Triple Helix Approach Research Articles

A Comprehensive Model for Innovation Ecosystems

Abstract Research on innovation ecosystems is mostly approached from the point of view of institution-oriented aspects, which typically focus on the structural elements of innovation systems. However, this perspective has limitations to describe a really functioning innovation system, as it does not take into account its complex nature of dynamics and the functional features. The authors run research on models of innovation ecosystems based on complexity theory principles. The presented perspective, based on complexity theory, takes into account not only the structural and the complex but also the dynamic feature of the innovation ecosystems, still using the triple helix approach as a basis. The objective of the article is to present a system model framework for innovation ecosystems, that can be used for development of technology and science parks management models. The approach of the research is based on literature review and discussion of relevant results, followed by explanation and concluding a possible innovation ecosystem framework model, finally demonstrated its interpretation through a specific case. In its first part, the article gives a general overview on complex systems from point of related findings on innovation ecosystems. Based on literature review, the preliminary analysis of the authors in the subject is given. Then, the relevant model features are described, then and the proof of the concept is explained according to the research. The descriptive features of complex systems based on the referenced papers are used to interpret the proposed model. The main outcome of the article is a comprehensive innovation ecosystem model as a tool to understand and analyse such systems based on actors, functions and key factors. The authors demonstrated in the article that features of complex systems not only help describing innovation ecosystems but also support defining key model elements. An empiric case of ZalaZONE Technology Park was shown related to the presented innovation ecosystem model. Finally, the next steps of the model development are outlined and advice is concluded for application of the model in the practice and in further research. The novelty of the article is pointing out that the simple model of triple helix and the complexity approach as a view for modelling the real circumstances, can be well-combined to outline a comprehensive model for innovation ecosystems.

Bridging workforce skills gaps in rural America amid ‘the great resignation' by leveraging a triple helix collaboration

The COVID-19 pandemic dramatically impacted the job market through a surge in layoffs and the mass resignation of employees leading to the emergence of ‘The Great Resignation’. This study explores the perspectives of employers regarding skills gaps and hiring challenges with a focus on rural communities. A collaboration led by a prominent rural university department of Community and Workforce Development included industry partners, governmental agencies, a partner university, primary and secondary schools (K-12), vocational institutions, Chambers of Commerce, and Small Business Development Centers. Their objective was to examine the gap between employer needs and worker readiness. Leveraging the Triple Helix approach, a grant was awarded to fund a stackable pathway skills development program for high-demand industries in a rural five-county area. This program, the Industry Engaged Workplace Ready Program Model, is a two-phase, rapid-response approach for meeting emergent workforce needs by providing accessible training, education, networking, and mentoring to employable candidates. Findings revealed success in the program with mixed outcomes and room for program revision.

Implementation of the Triple Helix Model in Increasing Economic Opportunities for Waste Management in Pangkalpinang City

This research reviews waste management problems in Pangkalpinang City, Indonesia, which is facing increasing waste volumes and suboptimal management. In an effort to overcome this problem, research uses a collaborative Triple Helix Model approach involving government, industry and universities. By combining the resources and competencies of these three parties, the research aims to develop a more effective and sustainable waste management model in Pangkalpinang. Through analysis of involvement and collaboration between government, industry and universities, this research explores the potential of the Triple Helix approach in overcoming waste management problems in the city. The research results show that the implementation of the Triple Helix Model has had a positive impact on waste management in Pangkalpinang City with various programs and initiatives that have been implemented. Recommendations for waste recycling programs are prioritized as an effective solution in maintaining environmental sustainability and creating new economic opportunities. However, there are still challenges such as lack of public awareness, limited resources, and technical obstacles that need to be overcome. By continuing effective collaboration between government, industry, academics and the community, it is hoped that waste management can continue to be improved and support sustainable development in Pangkalpinang City.

Meeting Report of the Second Symposium of the Belgian Society for Viruses of Microbes and Launch of the Phage Valley.

The second symposium of the Belgian Society for Viruses of Microbes (BSVoM) took place on 8 September 2023 at the University of Liège with 141 participants from 10 countries. The meeting program covered three thematic sessions opened by international keynote speakers: two sessions were devoted to "Fundamental research in phage ecology and biology" and the third one to the "Present and future applications of phages". During this one day symposium, four invited keynote lectures, nine selected talks and eight student pitches were given along with thirty presented posters. The president of the Belgian Society for Viruses of Microbes, Prof. Yves Briers, took advantage of this symposium to launch the Phage Valley concept that will put the spotlight on the exceptionally high density of researchers investigating viruses of microbes as well as the successful triple helix approach between academia, industry and government in Belgium.

