Transmission Of Electrical Signals Research Articles

Reverse Synchronous Transmission of Electrical Signals Based on Parallel Injection and Series Pickup

To eliminate the interference with the transmission of electrical signals, this paper puts forward a reverse synchronous transmission (RST) control method based on parallel injection and series pickup. Firstly, the synchronous transmission mechanism of electrical signals was analyzed, followed by the design of the framework and workflow of signal transmission. Next, an RST channel model was established for electrical signals, and the transmission parameters were configured based on the transmission properties of these signals. Through alternative current (AC) impedance analysis, the Laplace transform was performed on the transmission loop to increase the voltage of the transmission channel, and to elevate the signal-to-noise ratio (SNR) of the voltage across the resistor. Finally, the voltage comparator was adopted to obtain the digital information of the baseband signal, and the power signal was transmitted to the RST channel, completing the RST control of electrical signals. The experimental results show that the transmission speed of the system was 0.7488, and the reverse transmission of electrical signals was only delayed by 5ms, when the intensity of electromagnetic radiation was 2.0μT. Through parallel injection and series pickup, the proposed system can effectively realize the RST of electrical signals, without changing the topology of the transmission system.

An Improved maintenance method for marine electrical equipment based on the Internet of Things

Due to the influence of high temperature and high humidity, the failure rate of marine electrical equipment is higher than that in other situations. The stability of the electrical equipment of ships is of vital importance to the safety of navigation. Traditional electrical maintenance methods have the problem of lagging in response to equipment fault detection and feedback, which is caused by the signal transmission mode. This article applies the Internet of Things technology to the maintenance of marine electrical equipment, which can improve the performance of the maintenance method. Firstly, the fault detect program architecture is adjusted and optimized. The fault sensing modules are placed in the electrical equipment. The traditional electrical signal transmission mode is replaced by the network transmission mode. Then, the fault signal anti-jamming algorithm is used to optimize the compensation calculation of the alarm signal of the electrical equipment fault point to achieve the effect of enhancing the signal sensitivity; finally, the fault detection sensitivity of the proposed method is tested through experiments, and the data shows that the design method is better than the traditional maintenance method.

Neuronal functions of clathrin-associated endocytic sorting adaptors – from molecules to disease

Abstract Communication in the central nervous system is based on the transmission of electrical signals at specialized junctions between nerve cells termed synapses. During chemical neurotransmission, tiny membrane spheres called synaptic vesicles that are packed with neurotransmitters elicit a postsynaptic response by fusing with the presynaptic membrane and releasing their content into the synaptic cleft. Synaptic vesicle fusion is followed by the reuptake of the membrane by endocytosis and the local reformation of functional synaptic vesicles within the presynaptic compartment to sustain further rounds of neurotransmitter release. Here, we provide an overview of the clathrin-associated endocytic adaptor proteins that help to sort and recycle synaptic vesicles during presynaptic activity. These adaptors also serve additional functions in the turnover of defective or aged synaptic components and in the retrograde axonal transport of important signaling molecules by regulating the formation or transport of autophagosomes. Endocytic adaptors thus play multiple roles in the maintenance of synaptic function. Defects in their expression or function can lead to neurodegenerative and neurological diseases.

Probing myelin content of the human brain with MRI: A review.

Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured by myelin-insulating sheaths surrounding axons. Human cognition, sensation, and motor functions rely on the integrity of these layers, and demyelinating diseases often entail serious cognitive and physical impairments. Magnetic resonance imaging radically transformed the way these disorders are monitored, offering an irreplaceable tool to noninvasively examine the brain structure. Several advanced techniques based on MRI have been developed to provide myelin-specific contrasts and a quantitative estimation of myelin density in vivo. Here, the vast offer of acquisition strategies developed to date for this task is reviewed. Advantages and pitfalls of the different approaches are compared and discussed.

Research on Contact Performance of Aviation Electrical Connector under Atmospheric Turbulence

Electrical connectors are the basic components of the electric system in automobiles, aircrafts and ships to realize the current and electrical signal transmission. In the aviation electrical system, the electrical connectors are indispensable supporting devices accessories, which play important roles in connecting electrical system, monitoring and controlling equipment, and provide a guarantee for the reliable transmission of electrical signals between the aviation equipment and system. Whether aviation electrical connectors work reliably directly affects the safety and reliability of the entire aircraft aviation system. The random vibration of aircraft caused by turbulence during flight is one of the main factors affecting the contact performance of the electrical connectors. In this paper, the contacts of the circular four-slot three-pin electrical connectors were chosen as the research specimens. The theoretical model of the contact force for contacts of electrical connectors was established. The test method for contact force measurement was determined. According to the test scheme, the detecting device for the contact force and contact resistance of the electrical connectors was designed, and the turbulence test of the electrical connectors was carried out. Through the analysis of the test data, the influence rule of the turbulence degree, flight speed and flight height on the contact force and contact resistance of the aviation electrical connectors was obtained.

