This paper utilizes the CNKI journal database to retrieve literature related to "school-enterprise collaboration" and "innovation and entrepreneurship". It employs bibliometrics and utilizes CiteSpace for quantitative analysis and information mining, demonstrating the spatial distribution characteristics and evolutionary context of research on school-enterprise collaboration in innovation and entrepreneurship. The research results indicate that the academic community has a high level of interest in the topic of school-enterprise collaboration in innovation and entrepreneurship, covering aspects such as the current situation of talent cultivation, problem analysis, platform research for nurturing talents, and student innovation and entrepreneurship ability cultivation, and has achieved certain results. However, research on the talent cultivation system of school-enterprise collaboration in innovation and entrepreneurship is still in its early stages, and a systematic theoretical model has not yet been formed. Therefore, establishing a systematic ecological model for talent cultivation in school-enterprise collaboration in innovation and entrepreneurship, and strengthening research on ensuring the operation of the talent cultivation system for school-enterprise collaboration in innovation and entrepreneurship, will become an important trend in future research on talent cultivation in school-enterprise collaboration in innovation and entrepreneurship.