Triple Helix approach to innovation in Rwanda's agriculture resulted in a partnership between educational institutions and a private firm producing clean seed potatoes

Triple Helix approach to innovation in Rwanda's agriculture resulted in a partnership between educational institutions and a private firm producing clean seed potatoes

A Triple Helix Approach to Address Social and Learner Support Needs in Schools and Communities

A Triple Helix Approach to Address Social and Learner Support Needs in Schools and Communities

Adaptation strategies for dealing with global atmospheric change in Mediterranean agriculture: a triple helix approach to the Spanish case study

Adaptation strategies for dealing with global atmospheric change in Mediterranean agriculture: a triple helix approach to the Spanish case study

Supply chain solutions for essential medicine availability during COVID-19 pandemic

PurposeThis study aims to document students’ supply chain solutions developed through the internship hackathon program. The study profiled innovative solutions developed by university students in Kenya to solve health supply chain logistics challenges during and beyond COVID-19. This is done by exploring students’ experience in developing sustainable logistics and supply chain management capacity-building programs in a low-middle-income country (LMIC).Design/methodology/approachThis study used a qualitative approach to explore the experiences and perceptions of students and mentors who participated in a hackathon program. The study followed a cross-sectional descriptive survey design, collecting data from the participants through online questionnaires. The data were analyzed and presented using thematic analysis and narrative techniques.FindingsFindings provide preliminary evidence for narrowing the gap between theory and practice through a hackathon internship blended with a mentorship program. Assessment of this program provides evidence for developing solutions toward ensuring the availability of essential medicine in LMICs during a pandemic such as COVID-19 by students. The profiled solutions demonstrate a broader perspective of innovative solutions of university students, mentors and potential opportunities for a triple helix approach to innovation for health supply chain system strengthening.Research limitations/implicationsThis original study provides evidence for advancing contribution to developing innovative solutions through partnerships between investors, universities and industry practitioners interested in mentoring students in the health-care supply chain during COVID-19 in LMICs. Specifically, contingency factors that affect the implementation of innovative programs during and beyond global pandemics such as COVID-19 by students’ innovators are identified, and implications for policy action are discussed based on the praxis of sensemaking.Practical implicationsThis study examines a novel approach that combines internship, mentorship and hackathon projects for logistics and supply chain students in LMICs. The approach aims to bridge the gap between theory and practice and to create innovative solutions for essential medicines during and after COVID-19. The study urges more resources for supporting such programs, as they benefit both academia and industry. The study also argues that hackathon internship programs can help the logistics and supply chain industry adapt to the post-pandemic era. The study offers insights for investors, universities and practitioners in the health-care industry.Originality/valueThis study shows how to develop innovative solutions for the health-care supply chain during COVID-19 in an LMIC through partnerships between investors, universities and industry practitioners who mentor students. The study identifies the contingency factors that influence the success of such programs during and beyond global pandemics such as COVID-19 and discusses the policy implications based on the sensemaking praxis of the student innovators.

Implementation Analysis of Army Polytechnic Research Management for The Armament Development of The Indonesian Army

Implementing Vocational Higher Education in The Army Polytechnic (Poltekad) has used the Triple Helix approach: universities, the private sector, and the government. In its development, Poltekad contributes to the direction of the development of the Army’s technological innovation field. Based on observations of the results of Poltekad research, it has yet to be utilized optimally in fulfilling Army equipment and weapons. In the last three years, 2020–2022, 163 final research assignments were recorded by Poltekad students, and 40 research by Poltekad lecturers. However, only eight lecturers’ research has become research models with the potential for defense and development in the Army. This study uses a qualitative research method, specifically a case study. The study results show that Poltekad has not been able to play a role as a research university, but is still limited to its function as a vocational education institution in the technology field. The allocation of research funds for Poltekad is still relatively small compared to the benefits of research to support the development of Army Armaments. The research themes of lecturers and students are not entirely following the needs of the development of Indonesian Army weaponry technology. The absence of a Poltekad external monitoring and evaluation team for research programs, limited educational laboratory facilities, and qualified lecturers as researchers in the Poltekad environment are several reasons for optimizing the utilization of Poltekad research results which cannot be carried out downstream in the implementation of production activities carried out by the Defense Industry in Indonesia as is stated in the Poltekad vision. Poltekad, as a Research University, needs to pay attention to elements, such as 1) budgeting, 2) Research Programs, 3) monitoring, and evaluation, 4) researcher competence, 5) facilitation facilities, 6) information and communication systems, and 7) scientific publications. Downstreaming the themes to utilize research results is carried out according to needs and developments.