Numerical analysis of two new finite difference methods for time-fractional telegraph equation

Fractional telegraph equations are an important class of evolution equations and have widely applications in signal analysis such as transmission and propagation of electrical signals. Aiming at the one-dimensional time-fractional telegraph equation, a class of explicit-implicit (E-I) difference methods and implicit-explicit (I-E) difference methods are proposed. The two methods are based on a combination of the classical implicit difference method and the classical explicit difference method. Under the premise of smooth solution, theoretical analysis and numerical experiments show that the E-I and I-E difference schemes are unconditionally stable, with 2nd order spatial accuracy, \begin{document}$ 2-\alpha $\end{document} order time accuracy, and have significant time-saving, their calculation efficiency is higher than the classical implicit scheme. The research shows that the E-I and I-E difference methods constructed in this paper are effective for solving the time-fractional telegraph equation.

Glutamate-Induced Electrical and Calcium Signals in the Moss Physcomitrella patens.

The mode of transmission of signals between plant cells is an important aspect of plant physiology. The main role in the generation of long-distance signals is played by changes in the membrane potential and cytoplasm calcium concentration, but the relationship between these responses evoked by the same stimuli in the same plant remains unknown. As one of the first plants that colonized land, the moss Physcomitrella patens is a suitable model organism for studying the evolution of signaling pathways in plants. Here, by the application of glutamate as a stimulus, we demonstrated that electrical but not calcium signals can be true carriers of information in long-distance signaling in Physcomitrella. The generation of electrical signals in a form of propagating transient depolarization seems to be dependent on the opening of calcium channels since the responses were reduced or totally blocked by calcium channel inhibitors. While the microelectrode measurements demonstrated the transmission of electric signals between leaf cells and juvenile cells (protonema), the fluorescence imaging of cytoplasmic calcium changes indicated that calcium response occurs only locally-at the site of glutamate application, and only in protonema cells. This study indicates different involvement of glutamate-induced electrical and calcium signals in cell-to-cell communication in these evolutionarily old terrestrial plants.

The effect of isolation in controlling the variability of point connected structures with uncertain structural attachments

As the demand for the transmission of electric power and communication signals in automotive and aerospace vehicles increases, so does the number of structures comprising simplified one-dimensional attachments, such as electrical cabling, affixed to a host plate like primary structure. These attachments are typically uncertain in their geometric or material properties, potentially affecting the response of the built-up structure. Difficulties then arise in the prediction of the response of the assembly. This study shows how the variability, due to the uncertain attachments, might be reduced by considering flexible connections. A mobility analysis compares systems connected with either rigid links or elastic springs. A frequency is identified at which the assembly dynamically uncouples; the effect on the host response variability due to the uncertain attachment decreases above this frequency with a reduction of the order of 60 dB in the coefficient of variation. This uncoupling or effective isolation frequency can be simply estimated from the mobility of the elastic connection and the properties of the nominal structural attachment. For design purposes, this frequency can be adjusted to achieve a more predictable response above a given frequency.

An injectable high-conductive bimaterial scaffold for neural stimulation

Neurological recovery is difficult due to limited axonal regeneration and the limitations of autograft therapeutics in repairing peripheral nerve defects. Alternatively, the implantable nerve guidance conduit represents a promising approach for the nerve regeneration of especially large injury gaps. Herein, we presented an easily injectable and highly conductive, tissue engineering scaffold for supporting nerve cells growth and promoting neural differentiation. The ultra-flexible conductive scaffold was prepared by the combination of PCL-based micro-grid via melt electrowriting (MEW) with a nanolayer of gold via sputter coating, which shows good mechanical properties (including high flexibility and recoverability) and high conductivity. The conductive interface acts as a bridge for electrical signal transmission between nerve cells under electrical stimulation, which significantly enhances neural differentiation and improves the neurite outgrowth. Specifically, compared with the PCL group, the neurite length of the 50 Au-PCL and 80 Au-PCL groups increased by nearly 10 and 15 times respectively, after 10 days of culture without ES treatment. Furthermore, as the increase of Au coating thickness, the promotion of the ES effect was further improved. The 80 Au-PCL group showed the highest average neurite length and neurite number per cell compared with PCL (11 times), 20 Au-PCL (9 times), 50Au-PCL (3 times) after ES treatment for 5 days (one hour per day). Overall, our Au-PCL bimaterial scaffold is a promising nerve repair material because of its suitable injectability, high conductivity, biocompatibility, and powerful ability to promote neural stimulation.

