Thickness In Men Research Articles

An anatomical study of thenar and hypothenar soft tissue thickness in men and women.

We hypothesized that reduced thenar soft tissue thickness may be a risk factor for distal radial fractures. We assessed MRI scans of the wrist in 78 adults. The 51 men had significantly higher palmar soft tissue thickness compared to the 27 women, even after adjusting for hand size.Level of evidence: IV.

Dynamic Measurement and Analysis of Upper Eyelid Changes Using Ultrasound Biomicroscopy

PurposeTo define the regular upper eyelid anatomy and their changes during dynamic motion using ultrasonographically depicted structures. DesignA cross-sectional study. MethodsHigh-resolution ultrasound biomicroscopy (50MHz) was performed on 84 upper eyelids of 42 healthy volunteers without evidence of eyelid conditions. The skin-orbicularis oculi complex (SOOC), levator aponeurosis, and Müller's muscle-conjunctival complex were imaged. The thickness of these structures was measured in primary gaze and downgaze positions. ResultsSOOC and levator aponeurosis thickness was bigger with eyes open than with eyes closed (p < 0.01). With eyes closed, the thickness of SOOC on the pupillary midline and levator aponeurosis was positively correlated with age (p < 0.05, p < 0.01, respectively), and the thickness of levator aponeurosis and SOOC on the pupil midline was also positively correlated with BMI index (p < 0.05). Similarly, SOOC thickness on the medial and lateral canthus line is also positively correlated with BMI index and age (p < 0.05, p < 0.01, respectively). As for the differences between genders, the mean thickness of SOOC and levator aponeurosis was statistically different (p < 0.05, respectively). The magnitude of levator aponeurosis thickness in men varied more than in women in different ocular positions (p < 0.05). All measurements had an intramethod between 0.624 and 0.792, and inter-rater ICC and intrarater ICC between 0.748 and 0.850. ConclusionsUltrasound biomicroscopy represents a noninvasive tool for the visualization of upper eyelid morphology. Expanding its application can help to understand the dynamics of upper eyelid physiological movement, aging, and disease research in different populations and evaluate surgical outcomes.

Effect of abdominal tissue thickness on trabecular bone score and fracture risk in adults with diabetes: the Manitoba BMD registry.

Individuals with type 2 diabetes have lower trabecular bone score (TBS) and increased fracture risk despite higher bone mineral density. However, measures of trabecular microarchitecture from high-resolution peripheral computed tomography are not lower in type 2 diabetes. We hypothesized that confounding effects of abdominal tissue thickness may explain this discrepancy, since central obesity is a risk factor for diabetes and also artifactually lowers TBS. This hypothesis was tested in individuals aged 40years and older from a large DXA registry, stratified by sex and diabetes status. When DXA-measured abdominal tissue thickness was not included as a covariate, men without diabetes had lower TBS than women without diabetes (mean difference -0.074, P < .001). TBS was lower in women with versus without diabetes (mean difference -0.037, P < .001), and men with versus without diabetes (mean difference -0.007, P = .042). When adjusted for tissue thickness these findings reversed, TBS became greater in men versus women without diabetes (mean difference +0.053, P < .001), in women with versus without diabetes (mean difference +0.008, P < .001), and in men with versus without diabetes (mean difference +0.014, P < .001). During mean 8.7years observation, incident major osteoporotic fractures were seen in 7048 (9.6%). Adjusted for multiple covariates except tissue thickness, TBS predicted fracture in all subgroups with no significant diabetes interaction. When further adjusted for tissue thickness, HR per SD lower TBS remained significant and even increased slightly. In conclusion, TBS predicts fractures independent of other clinical risk factors in both women and men, with and without diabetes. Excess abdominal tissue thickness in men and individuals with type 2 diabetes may artifactually lower TBS using the current algorithm, which reverses after accounting for tissue thickness. This supports ongoing efforts to update the TBS algorithm to directly account for the effects of abdominal tissue thickness for improved fracture risk prediction.