SP-3: PRECISION MEDICINE

Precision Medicine is one of the most impactful global opportunities in healthcare. We can debate the name, whether it is precision, stratified or personal but at the highest strategic level, we all share a common goal to enable a world where healthcare is informed by each person unique clinical, molecular and lifestyle information. Precision Medicine will spur a revolution in healthcare, bringing the prospects of earlier, pre-symptomatic diagnosis, more effective treatment, significant cost savings for the NHS and all the above combined with better patient outcomes. Moreover, Precision Medicine will reach the global market value of £134 billion by 2025 thus contributing to unprecedented developments in Life Sciences industry, including new jobs creation, and a significant economic growth. The UK is in a prime position to lead on Precision Medicine globally due to the NHS facilitating advanced health data management, excellent genomics and other omics, new imaging modalities and major advances in the artificial intelligence applied to diagnostics. All the above is supported by the triple helix approach, which involves close collaborations among academic researchers, the NHS and industry. The Covid-19 pandemic has made a major contribution to the UK molecular diagnostic capability. This legacy includes very high throughput laboratories, which should become key building blocks for the UK cutting edge Precision Medicine strategy for the next decade and beyond.

Cooperation with the Triple Helix and corporate environmental innovation

This paper investigates the possible synergic effect of the cooperation between firms and the main agents of the Triple Helix approach (academia, industry and government) on corporate environmental innovation. The results of analysing a broad sample of Spanish firms from various sectors (38,269 observations) over a 9-year period show that cooperation between firms and Triple Helix agents, both individually and jointly, increases the likelihood of corporate environmental innovation. Indeed, the more Triple Helix agents involved in cooperation with firms, the greater the likelihood of corporate environmental innovation. In addition, for the same number of Triple Helix agents involved, the influence of cooperation on corporate environmental innovation depends on the type of agents. Consequently, the paper provides empirical evidence of the existence of a synergic effect of cooperation on environmental innovation.

Measuring the development of innovations districts through performance indicators: 22@Barcelona Case

Innovation Districts are rising as the banners of the new urban, economic, and social paradigm and as a solution to the renaissance of inner cities since they expedite the creation and commercialization of new ideas which leverage the city goals and its technologic and economic attributes. The configuration of accurate indicators to measure the degree of achievement of the innovation district goals is one of the main requirements to ensure district proper development. Even when the study of innovation districts is a topic that is increasingly under study, little is still known about the insight, and it is still needed tools that favor their evolution and development. The aim of this paper is two-fold: on the one hand, it seeks to collect and analyze the indicators that have been used in literature to measure the degree of maturity over the course of the 20-year existence of the 22@Barcelona, an area of innovation that transformed an old industrial district into a knowledge-based one. On the other hand, guided by the four dimensions of the Knowledge Base Urban Development theory and the main actors that make up Triple Helix approach, the paper designs a framework of indicators in the four spheres that shape the regeneration of the district, that is, urban, economic, social and governance. As we shall see, a total of 47 indicators are proposed, indicating for each of them: the environment in which it is applied, the main purpose to which it responds, and the main actor with the greatest power of action over it.

Association of Adiponectin Levels with Polycystic Ovarian Syndrome

: This paper describes the opportunities that blockchain technology applied to product traceability might offer to firms of Made in Italy against counterfeiting of their products, and the challenges to the adoption of blockchain technology in these firms, especially SMEs. The focus is on the Italian Region Marche which is characterised by a prevalence of firms specialised in the Made in Italy. The paper proposes a triple helix approach to facilitate the diffusion of blockchain technology in the Marche Region and individuates policies and non-academic actors at the regional level that could help SMEs to know and adopt this innovative technology.