Nerve and Blood Vessel Wiring in Endometriotic Peritoneal Lesions

Detection of unique nerve fibres in the endometrium of women with endometriosis and subsequently in their peritoneal lesions has led to increased interest in studying their relationship with infertility and pain. Blood vessels and nerves fibres course throughout the body in an orderly pattern, often alongside one another. Although superficially distinct, the mechanisms involved in wiring neural and vascular networks seem to share similarities. We found that nerve fibres and blood vessels traverse the endometriotic peritoneal tissue in slightly different ways with variations in length densities (Lv), branch point density (Bv), segment length between branch points (Lv/Bv) and capillary radial diffusion distance r(diff). The capillary radial diffusion distance r(diff) and the spatial co-localisation distance in conjunction with nerve fibres fell within range for the facilitation of the physiological diffusion and transfer of molecular substances and the transmission of electrical signals to co-ordinate tasks within the endometriotic peritoneal lesion.Biological systems exist and operate in a three-dimensional environment and blood vessels and nerve trunks often travel in close apposition through many tissues; therefore, it was a priority to assess (CD31+) blood vessel and (PGP9.5+) nerve fibre three-dimensional structural features from qualitative and quantitative perspectives in peritoneal endometriotic lesions. Utilising laser scanning confocal microscopy allowed for considerable precision in the study of endometriotic peritoneal lesion blood vessel and nerve fibre co-localisation and three-dimensional relationships.

Physical Principles of Developing Pressure Sensors Using Refractive Index Changes in Optical Fiber Microbending

The paper deals with the physical principles of development of pressure sensors using changes in the refractive index in the optical fiber microbending. The development of a simplified fiber-optic based pressure sensor is considered to be relevant for the mining industry if used as a temperature-compensated pressure sensor to avoid known disadvantages of various optical interferometers. An important point is the use of a G.652 standard single-mode optical fiber, which is also used as a guide for electrical signal transmission. The proposed information measurement system is capable of making remote measurements of the rock pressure on the powered support. The ground expressions are given to describe a physical process of the pressure measurement based on the photoelastic effect observed at microbending. The obtained results of the field experiments prove changes in the diffraction spot configuration at the optical fiber end depending on microbending. The finite element program Ansys Static Structural is used for a simulation of the mechanical stress on the optical fiber causing its microbending. The proposed sensor can detect not only pressure, but also temperature and rock mass microdisplacement and can be used for geotechnical monitoring of mine openings representing the danger of gas and coal dust explosion.

Responses of Primary Afferent Fibers to Acupuncture-Like Peripheral Stimulation at Different Frequencies: Characterization by Single-Unit Recording in Rats.

The pain-relieving effect of acupuncture is known to involve primary afferent nerves (PANs) via their roles in signal transmission to the CNS. Using single-unit recording in rats, we characterized the generation and transmission of electrical signals in Aβ and Aδ fibers induced by acupuncture-like stimuli. Acupuncture-like signals were elicited in PANs using three techniques: manual acupuncture (MAc), emulated acupuncture (EAc), and electro-acupuncture (EA)-like peripheral electrical stimulation (PES). The discharges evoked by MAc and EAc were mostly in a burst pattern with average intra-burst and inter-burst firing rates of 90 Hz and 2 Hz, respectively. The frequency of discharges in PANs was correlated with the frequency of PES. The highest discharge frequency was 246 Hz in Aβ fibers and 180 Hz in Aδ fibers. Therefore, EA in a dense-disperse mode (at alternating frequency between 2 Hz and 15 Hz or between 2 Hz and 100 Hz) best mimics MAc. Frequencies of EA output >250 Hz appear to be obsolete for pain relief.

Electrical and Mechanical Analysis of Different TSV Geometries

Through-silicon via (TSV) is an important component for implementing 3-D packages and 3-D integrated circuits as the TSV technology allows stacked silicon chips to interconnect through direct contact to help facilitate high-speed signal processing. By facilitating the stacking of silicon chips, the TSV technology also helps to meet the increasing demand for high density and high performance miniaturized electronic products. Our review of the literature shows that very few studies have reported on the impact of TSV bump geometry on the electrical and mechanical characteristics of the TSV. This paper reports on the investigation of different TSV geometries with the focus on identifying the ideal shapes for improved electrical signal transmission as well as for improved mechanical reliability. The cylindrical, quadrangular (square), elliptical, and triangular shapes were investigated in our study and our results showed that the quadrangular shape had the best electrical performance due to good characteristic impedance. Our results also showed that the quadrangular and cylindrical shapes provided improved mechanical reliability as these two shapes lead to high Cu protrusion of TSV after the annealing process.