Do age at diagnosis, tumour thickness and tumour site explain sex differences in melanoma survival? A causal mediation analysis using cancer registry data.

Women diagnosed with melanoma have better survival than men, but little is known about potential intervention targets to reduce this survival gap by sex. We conducted a population-based study using Victorian Cancer Registry data including 5833 women and 6780 men aged 15 to 70 years when diagnosed with first primary melanoma between 2007 and 2015. Deaths to the end of 2020 were identified through linkage to the Victorian and national death registries. We estimated the effect of age at diagnosis, tumour thickness and tumour site on reducing the melanoma-specific survival gap by sex (ie, interventional indirect effects [IIEs]) on risk difference (RD) scale. Compared to women, there were 211 (95% CI: 145-278) additional deaths per 10 000 in men within 5 years following diagnosis. We estimated that 44% of this gap would be reduced by a hypothetical intervention shifting the distribution of melanoma thickness in men to be the same as that observed for women (IIEthickness RD 93 [95% CI: 75-118] per 10 000) and 20% by an intervention on tumour site (head and neck/trunk vs upper limb/lower limb; IIEsite RD 42 [95% CI: 15-72] per 10 000), while an intervention on age at diagnosis would have a negligible effect. Tumour thickness, tumour site and age at diagnosis mediated 65% of the effect of sex on 5-year melanoma survival in Victoria. Of these factors, tumour thickness had the most considerable mediating effect, suggesting that effective promotion of earlier detection of melanoma in men could potentially nearly halve the gap in melanoma-specific survival by sex.

Links between psychopathological symptoms and cortical thickness in men with severe alcohol use disorder: A Magnetic Resonance Imaging study.

Anxiety and depression are psychopathological states frequently co-occurring with severe alcohol use disorder (SAUD). These symptoms generally disappear with abstinence but may persist in some patients, increasing the relapse risk. The cerebral cortex thickness of 94 male patients with SAUD was correlated with symptoms of depression and anxiety, both measured at the end (2-3 weeks) of the detoxification treatment. Cortical measures were obtained using surface-based morphometry implemented with Freesurfer. Depressive symptoms were associated with reduced cortical thickness in the superior temporal gyrus of the right hemisphere. Anxiety level was correlated with lower cortical thickness in the rostral middle frontal region, inferior temporal region, and supramarginal, postcentral, superior temporal, and transverse temporal regions of the left hemisphere, as well as with a large cluster in the middle temporal region of the right hemisphere. At the end of the detoxification stage, the intensity of depressive and anxiety symptoms is inversely associated with the cortical thickness of regions involved in emotions-related processes, and the persistence of the symptoms could be explained by these brain deficits.

Associations of Particulate Matter Exposures With Brain Gray Matter Thickness and White Matter Hyperintensities: Effect Modification by Low-Grade Chronic Inflammation.

Numerous studies have shown the effect of particulate matter exposure on brain imaging markers. However, little evidence exists about whether the effect differs by the level of low-grade chronic systemic inflammation. We investigated whether the level of c-reactive protein (CRP, a marker of systemic inflammation) modifies the associations of particulate matter exposures with brain cortical gray matter thickness and white matter hyperintensities (WMH). We conducted a cross-sectional study of baseline data from a prospective cohort study including adults with no dementia or stroke. Long-term concentrations of particulate matter ≤ 10 µm in diameter (PM10) and ≤ 2.5 µm (PM2.5) at each participant's home address were estimated. Global cortical thickness (n = 874) and WMH volumes (n = 397) were estimated from brain magnetic resonance images. We built linear and logistic regression models for cortical thickness and WMH volumes (higher versus lower than median), respectively. Significance of difference in the association between the CRP group (higher versus lower than median) was expressed as P for interaction. Particulate matter exposures were significantly associated with a reduced global cortical thickness only in the higher CRP group among men (P for interaction = 0.015 for PM10 and 0.006 for PM2.5). A 10 μg/m3 increase in PM10 was associated with the higher volumes of total WMH (odds ratio, 1.78; 95% confidence interval, 1.07-2.97) and periventricular WMH (2.00; 1.20-3.33). A 1 μg/m3 increase in PM2.5 was associated with the higher volume of periventricular WMH (odds ratio, 1.66; 95% confidence interval, 1.08-2.56). These associations did not significantly differ by the level of high sensitivity CRP. Particulate matter exposures were associated with a reduced global cortical thickness in men with a high level of chronic inflammation. Men with a high level of chronic inflammation may be susceptible to cortical atrophy attributable to particulate matter exposures.

