Abstract

Significant prevalence and decline in quality of life caused by psoriasis in combination with the lack of etiotropic methods of its treatment, put this disease, in terms of relevance for modern medicine on a par with diabetes, hypertension, asthma etc. That is, there is a need to find easily accessible markers that would determine the susceptibility to this disease. The aim of the study was to establish the differences in the skinfold thickness between healthy and/or psoriatic Ukrainian men depending on the severity of the disease without and taking into account the somatotype. For 32 Ukrainian men of the first mature age, patients with mild psoriasis and 68 men with severe psoriasis (according to the PASI index) were determined skinfold thickness according to Bunak and determined the somatotype according to the Heath-Carter scheme. The control group consisted of 82 healthy men of similar age, selected from the database of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. It was found that in patients with mild or severe psoriasis of men without division into somatotypes and in representatives of the mesomorphic somatotype compared to healthy men, the skinfold thickness is significantly higher at the lower angle of the scapula, abdomen and side, and significantly lower on the back and front of the shoulder, chest and thighs. When comparing the skinfold thickness between patients with mild or severe psoriasis of endo-mesomorphic somatotype with healthy men of similar somatotype, we found larger values of the skinfold thickness under the lower angle of the scapula (only with mild course), on the abdomen and side, and also smaller values of the skinfold thickness on the posterior surface of the shoulder and only in representatives with severe psoriasis – on the anterior surface of the shoulder, chest and thigh. Between patients with different degrees of severity of dermatosis both without distribution, and with distribution on various somatotypes of reliable or tendencies of differences of skinfold thickness are not revealed. Thus, there are pronounced differences in most indicators of the skinfold thickness between healthy and patients with mild or severe psoriasis of Ukrainian men of the first mature age, both without distribution and with the division into different somatotypes.

Highlights

  • Psoriasis is a chronic immune-mediated inflammatory skin disease that has a chronic recurrent course that significantly affects the quality of life of patients

  • Between healthy and mild psoriasis men of endo-mesomorphic somatotype, the picture of differences in the skinfold thickness is slightly different: in contrast to the established differences without division into somatotypes, there are no significant differences in the skinfold thickness on the front surface of the shoulder, chest and thighs

  • Between healthy and severe psoriasis men of mesomorphic somatotype, the pattern of differences in the skinfold thickness is almost similar to the established differences in men without division into somatotypes and between healthy and mild course of psoriasis mesomorphic men

Read more

Summary

Introduction

Psoriasis is a chronic immune-mediated inflammatory skin disease that has a chronic recurrent course that significantly affects the quality of life of patients. The prevalence of the disease is heterogeneous, but there is a peculiar trend when it is more prevalent in highincome countries. In the United Kingdom the prevalence is 2.2 %, in Norway 4.5 %, in the United States 2.2 %-3.15 %, and in Africa, Asia and Latin America the average is 0.5 % [18, 20]. In the United States as of 2010, 7.2 million people suffered from psoriasis, and in 2013 this figure was already 7.4 million people. In general the authors of the study claim that since the early 2000s the number of patients with psoriasis in the country has stabilized [21]

Objectives
Methods
Results
Discussion
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call