<P>According to the U.S. Department of Transportation, 31 million Americans traveled overseas in 2007, excluding Mexico and Canada. Children are accompanying their parents to overseas destinations more often for both business- and pleasure-related travel, with an estimated 1.9 million children traveling overseas each year. Children who travel to tropical destinations are at risk for infections not typically encountered in the United States. In addition, the epidemiology of health issues may vary in this subpopulation due to age-specific variations in immunity and behavior. Data on the etiology of infectious diseases in pediatric travelers are limited. However, several small studies have demonstrated that after common respiratory viral infections, diarrheal illnesses, malaria, dengue fever, and typhoid fever are most commonly reported. More recently, research involving the GeoSentinel Surveillance Network, a global infectious disease reporting system that includes information on more than 50,000 ill travelers, has provided additional information on travel-related illnesses. One study using this database assessed how commonly fever is reported as a chief reason for seeking medical care. Of the 24,920 patients that met inclusion criteria, 5% to 6% of whom were younger than 20 years of age, 6,957 travelers or 28% included fever as the chief complaint. Of those with fever, 35% had a febrile systemic illness, 15% had diarrheal disease, and 13% had fever in conjunction with a respiratory illness. Malaria was diagnosed in 21% of those with fever, making it the most common specific diagnosis. Therefore, it is essential that healthcare providers who may encounter children who have visited a tropical destination have a basic understanding of initial evaluation and treatment of travel-related disorders.</P> <H4>ABOUT THE AUTHORS</H4> <P>Andrea Summer, MD, MSCR, is with the Department of Pediatrics, Medical University of South Carolina, Charleston. William M Stauffer MD, MSPH, is with the Department of Medicine, Infectious Diseases and International Medicine; and the Department of Pediatrics, Infectious Diseases, University of Minnesota, Minneapolis.</P> <P>Address correspondence to: Andrea Summer, MD, MSCR, Medical University of South Carolina, Department of Pediatrics, 135 Rutledge Avenue, PO Box 250561, Charleston, SC 29425; fax 843-876-8709; or e-mail <a href="mailto:summera@musc.edu">summera@musc.edu</a>.</P> <P>Dr. Summer and Dr. Staufer have disclosed no relevant financial relationships.</P> <H4>EDUCATIONAL OBJECTIVES</H4> <OL> <LI>Recognize the diverse infectious pathogens that must be considered in an ill child who recently returned from international travel.</LI> <LI>Discuss the importance of rapidly evaluating fever in returned travelers from tropical areas.</LI> <LI>Describe the general approach for efficiently identifying infections in ill returning travelers.</LI> </OL>
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