The Beneficial Changes on Inflammatory and Endothelial Biomarkers Induced by Metabolic Surgery Decreases the Carotid Intima-Media Thickness in Men.

Obesity increases cardiovascular risk in men through several mechanisms. Among them, low-grade chronic inflammation and obesity-associated hypogonadism have been described. We aimed to study the effects of metabolic surgery on the carotid-intima media thickness through changes in inflammatory, endothelial biomarkers, and testosterone. We included 60 men; 20 submitted to laparoscopic Roux-en-Y gastric bypass (RYGB), 20 to sleeve gastrectomy (SG), and 20 to lifestyle modification (controls). Several inflammatory and endothelial biomarkers and total testosterone (TT) were measured at baseline and six months after surgery. Free testosterone (FT) was calculated, and carotid intima-media thickness (cIMT) was measured by ultrasonography. Compared to controls, cIMT decreased after surgery concomitantly with CRP, PAI-1, sICAM-1, and IL-18 (p < 0.01) and with an increase in sTWEAK (p = 0.027), with no differences between RYGB and SG. The increase in TT and FT after surgery correlated with the changes in cIMT (p = 0.010 and p = 0.038, respectively), but this association disappeared after multivariate analysis. Linear regression showed that sTWEAK (ß = -0.245, p = 0.039), PAI-1 (ß = 0.346, p = 0.005), and CRP (ß = 0.236, p = 0.049) were associated with the changes in cIMT (R2 = 0.267, F = 6.664, p = 0.001). In conclusion, both RYGB and SG induced improvements in inflammation and endothelial biomarkers that drove a decrease in cIMT compared to men with obesity who submitted to diet and exercise.

Cremaster muscle thickening: the anatomic difference in men with testicular retraction due to hyperactive cremaster muscle reflex.

The objective was to assess whether men suffering from testicular retraction secondary to hyperactive cremaster muscle reflex have an anatomic difference in the thickness of the cremaster muscle in comparison to men who do not have retraction. From March 2021 to December 2021, 21 men underwent microsurgical subinguinal cremaster muscle release (MSCMR) on 33 spermatic cord units, as 12 of them had bilateral surgery, at Surgicare of South Austin Ambulatory Surgery Center in Austin, TX, USA. During that same time frame, 36 men underwent subinguinal microsurgical varicocele repair on 41 spermatic cord units, as 5 were bilateral for infertility. The thickness of cremaster muscles was measured by the operating surgeon in men undergoing MSCMR and varicocele repair. Comparison was made between the cremaster muscle thickness in men with testicular retraction due to a hyperactive cremaster muscle reflex undergoing MSCMR and the cremaster muscle thickness in men undergoing varicocele repair for infertility with no history of testicular retraction, which served as an anatomic control. The mean cremaster muscle thickness in men who underwent MSCMR was significantly greater than those undergoing varicocele repair for infertility, with a mean cremaster muscle thickness of 3.9 (standard deviation [s.d.]: 1.2) mm vs 1.0 (s.d.: 0.4) mm, respectively. Men with testicular retraction secondary to a hyperactive cremaster muscle reflex demonstrate thicker cremaster muscles than controls, those undergoing varicocele repair. An anatomic difference may be a beginning to understanding the pathology in men who struggle with testicular retraction.