A Triple Helix Approach for the Diffusion of Blockchain Technology against Counterfeiting of Made in Italy Products in SMEs of the Marche Region

A Triple Helix Approach for the Diffusion of Blockchain Technology against Counterfeiting of Made in Italy Products in SMEs of the Marche Region

Pan genome based reverse vaccinology approach to explore Enterococcus faecium (VRE) strains for identification of novel multi-epitopes vaccine candidate

Enterococcus faecium is regarded as fourth most emerging common pathogen causing hospital acquired infections (HAIs), with high mortality rate, especially in children, elderly and immunocompromised patients. Recently, due to the emergence of E. faecium resistant strains especially vancomycin resistance (VRE) and their continuously growing resistivity to antibiotics, design of safe vaccine remains a choice for its control. Alternative control through vaccination has received much attention, but there is no clinically approved vaccine against this pathogen. Therefore, in current study we have applied a triple helix approach i.e., Pan-genome, subtractive genome and reverse vaccinology to identify and design potential vaccine candidates and multiepitope-based vaccine (MEV) construct against E. faecium (via core genome analysis from 216 strains). In this study, only 2 outer membrane proteins were identified through genome subtraction of resistant strains genes against human and essential proteins. Subsequently, phosphate ABC transporter substrate binding protein (Psts) was selected as a promiscuous vaccine candidate to develop a potent vaccine model. A final of four epitopes from CD8 + T-cell, CD4 + T-cell epitopes, and B-cell were shortlisted from outer membrane protein with highly antigenic, IFN-γ inducer, and overlapping characteristics for the construction of twelve vaccine models. The V3 construct was found to be highly immunogenic, non-toxic, non-allergenic, highly antigenic and most stable in terms of molecular docking and simulation studies against six HLAs, TLR2, and TLR4 complex. So far, this protein and multiepitope have never been characterized as vaccine targets against E. faecium. The current study proposed V3 as a significant vaccine candidate that could help the scientific community to treat E. faecium infections.

Contribution of semi-organic shallot to sustainable value chain: case study of marginal land in Selopamioro village, Bantul, Yogyakarta, Indonesia

Shallot is one of three main vegetable commodities in Indonesia, highly potential to be developed, both in terms of consumption and trade. However, shallot from sustainable cultivation is still scarcely available in the market. Therefore, this study aims to analyse the semi-organic shallot value chain in order to identify constraints on production and marketing, also to assess its value chain sustainability performance, with case of marginal land in Selopamioro village, Bantul district, Yogyakarta. The research involves multi-stakeholders along the chain, including three farmer groups i.e. Lestari Mulyo, Sekar Mulyo, and Bumi Mukti. These groups have consistently developed semi-organic shallot production for the past few years, using different bulb varieties, due to their soil characteristics. Snowball sampling is applied in mapping the value chain actors, followed with survey, key informant interview within guided questionnaire, and market observations. Data analysis covers descriptive analysis, PESTEC analysis for constraint identification and improvement recommendation, while value chain sustainability performance is assessed through selected indicators of economic, social, and environment related to the study area. Results describe actors, supporters, and influencers of the existing value chain. In terms of production constraints, results identify: poor marginal land fertility, same time harvesting, discontinuous supply, impatient farming activities, women role equality in farming activities, lack of processing sources, virus contamination risk, longer seedling, and limited source for shifting fuel into electrical machineries. As marketing constraints, results identify: on farm government focus, lack of selling skill and sustainable commodity campaign, unreliable off-takers linkage, limited alternative market information, consumer price sensitivity, verbal agreement transaction, minor young farmer membership, poor e-commerce skill, weak branding effort and processing focus, and business unit unavailability at farmer group. Recommendation highlights the triple helix approach in strengthening the collaboration within the chain. Further the value chain is considered sustainable, with sustainability performance of the value chain related to Lestari Mulyo and Sekar Mulyo is good, and Bumi Mukti is moderate.

Examining the roles of universities in place-based industrial strategy: which characteristics drive knowledge creation in priority technologies?

ABSTRACT Industrial strategies designed to promote innovation in a set of priority technologies through university–industry collaboration essentially institutionalize a triple helix approach to economic development. Yet, treating universities as a generic resource leaves a question mark as to which institutions are most likely to be most useful. In addition, prior evidence of uneven regional distribution of research income in these technologies suggests that place-based interventions may merely lock in pre-existing inequalities. Therefore, by controlling for spatial and temporal variations among UK universities, this paper examines whether their ability to generate knowledge in these priority technologies is dependent upon their entrepreneurial or engaged nature, and strategic orientation. Using data from the UK Higher Education Business & Community Interaction (HE-BCI) survey, the analysis finds that entrepreneurial activities such as higher levels of licensing income, start-ups and patents are associated with higher levels of research income in these priority technologies. Furthermore, higher levels of income from engagement with businesses through collaboration and contract research are also associated with higher research income in these priority technologies, while strategic orientation has no effect.