An Efficient Alternating Segment Parallel Difference Method for the Time Fractional Telegraph Equation

The fractional telegraph equation is a kind of important evolution equation, which has an important application in signal analysis such as transmission and propagation of electrical signals. However, it is difficult to obtain the corresponding analytical solution, so it is of great practical value to study the numerical solution. In this paper, the alternating segment pure explicit-implicit (PASE-I) and implicit-explicit (PASI-E) parallel difference schemes are constructed for time fractional telegraph equation. Based on the alternating segment technology, the PASE-I and PASI-E schemes are constructed of the classic explicit scheme and implicit scheme. It can be concluded that the schemes are unconditionally stable and convergent by theoretical analysis. The convergence order of the PASE-I and PASI-E methods is second order in spatial direction and 3-α order in temporal direction. The numerical results are in agreement with the theoretical analysis, which shows that the PASE-I and PASI-E schemes are superior to the classical implicit schemes in both accuracy and efficiency. This implies that the parallel difference schemes are efficient for solving the time fractional telegraph equation.

Integrative systems and functional analyses reveal a role of dopaminergic signaling in myelin pathogenesis

BackgroundMyelin sheaths surrounding axons are critical for electrical signal transmission in the central nervous system (CNS). Diseases with myelin defects such as multiple sclerosis (MS) are devastating neurological conditions for which few effective treatments are available. Dysfunction of the dopaminergic system has been observed in multiple neurological disorders. Its role in myelin pathogenesis, however, is unclear.MethodsThis work used a combination of literature curation, bioinformatics, pharmacological and genetic manipulation, as well as confocal imaging techniques. Literature search was used to establish a complete set of genes which is associated with MS in humans. Bioinformatics analyses include pathway enrichment and crosstalk analyses with human genetic association studies as well as gene set enrichment and causal relationship analyses with transcriptome data. Pharmacological and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) genetic manipulation were applied to inhibit the dopaminergic signaling in zebrafish. Imaging techniques were used to visualize myelin formation in vivo.ResultsSystematic analysis of human genetic association studies revealed that the dopaminergic synapse signaling pathway is enriched in candidate gene sets. Transcriptome analysis confirmed that expression of multiple dopaminergic gene sets was significantly altered in patients with MS. Pathway crosstalk analysis and gene set causal relationship analysis reveal that the dopaminergic synapse signaling pathway interacts with or is associated with other critical pathways involved in MS. We also found that disruption of the dopaminergic system leads to myelin deficiency in zebrafish.ConclusionsDopaminergic signaling may be involved in myelin pathogenesis. This study may offer a novel molecular mechanism of demyelination in the nervous system.

Evaluation of Human Body Characteristics for Electric Signal Transmission Based on Measured Body Impulse Response

Human body communications (HBCs) have recently emerged as an innovative alternative to the current radio frequency communications for realizing wireless body area networks (WBANs) using the human body as a transmission channel without wired or wireless connections. This article addresses the provision of reliable modeling of the human body as a passage of the electric signal delivery based on the impulse response measurement through the proposal of a measurement setup and signal processing techniques applicable to wearable devices for healthcare and biosignal acquisition. In the experiments, customized impulse signals were applied to the body using battery-powered devices isolated to the earth ground for the operating environments of wearable devices. The impulse responses passed through the body were measured by considering 52 measurement conditions determined by the device locations from the head to ankle and the body postures. Body channel transfer functions (BCTFs) for the respective conditions were derived by an adaptive filter approach using an iterative algorithm to minimize the mean squared error between the measured and modeled impulse responses. The channel analysis parameters, such as mean path loss, root-mean-square delay spread, and mean and maximum excess delays, were analyzed based on the measured body impulse responses. In addition, the practical bit-error-rate performance for HBC based on the BCTFs reproducing intersymbol interference effects caused by the delay spreads of the body channels was explored to verify communication reliability in terms of the transmitter structures adopting digital transmission, sorts of human body channels, data rates, and operating frequencies.