Associations of particulate matter exposures with brain cortical thickness and white matter hyperintensities: effect modification by c-reactive protein

Background and aim: Numerous studies have shown the effect of particulate matter exposure on brain imaging markers. However, little evidence exists about whether the effect differs by the level of systemic inflammation, a mechanism of neurotoxicity of particulate matter. We investigated whether the level of c-reactive protein (CRP; a marker of systemic inflammation) modifies the associations of particulate matter exposures with brain cortical thickness and white matter hyperintensities (WMH). Methods: Adults with no dementia or stroke were recruited. Concentrations of particulate matter &amp;#x2264;10 µm in diameter (PM10) and &amp;#x2264;2.5 µm (PM2.5) at each participant’s home address were estimated. Mean cortical thickness (n=874) and WMH volumes (n=397) were estimated from brain magnetic resonance images. We built generalized linear and logistic regression models for mean cortical thickness and WMH volumes (higher versus lower than median), respectively. Significance of the CRP group (higher versus lower than median) difference in the association was expressed as p for interaction. Results: Particulate matter exposures were significantly associated with a reduced mean cortical thickness only in the higher CRP group among men (p for interaction=0.012 for PM10 and 0.006 for PM2.5). A 10 &amp;#x3bc;g/m3 increase in PM10 was associated with having higher volumes of total WMH (odds ratio, 1.67; 95% confidence interval, 1.01–2.76) and periventricular WMH (1.81; 1.10–2.98). A 1 &amp;#x3bc;g/m3 increase in PM2.5 was associated with having a higher volume of periventricular WMH (odds ratio, 1.53; 95% confidence interval, 1.01–2.33). These associations did not significantly differ by the level of CRP. Conclusions: Particulate matter exposures were associated with a reduced mean cortical thickness in men with a high level of systemic inflammation. Particulate matter exposures were associated with having a high volume of WMH, with no evidence of effect modification by the level of systemic inflammation. Keywords: air pollution; neuroimaging; inflammation

Skinfold thickness in men and women with seborrheic dermatitis of varying severity

Significant progress has been made in the diagnosis of seborrheic dermatitis. It is based on the anamnesis and clinical picture of skin lesions. Carrying out a detailed analysis of the structure and size of the body in combination with clinical and instrumental studies allows us to further make a more reliable prognosis of complications of this disease and improve the results of treatment of such patients. The aim of the study was to establish and analyze the features of the skinfold thickness in Ukrainian men and women with seborrheic dermatitis of varying severity. Skinfold thickness (SFT) was determined in 40 men and 40 women (aged 25 to 44 years) with generalized fatty seborrheic dermatitis (mild and severe). The control group consisted of SFT values of practically healthy men (n=82) and women (n=154) of the same age group from the database of the research center National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of SFT indicators was performed in the license package “Statistica 6.0” using non-parametric evaluation methods. Compared with practically healthy men, patients with mild and severe seborrheic dermatitis had lower SFT values on the posterior (by 49.7 % and 46.5 %) and anterior (by 41.9 % and 46.4 %) surfaces of the shoulder and chest (by 28.9 % and 27.9 %), on the thigh (47.3 % and 38.3 %), on the forearm (only compared to severe severity by 18.5 %), at the lower angle of the shoulder blade (only compared to mild severity by 3.5 %) and on the shin (only compared to severe severity by 15.9 %), as well as higher values of SFT on the side (by 36.7 % and 51.6 %); and in women patients of varying severity– also lower values of SFT on the posterior surface of the shoulder (by 51.0 % and 43.6 %), on the anterior surface of the shoulder (by 46.6 % and 31.0 %), on the chest (by 31.3 % and 18.9 %), on thighs (by 47.4 % and 38.9 %) and on the shin (only compared to the mild degree by 10.2 %), as well as higher values of SFT on the side (by 37.0 % and 44.6 %). Among men or women with seborrheic dermatitis of varying severity, only higher values were found in women with severe SFT on the anterior surface of the shoulder (by 22.6 %), and in men with severe severity – higher values of SFT on the thigh (by 14.6 %). Manifestations of sexual dimorphism of SFT among patients with seborrheic dermatitis of varying severity were found only between men and women with severe disease, namely, higher values of SFT in women on the front shoulder surface (by 28.6 %), forearm (by 16.0 %) and on the shin (by 26.3 %).