Institutional development of circular economy in Russia and St. Petersburg

The term "circular economy" appeared relatively recently in Russia. Interest to the circular economy and the number of publications is growing. The concept of circular economy is very closely related to the green economy, bioeconomics, and low-carbon economy, which are based on moving away from fossil fuels and the development of new technologies. However, in Russia, most often circular economy means recycling system. The principles of circular economy are aimed at the economic, social, and environmental well-being of people. Experts identify factors that promote and hinder the development of circular economy in Russia. Issues of sustainable development, circular economy and energy transition are actively discussed by representatives of government, business and science at international and all-Russian forums. The principles of circular economy will allow achieving several Sustainable Development Goals. The circular economy is one of the key factors in achieving carbon-free energy goals. In St. Petersburg, profile committees, centers and associations are actively working in this direction. Consortia of international projects of most programs are formed from partners based on a triple helix approach- representatives of government, business and universities. The international projects of cross–border cooperation programmes "South-East Finland - Russia", "Estonia - Russia" and the INTERREG Baltic Sea region are considered. Pilot sites are being implemented within the framework of many international projects, with the possibility of further replication of successful experience. The legislative base of Russia and St. Petersburg in the field of circular economy is considered in detail.

3D magnetotelluric modeling using high-order tetrahedral Nédélec elements on massively parallel computing platforms

We present a routine for 3D magnetotelluric (MT) modeling based upon high-order edge finite element method (HEFEM), tailored and unstructured tetrahedral meshes, and high-performance computing (HPC). This implementation extends the PETGEM modeller capabilities, initially developed for active-source electromagnetic methods in frequency-domain. We assess the accuracy, robustness, and performance of the code using a set of reference models developed by the MT community in well-known reported workshops. The scale and geological properties of these 3D MT setups are challenging, making them ideal for addressing a rigorous validation. Our numerical assessment proves that this new algorithm can produce the expected solutions for arbitrarily 3D MT models. Also, our extensive experimental results reveal four main insights: (1) high-order discretizations in conjunction with tailored meshes can offer excellent accuracy; (2) a rigorous mesh design based on the skin-depth principle can be beneficial for the solution of the 3D MT problem in terms of numerical accuracy and run-time; (3) high-order polynomial basis functions achieve better speed-up and parallel efficiency ratios than low-order polynomial basis functions on cutting-edge HPC platforms; (4) a triple helix approach based on HEFEM, tailored meshes, and HPC can be extremely competitive for the solution of realistic and complex 3D MT models and geophysical electromagnetics in general.

Analisis Model Tripel Helix Dalam Pengembangan Ekonomi (Studi Pada IKM Kerajinan Perak Mojokerto)

Creative economy development aims to develop human resources so that they can compete with reliable quality. Rural areas, especially the Batankrajan Village area, are one of the areas in Mojokerto Regency that have the potential of creative human resources to improve the welfare of the local community. Batankrajan village and is the center of the silver industry which is quite potential as a competitive product and Mojokerto's leading commodity. The aims of this study were (1) to identify the conditions and needs for product development and market development of the craftsmen/performers of the silver craft business in Senta Batankrajan, Mojokerto, East Java, (2) to identify the problems faced by the craftsmen of silver crafts IKM in Mojokerto, East Java, especially in increasing competitiveness, (3) Analyzing the triple helix model in the development of the creative economy as a driving force for Mojokerto silver handicraft products to increase local innovative and creative products that are unique to the region and have high added value and are able to become regional icons. This research also identifies strengths, weaknesses, opportunities and threats that can be used as information to map the strengths and weaknesses of creative industry players so that strategies for developing the right Triple helix model can be formulated for business actors. This research produces an economic/creative industry model with a Triple helix approach that provides a role for stakeholders (government, universities and business actors) in advancing the creative industry in rural areas, especially the silver industry in the center of Batankrajan, Mojokerto. Several recommendations and the framework for developing the Triple Helix model in the development of the creative economy include: Institutional strengthening, through Joint Business Groups, in order to invest in product development and market penetration as well as facilitate the establishment of access to financial sources and market access, the creation and establishment of intensive communication between government, universities and creative industry players, as well as the establishment of community forums that involve the government, universities in the Mojokerto area and do not rule out universities outside Mojokerto as well as industry players that function as communication forums and as a means of coaching and training.