]; 0.63[female];) and 40 km TT (r = – 0.83[male]; – 0.63[female]).ConclusionsLnRMSSD60 s can be measured reliably after the LSCT and can predict PPO, VO2peak and 40 km TT performance well in trained-to-elite cyclists. These findings suggest that recovery LnRMSSD can potentially play an important role in monitoring and fine-tuning training prescriptions in trained-to-elite cyclists.