Rapid eye movement sleep apnea and carotid intima thickness in men and women: a SHE-MUSTACHE cohort study.

Rapid eye movement (REM) obstructive sleep apnea might be particularly harmful to the cardiovascular system. We aimed to investigate the association between sleep apnea during REM sleep and signs of atherosclerotic disease in the form of carotid intima thickness in a community-based sample of men and women and possible sex differences in this association. The association between sleep apnea during REM sleep and intima thickness was analysed cross-sectionally in women from the community-based "Sleep and Health in Women" (SHE) study (n=253) and age- and body mass index (BMI)-matched men from the "Men in Uppsala; a Study of sleep, Apnea and Cardiometabolic Health" (MUSTACHE) study (n=338). Confounders adjusted for were age, BMI, gender, alcohol, and smoking. All participants underwent a full-night polysomnography, high-resolution ultrasonography of the common carotid artery, anthropometric measurements, blood pressure measurements, and answered questionnaires. There was an association between sleep apnea during REM sleep and thicker carotid intima that remained after adjustment for confounding (adjusted β=0.008, p=0.032). The intima was increased by 9.9% in the group with severe sleep apnea during REM sleep, and this association between severe sleep apnea during REM sleep and increased intima thickness remained after adjustment for confounders (adjusted β=0.043, p=0.021). More women than men had severe sleep apnea during REM sleep; moreover, in sex-stratified analyses, the association between sleep apnea during REM sleep and intima thickness was found in women but not in men. We conclude that severe REM sleep apnea is independently associated with signs of atherosclerosis. When stratified by sex, the association is seen in women but not in men.

Features of skinfold thickness in men with benign nevi

Nevi, although benign neoplasms of the skin, but have a certain tendency to malignancy, which is influenced by various external and internal human factors. Predicting the risk of benign nevi against this background is an important topic for experimental research. The aim of the study was to establish the features of the skinfold thickness (SFT) in men of the first adult age with benign nevi. SFT was determined according to the Bunak scheme for men (aged 22-35 years) with melanocyte benign simple nevi (n=34), melanocyte benign dysplastic nevi (n=27), melanocyte benign congenital nevi (n=14) and non-melanocyte benign (n=17). The control group – SFT of 82 practically healthy men of the same age group was selected from the data bank of the Research Center of National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of the results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. It was found that in practically healthy men higher than in patients – SFT on the anterior and posterior surfaces of the shoulder and thigh (in all groups of patients); SFT on the forearm, at the lower angle of the scapula, chest and shin (only in patients with melanocyte benign dysplastic nevi). Also in healthy men are found lower than in patients – SFT on the side (in all groups of patients); SFT in the abdomen (in patients with melanocyte benign simple and non-melanocyte benign nevi). When comparing SFT between patients with benign nevi, in most cases, lower values of SFT found in patients with melanocyte benign dysplastic nevi. The obtained results indicate the initial manifestations of abdominal (android) type of fat deposition in the body in patients with benign nevi (most pronounced in patients with melanocyte benign simple nevi).

Skinfold thickness in men with mild and severe psoriasis without and taking into account the somatotype