Research on Physical Layer Conformance Testing Technology of Ethernet Interface

The Ethernet physical layer is located at the bottom of the network structure and is responsible for the transmission and reception of electrical signals. The performance of the physical layer will directly affect the communication quality of network devices. According to the requirements of the IEEE 802.3-2000 and ANSI X3.263-1995 standards for the physical layer of the Ethernet, the physical layer conformance test standards and requirements of the 100Base-TX and 1000Base-T network interfaces are studied, and the physical layer is designed consistently. The test method shows that the test data is accurate and the test method can meet the requirements related to the physical layer conformance test.

Connexin-mediated cell communication in the kidney: A potential therapeutic target for future intervention of diabetic kidney disease?: Joan Mott Prize Lecture.

The ability of cells to communicate and synchronise their activity is essential for the maintenance of tissue structure, integrity and function. A family of membrane-bound proteins called connexins are largely responsible for mediating the local transfer of information between cells. Assembled in the cell membrane as a hexameric connexon, they either function as a conduit for paracrine signalling, forming a transmembrane hemi-channel, or, if aligned with connexons on neighbouring cells, form a continuous aqueous pore or gap junction, which allows for the direct transmission of metabolic and electrical signals. Regulation of connexin synthesis and activity is critical to cellular function, and a number of diseases are attributed to changes in the expression and/or function of these important proteins. A link between hyperglycaemia, connexin expression, altered nucleotide concentrations and impaired function highlights a potential role for connexin-mediated cell communication in complications of diabetes. In the diabetic kidney, glycaemic injury is the leading cause of end-stage renal failure, reflecting multiple aetiologies including glomerular hyperfiltration, albuminuria, increased deposition of extracellular matrix and tubulointerstitial fibrosis. Loss of connexin-mediated cell-to-cell communication in diabetic nephropathy may represent an early sign of disease progression, but our understanding of the process remains severely limited. This review focuses on recent evidence demonstrating that glucose-evoked changes in connexin-mediated cell communication and associated purinergic signalling may contribute to the pathogenesis of kidney disease in diabetes, highlighting the tantalising potential of targeting these proteins as a novel therapeutic intervention.

Development of Welding Multi-Information Remote Wireless Monitoring System Based on STM32

A single sensor is used to obtain welding information in welding monitoring process, but this method has some shortcomings. In order to obtain more comprehensive and reliable welding information, this paper designed and built a welding multi-information wireless monitoring system with STM32-F407ZET6 as the control core and ALK8266 as the wireless transmission module. Real-time acquisition, transmission and display of electric arc signal and welding image information are realized in the monitoring system. This paper mainly introduces the hardware and software core of the monitoring system. At the same time, the signal collected by the monitoring system is compared with the original signal, and the accuracy of the remote monitoring system is tested. The monitoring system is used in welding test. The test results show that the accuracy of the monitoring system meets the requirements, and the on-line monitoring of electric arc signal and welding image can be realized in the welding process.

Could non-invasive brain-stimulation prevent neuronal degeneration upon ion channel re-distribution and ion accumulation after demyelination?

Fast and efficient transmission of electrical signals in the nervous system is mediated through myelinated nerve fibers. In neuronal diseases such as multiple sclerosis, the conduction properties of axons are disturbed by the removal of the myelin sheath, leaving nerve cells at a higher risk of degenerating. In some cases, the protective myelin sheath of axons can be rebuilt by remyelination through oligodendroglial cells. In any case, however, changes in the ion channel organization occur and may help to restore impulse conduction after demyelination. On the other hand, changes in ion channel distribution may increase the energy demand of axons, thereby increasing the probability of axonal degeneration. Many attempts have been made or discussed in recent years to increase remyelination of affected axons in demyelinating diseases such as multiple sclerosis. These approaches range from pharmacological treatments that reduce inflammatory processes or block ion channels to the modulation of neuronal activity through electrical cortical stimulation. However, these treatments either affect the entire organism (pharmacological) or exert a very local effect (electrodes). Current results show that neuronal activity is a strong regulator of oligodendroglial development. To bridge the gap between global and very local treatments, non-invasive transcranial magnetic stimulation could be considered. Transcranial magnetic stimulation is externally applied to brain areas and experiments with repetitive transcranial magnetic stimulation show that the neuronal activity can be modulated depending on the stimulation parameters in both humans and animals. In this review, we discuss the possibilities of influencing ion channel distribution and increasing neuronal activity by transcranial magnetic stimulation as well as the effect of this modulation on oligodendroglial cells and their capacity to remyelinate previously demyelinated axons. Although the physiological mechanisms underlying the effects of transcranial magnetic stimulation clearly need further investigations, repetitive transcranial magnetic stimulation may be a promising approach for non-invasive neuronal modulation aiming at enhancing remyelination and thus reducing neurodegeneration.