Significant prevalence and decline in quality of life caused by psoriasis in combination with the lack of etiotropic methods of its treatment, put this disease, in terms of relevance for modern medicine on a par with diabetes, hypertension, asthma etc. That is, there is a need to find easily accessible markers that would determine the susceptibility to this disease. The aim of the study was to establish the differences in the skinfold thickness between healthy and/or psoriatic Ukrainian men depending on the severity of the disease without and taking into account the somatotype. For 32 Ukrainian men of the first mature age, patients with mild psoriasis and 68 men with severe psoriasis (according to the PASI index) were determined skinfold thickness according to Bunak and determined the somatotype according to the Heath-Carter scheme. The control group consisted of 82 healthy men of similar age, selected from the database of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. It was found that in patients with mild or severe psoriasis of men without division into somatotypes and in representatives of the mesomorphic somatotype compared to healthy men, the skinfold thickness is significantly higher at the lower angle of the scapula, abdomen and side, and significantly lower on the back and front of the shoulder, chest and thighs. When comparing the skinfold thickness between patients with mild or severe psoriasis of endo-mesomorphic somatotype with healthy men of similar somatotype, we found larger values of the skinfold thickness under the lower angle of the scapula (only with mild course), on the abdomen and side, and also smaller values of the skinfold thickness on the posterior surface of the shoulder and only in representatives with severe psoriasis – on the anterior surface of the shoulder, chest and thigh. Between patients with different degrees of severity of dermatosis both without distribution, and with distribution on various somatotypes of reliable or tendencies of differences of skinfold thickness are not revealed. Thus, there are pronounced differences in most indicators of the skinfold thickness between healthy and patients with mild or severe psoriasis of Ukrainian men of the first mature age, both without distribution and with the division into different somatotypes.

Platelet-rich plasma as a therapy for androgenic alopecia: a systematic review and meta-analysis

Objective The past decade has seen platelet-rich plasma (PRP) become a popular therapy around the world as a treatment for androgenetic alopecia (AGA). These systematic review and meta-analyses assess the effectiveness and adverse effects of PRP to determine the role of PRP as a treatment for AGA among the other non-surgical treatment modalities. Methods This study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and is registered under the PROSPERO ID CRD42019136329. Seven databases were searched from inception through May 2019. Meta-analyses of randomized controlled trials (RCTs) were performed to evaluate the effect of PRP treatments on hair density and hair thickness. Results Thirty studies, including 687 patients, met our inclusion criteria. Twenty-nine studies reported beneficial results, and 24 studies reached statistical significance on a measured outcome. Ten RCTs were included. Our meta-analyses show that PRP treatment increases hair density and hair thickness. Conclusions PRP is an autologous treatment that lacks serious adverse effects and effectively improves hair density and hair thickness in men and women with AGA. Future research should include low risk-of-bias RCTs to optimize treatment protocols, investigate variability among studies, and to obtain more data on hair thickness changes.

Rectus Abdominis Muscle Thickness is a Valid Measure of Cross-Sectional Area: Implications for Ultrasound

The rectus abdominis muscle exhibits early and significant muscle atrophy, which has largely been characterized using ultrasound measured muscle thickness. However, the validity of rectus abdominis muscle thickness as a metric of muscle size has not been established, limiting precise interpretation of age-related changes. In a heterogeneous cohort of women and men, our objectives were to: (1) evaluate the association between rectus abdominis muscle thickness and cross-sectional area (CSA), and (2) examine if the visceral adipose tissue (VAT) compartment confounds the validity of rectus abdominis muscle thickness. Abdominal computed tomography scans of the third lumbar vertebrae from clinical and healthy populations were used to evaluate rectus abdominis thickness and CSA, and VAT CSA. Computed tomography scans were utilized due to the limited field of view of ultrasound imaging to capture the rectus abdominis CSA. A total of 348 individuals (31% women) were included in this analysis, with a mean ± standard deviation age and body mass index of 51.2 ± 15.4 years and 28.0 ± 5.1 kg/m2, respectively. Significant correlations were observed between rectus abdominis thickness and CSA for women (r=0.758; p < 0.001) and men (r=0.688; p < 0.001). Independent of age, VAT CSA was negatively associated with rectus abdominis thickness in men (p = 0.011), but not women (p = 0.446). These data support the use of rectus abdominis muscle thickness as a measurement of muscle size in both women and men; however, the VAT compartment may confound its validity to a minor extent in men.

Maxillary width and hard palate thickness in men and women with different vertical and sagittal skeletal patterns

The objective of this research was to compare maxillary width and hard palate thickness in men and women with different vertical and sagittal skeletal patterns. A total of 241 adults (93 men and 148 women aged from 18 to 25years) were divided into male and female groups. Subjects were then separately divided into 3 sagittal skeletal groups and 3 vertical skeletal groups. A lateral cephalogram and a cone-beam computed tomography were taken for each subject. We measured the parameters to make statistical analyses and compared them between the different groups. Women had smaller craniomaxillofacial bone width and palatal thickness than men. In sagittal groups, maxillary width, maxillary alveolar width, and external temporomandibular joint fossa width in Class II and Class III malocclusion groups were smaller than in the Class I group for both women and men. The internal temporomandibular joint fossa width was the same results in men and women. In vertical groups, palate thickness, maxillary width, and maxillary alveolar width of the high-angle group were smaller than those of the low-angle group, regardless of sex. To an extent, maxillary width is correlated with vertical and sagittal skeletal patterns, and insufficient maxillary width would lead to unfavorable skeletal patterns. Differences exist in the morphology of craniomaxillofacial bone between men and women. Therefore, these findings can provide clinicians with references for differential diagnosis and treatment plans.

Anthropometric Measurements Of The Ventrogluteal İnjectıon Area: A Cross-sectional Study

Research Problem / Aim: The ventrogluteal injection area is one of the areas most frequently used by nurses in intramuscular injection applications. The thicknesses of the subcutaneous tissue and the muscle tissue in this area are important for a safe injection. The aim of this study is the determination of the subcutaneous and muscle tissue thicknesses on the ventrogluteal injection area and the anthropometric data about it.&#x0D; Method: The study has designed a cross-sectional study. 150 individuals who applied to the ultrasound unit of the hospital and accepted to participate in the study were included in the study. The ventrogluteal injection area was determined with the ‘’V’’ method by the researcher. The subcutaneous and muscle tissue thicknesses from the areas on the injection area and the areas 2 and 4 cm around the injection area were determined using the ultrasound device. Moreover, the relation between the anthropometric measurements of the individuals (height, weight, waist, hip and crista iliaca circumferences, distance between the large trochanter and crista iliaca and crista iliaca anterior) and the tissue thicknesses on the injection area were evaluated. The data of the research were evaluated with definitive statistics, ANOVA test and posthoc Tukey test, t test and correlation analysis. The p&lt;0.05 value was accepted as statistically significant for all results.&#x0D; Findings: The average subcutaneous tissue thickness in the injection area was determined as 15.44±8.01 mm and the average tissue thickness there was determined as 31.75±11.86 mm. The subcutaneous tissue thickness in women was found more than the subcutaneous tissue thickness in men. When the tissue thicknesses 2 and 4 cm around the injection area were analyzed, it was found that the area where the total tissue thickness was the least was over 2 cm (41.67±14.83) and over 4 cm (35.79±15.55) of the injection area. It was determined that the average total thickness 4 cm around the injection area was less than 38 mm in underwight individuals.&#x0D; Conclusions: According to the results obtained from the study, the weight and body mass index of the individual should be considered in the choice of the injection area and the length of the needle to be used when the ventrogluteal injection area was used in intramuscular injections. Especially in obese individuals, longer needles can be preferred. Besides, it must be thought that there may be the risk of bone injury 4 cm around the injection area in asthenic individuals and individuals with normal weight. Moreover, since the individuals’ having a large waist and hip circumference is related to their subcutaneous tissue thickness, it is recommended that long needles should be chosen in these individuals.

Age- and sex-related characteristics in cortical thickness of femoral diaphysis for young and elderly subjects.

Cortical thickness of the femoral diaphysis is assumed to be a preferred parameter in the assessment of the structural adaptation by mechanical use and biological factors. This study aimed to investigate the age- and sex-specific characteristics in cortical thickness of the femoral diaphysis between young and elderly non-obese people. This study investigated 34 young subjects (21 men and 13 women; mean age: 27 ± 8years) and 52 elderly subjects (29 men and 23 women; mean age: 70 ± 6 years). Three-dimensional (3D) cortical thickness of the femoral diaphysis was automatically calculated for 5000-8000 measurement points using the high-resolution cortical thickness measurement from clinical CT data. In 12 assessment regions created by combining three heights (proximal, central, and distal diaphysis) and four areas of the axial plane at 90° (medial, anterior, lateral, and posterior areas) in the femoral coordinate system, the standardized thickness was assessed using the femoral length. As per the trends, (1) there were no differences in medial and lateral thicknesses, while the posterior thickness was greater than the anterior thickness, (2) the thickness in men was higher than that in women, and (3) the thickness in young subjects was higher than that in elderly subjects. The results of this study are of clinical relevance as reference points to clarify the causes of various pathological conditions for diseases of the lower extremities.

Correlation Between Prostate Volume Measured by Ultrasound and Detrusor Wall Thickness in Men with Benign Prostatic Hypertrophy.

Background:Benign prostatic hypertrophy (BPH) causes subvesical urinary obstruction in the elderly. It leads to changes in the bladder and upper urinary tract. This may be progressive with subsequent morbidities and mortalities. This study aims at determining the relationship between ultrasound-measured prostate volume and detrusor wall thickness (DWT) in men with BPH.Materials and Methods:One hundred and ten patients who met the inclusion criteria and were diagnosed with clinical BPH were enrolled. They had no other identifiable cause of bladder outlet obstruction. The International Prostate Symptoms Score (IPSS), Quality of Life (QOL) score, prostate volume, and DWT were measured. Correlation between prostate volume and DWT was done using SPSS version 20.0 (IBM, SPSS, Chicago, IL, USA). A P-value less than 0.05 was considered significant.Results:The mean age of patients was 68.3 ± 10.2 years, with a range of 40–100 years. The mean prostate volume and DWT were 94.2 ± 68.4 cm3 and 5.9 ± 3.0 mm, respectively. Mean QOL was 4.77 ± 1.35. The highest IPSS was 35 and lowest was 2. Nocturia was the major IPSS subscore. There was a positive correlation between prostate volume and DWT in men with BPH (r = 0.37; P = 0.007). This is statistically significant.Conclusion:Ultrasound-measured prostate volume correlates positively with DWT in men with BPH. This is statistically significant and is able to determine progression of the disease. Coexisting large prostate volume and thickened detrusor wall are an indicator of disease progression and eventual need for surgical intervention. This prevents renal damage.

Cutaneous nevi and risk of melanoma death in women and men: A prospective study

It was unclear whether an increased number of common nevi (moles) predicts melanoma death. We prospectively examined the association between number of common nevi and risk of melanoma death. Our study used data from the Nurses' Health Study (n=77,288 women) and Health Professionals Follow-up Study (n=32,455 men). In 1986, participants were asked about the number of moles they had with a ≥3-mm diameter on the upper extremity, and we stratified their answers into 3 categories (none, 1-2, or ≥3) on the basis of data distribution. During follow-up (1986-2012), 2452 melanoma cases were pathologically confirmed; among these, we identified 196 deaths due to melanoma. Increased number of nevi was associated with melanoma death; the hazard ratio (HR) for ≥3 nevi compared with no nevi was 2.49 (95% confidence interval [CI] 1.50-4.12) for women and 3.97 (95% CI 2.54-6.22) for men. Among melanoma cases, increased number of nevi was associated with melanoma death in men (≥3 nevi, HR 1.89, 95% CI 1.17-3.05) but not in women. Similarly, the number of nevi was positively associated with Breslow thickness in men only (Ptrend=.01). This is an epidemiologic study without examination into mechanisms. Increased number of cutaneous nevi was significantly associated with melanoma death. High nevus count might serve as an independent prognostic factor to predict the risk of melanoma death particularly among male melanoma patients.